Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/97/8ed4167e7cceecbc9b40da75ef6d27/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/97/8ed4167e7cceecbc9b40da75ef6d27/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9a/97aaedc1ac76fca1c2ada9f6904e70/tih_rna_sample_00473_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 179
Pass (FILTER=PASS): 13 (7.3%)
Fail (FILTER=FAIL): 166 (92.7%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 5
All 5 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 24
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 22
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 20
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 16
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 13
confidence_below_min(low<high): 11
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
total_reads_below_min(3.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 2
Breakdown by confidence:
high: 13 pass, 5 fail (total: 18)
low: 0 pass, 81 fail (total: 81)
medium: 0 pass, 80 fail (total: 80)
Arriba filter: 179 rows -> 13 PASS; wrote tih_rna_sample_00473_B23WHTKLT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00473_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00473_B23WHTKLT4_1.arriba.fusions.filter_summary.txt