Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/60/6a18b8d4f23f04cad8768d14b76c07/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/60/6a18b8d4f23f04cad8768d14b76c07/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/31/7655f14bca633605ab804862688971/659_dES-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 192
Pass (FILTER=PASS): 37 (19.3%)
Fail (FILTER=FAIL): 155 (80.7%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 6
All 6 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 24
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 20
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 15
confidence_below_min(medium<high): 14
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
total_reads_below_min(3.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 5
confidence_below_min(low<high): 5
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
total_reads_below_min(6.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 3
Breakdown by confidence:
high: 37 pass, 13 fail (total: 50)
low: 0 pass, 92 fail (total: 92)
medium: 0 pass, 50 fail (total: 50)
Arriba filter: 192 rows -> 37 PASS; wrote 659_dES-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered.tsv and 659_dES-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_dES-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filter_summary.txt