Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9c/cb72800bf0200c7097d2d8e8aeacc8/tih_rna_sample_00434_B23WHTKLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/39/54de8527e7537788f5dd14f8d98537/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/39/54de8527e7537788f5dd14f8d98537/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 157
  Pass (FILTER=PASS): 19 (12.1%)
  Fail (FILTER=FAIL): 138 (87.9%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 6
  All 6 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 59
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 15
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
  confidence_below_min(low<high): 8
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 3
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0);aih_curated_blacklist: 1
  total_reads_below_min(3.0<8.0): 1
  confidence_below_min(low<high);aih_curated_blacklist: 1

Breakdown by confidence:
  high: 19 pass, 1 fail (total: 20)
  low: 0 pass, 51 fail (total: 51)
  medium: 0 pass, 86 fail (total: 86)
Arriba filter: 157 rows -> 19 PASS; wrote tih_rna_sample_00434_B23WHTKLT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00434_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00434_B23WHTKLT4_1.arriba.fusions.filter_summary.txt