Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b7/c7c6b377edab42c26fed21ebdfb30e/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d5/ac19013baf6be7418d3adc0319ea47/tih_rna_sample_00149_B23WHTKLT4_2.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b7/c7c6b377edab42c26fed21ebdfb30e/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 229
  Pass (FILTER=PASS): 27 (11.8%)
  Fail (FILTER=FAIL): 202 (88.2%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 6
  All 6 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 44
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 24
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 21
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 17
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 16
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 9
  confidence_below_min(low<high): 6
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 5
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
  total_reads_below_min(6.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3

Breakdown by confidence:
  high: 27 pass, 9 fail (total: 36)
  low: 0 pass, 75 fail (total: 75)
  medium: 0 pass, 118 fail (total: 118)
Arriba filter: 229 rows -> 27 PASS; wrote tih_rna_sample_00149_B23WHTKLT4_2.arriba.fusions.filtered.tsv and tih_rna_sample_00149_B23WHTKLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00149_B23WHTKLT4_2.arriba.fusions.filter_summary.txt