Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/96/97124802979722f69bac3808f7b360/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0e/d3e0f0c696d2e994fed46860b7449d/659_ciZ-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/96/97124802979722f69bac3808f7b360/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 3 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 50
Pass (FILTER=PASS): 5 (10.0%)
Fail (FILTER=FAIL): 45 (90.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 3
All 3 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(medium<high): 2
total_reads_below_min(2.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 1
confidence_below_min(low<high): 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 5 pass, 1 fail (total: 6)
low: 0 pass, 33 fail (total: 33)
medium: 0 pass, 11 fail (total: 11)
Arriba filter: 50 rows -> 5 PASS; wrote 659_ciZ-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered.tsv and 659_ciZ-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_ciZ-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filter_summary.txt