Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3e/b249fc8f76d18bb4decf7167a87b9d/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3e/b249fc8f76d18bb4decf7167a87b9d/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/22/f96c4fcb9312cd1918683b329a0a40/659_d01-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 104
Pass (FILTER=PASS): 5 (4.8%)
Fail (FILTER=FAIL): 99 (95.2%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 25
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(medium<high): 6
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 1
total_reads_below_min(5.0<8.0): 1
total_reads_below_min(3.0<8.0);aih_curated_blacklist: 1
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 5 pass, 2 fail (total: 7)
low: 0 pass, 51 fail (total: 51)
medium: 0 pass, 46 fail (total: 46)
Arriba filter: 104 rows -> 5 PASS; wrote 659_d01-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered.tsv and 659_d01-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_d01-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filter_summary.txt