Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c7/c9a09de23cd35adc233143b4b1fc13/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c7/c9a09de23cd35adc233143b4b1fc13/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a3/6985ea74a97d7de1d8569e83d419ea/tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 70
Pass (FILTER=PASS): 6 (8.6%)
Fail (FILTER=FAIL): 64 (91.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 5
All 5 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 7
confidence_below_min(low<high): 5
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
confidence_below_min(medium<high): 3
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);aih_curated_blacklist: 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 6 pass, 0 fail (total: 6)
low: 0 pass, 49 fail (total: 49)
medium: 0 pass, 15 fail (total: 15)
Arriba filter: 70 rows -> 6 PASS; wrote tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.filtered.tsv and tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.filter_summary.txt