Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/8d/0d8cca938838c15a39f8f9fe22e379/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/8d/0d8cca938838c15a39f8f9fe22e379/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ca/b2a4a5ed27a5d58e6fedabbbd8cd12/aih-tih-sc-0992e4-R1_A23WJ53LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5ae5f7b1-ce8a-4a12-9374-820c751df9c5/09/a7ecdb27117590dd6e7bf9e221420e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 244
Pass (FILTER=PASS): 21 (8.6%)
Fail (FILTER=FAIL): 223 (91.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 12
All 12 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 80
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 25
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 23
confidence_below_min(low<high): 16
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(medium<high);aih_curated_blacklist: 5
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
total_reads_below_min(3.0<8.0): 2
Breakdown by confidence:
high: 21 pass, 6 fail (total: 27)
low: 0 pass, 106 fail (total: 106)
medium: 0 pass, 111 fail (total: 111)
Arriba filter: 244 rows -> 21 PASS; wrote aih-tih-sc-0992e4-R1_A23WJ53LT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-0992e4-R1_A23WJ53LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-0992e4-R1_A23WJ53LT4_1.arriba.fusions.filter_summary.txt