Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/77/2654c5ba678e8b2db54f734b5aa351/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/77/2654c5ba678e8b2db54f734b5aa351/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a7/2e2f4093012c5c2d919effcc87984d/aih-tih-sc-3eb8dd-R1_A23WJ53LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5ae5f7b1-ce8a-4a12-9374-820c751df9c5/09/a7ecdb27117590dd6e7bf9e221420e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 173
Pass (FILTER=PASS): 20 (11.6%)
Fail (FILTER=FAIL): 153 (88.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 30
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 28
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 16
confidence_below_min(low<high): 13
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0);aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
Breakdown by confidence:
high: 20 pass, 1 fail (total: 21)
low: 0 pass, 95 fail (total: 95)
medium: 0 pass, 57 fail (total: 57)
Arriba filter: 173 rows -> 20 PASS; wrote aih-tih-sc-3eb8dd-R1_A23WJ53LT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-3eb8dd-R1_A23WJ53LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-3eb8dd-R1_A23WJ53LT4_1.arriba.fusions.filter_summary.txt