Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/36/042346f88115c865734aee188ecdec/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/36/042346f88115c865734aee188ecdec/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/09/2f3689e4d50ae898b1e1fa06b325ea/tih_rna_sample_00457_B23WHTKLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-99ebc9bd-f9f1-4b2c-b9a0-02ddaf99f257/ee/adda01b2d23fdd27de06edfd21ea26/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 15 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 227
  Pass (FILTER=PASS): 21 (9.3%)
  Fail (FILTER=FAIL): 206 (90.7%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 15
  All 15 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 60
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 30
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 27
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 14
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 6
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 5
  confidence_below_min(medium<high);aih_curated_blacklist: 5
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 5
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 5
  confidence_below_min(low<high): 4
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3

Breakdown by confidence:
  high: 21 pass, 7 fail (total: 28)
  low: 0 pass, 78 fail (total: 78)
  medium: 0 pass, 121 fail (total: 121)
Arriba filter: 227 rows -> 21 PASS; wrote tih_rna_sample_00457_B23WHTKLT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00457_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00457_B23WHTKLT4_1.arriba.fusions.filter_summary.txt