Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/7f/02be609fef63290329643b004c59d4/aih-tih-sc-951f98-R1_A23WJ53LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5b/7791d38f33f29eca2f7ca4a9f94089/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5b/7791d38f33f29eca2f7ca4a9f94089/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5ae5f7b1-ce8a-4a12-9374-820c751df9c5/09/a7ecdb27117590dd6e7bf9e221420e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 232
  Pass (FILTER=PASS): 21 (9.1%)
  Fail (FILTER=FAIL): 211 (90.9%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 5
  All 5 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 61
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 26
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 19
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 17
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 17
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 16
  confidence_below_min(low<high): 13
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 8
  total_reads_below_min(4.0<8.0): 3
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0);aih_curated_blacklist: 1

Breakdown by confidence:
  high: 21 pass, 3 fail (total: 24)
  low: 0 pass, 87 fail (total: 87)
  medium: 0 pass, 121 fail (total: 121)
Arriba filter: 232 rows -> 21 PASS; wrote aih-tih-sc-951f98-R1_A23WJ53LT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-951f98-R1_A23WJ53LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-951f98-R1_A23WJ53LT4_1.arriba.fusions.filter_summary.txt