Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/bb/16d007a84c8958ef4628f6e4537d44/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/bb/16d007a84c8958ef4628f6e4537d44/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a3/cef8170c9720a6ab13905c73972128/aih-tih-sc-431fe7-R1_A23WJ53LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5ae5f7b1-ce8a-4a12-9374-820c751df9c5/09/a7ecdb27117590dd6e7bf9e221420e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 3 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 56
Pass (FILTER=PASS): 4 (7.1%)
Fail (FILTER=FAIL): 52 (92.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 3
All 3 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 5
confidence_below_min(low<high): 5
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(medium<high): 2
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
total_reads_below_min(5.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0);aih_curated_blacklist: 1
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 1
Breakdown by confidence:
high: 4 pass, 1 fail (total: 5)
low: 0 pass, 31 fail (total: 31)
medium: 0 pass, 20 fail (total: 20)
Arriba filter: 56 rows -> 4 PASS; wrote aih-tih-sc-431fe7-R1_A23WJ53LT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-431fe7-R1_A23WJ53LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-431fe7-R1_A23WJ53LT4_1.arriba.fusions.filter_summary.txt