Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b1/bf3880828c634d5a595acf9c052617/aih-tih-sc-3e4d53-R1_A23WJ53LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/af/3ac299119a3b0e6013458570f681fb/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/af/3ac299119a3b0e6013458570f681fb/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5ae5f7b1-ce8a-4a12-9374-820c751df9c5/09/a7ecdb27117590dd6e7bf9e221420e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 10 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 381
  Pass (FILTER=PASS): 45 (11.8%)
  Fail (FILTER=FAIL): 336 (88.2%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 10
  All 10 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 89
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 53
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 37
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 19
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 18
  confidence_below_min(low<high): 18
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 13
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 13
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 12
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 7
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 6
  total_reads_below_min(3.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4

Breakdown by confidence:
  high: 45 pass, 15 fail (total: 60)
  low: 0 pass, 151 fail (total: 151)
  medium: 0 pass, 170 fail (total: 170)
Arriba filter: 381 rows -> 45 PASS; wrote aih-tih-sc-3e4d53-R1_A23WJ53LT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-3e4d53-R1_A23WJ53LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-3e4d53-R1_A23WJ53LT4_1.arriba.fusions.filter_summary.txt