Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3f/b7e8efbf9a94ee6694df3ffcff21a3/659_bhK-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/08/5c8f8ebde49b60286c9a375f137777/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/08/5c8f8ebde49b60286c9a375f137777/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 130
Pass (FILTER=PASS): 7 (5.4%)
Fail (FILTER=FAIL): 123 (94.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 24
confidence_below_min(medium<high): 23
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 9
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(low<high): 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
Breakdown by confidence:
high: 7 pass, 0 fail (total: 7)
low: 0 pass, 57 fail (total: 57)
medium: 0 pass, 66 fail (total: 66)
Arriba filter: 130 rows -> 7 PASS; wrote 659_bhK-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered.tsv and 659_bhK-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bhK-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filter_summary.txt