Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/05/0d9dd0cab367719b5505f3a0dcd443/659_dm4-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/bc/eff397800cad18adf1ab4f1e249d84/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/bc/eff397800cad18adf1ab4f1e249d84/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 3 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
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Total fusions: 34
Pass (FILTER=PASS): 11 (32.4%)
Fail (FILTER=FAIL): 23 (67.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 3
All 3 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 2
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
total_reads_below_min(7.0<8.0): 1
total_reads_below_min(3.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(3.0<8.0);aih_curated_blacklist: 1
Breakdown by confidence:
high: 11 pass, 2 fail (total: 13)
low: 0 pass, 5 fail (total: 5)
medium: 0 pass, 16 fail (total: 16)
Arriba filter: 34 rows -> 11 PASS; wrote 659_dm4-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered.tsv and 659_dm4-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_dm4-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filter_summary.txt