Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/51/ecd07bea199fb193499e115d0fab21/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/51/ecd07bea199fb193499e115d0fab21/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ac/2d574231ca6467ae3edbaf75873ca5/659_cIX-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-6a8e5f46-8592-47ae-b09e-a1efe7f02cb2/6a/80a8f8c27f6b00a3a33e35ea914965/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 4 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 135
Pass (FILTER=PASS): 15 (11.1%)
Fail (FILTER=FAIL): 120 (88.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 4
All 4 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 29
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 13
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 8
confidence_below_min(low<high): 7
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 3
total_reads_below_min(3.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0);aih_curated_blacklist: 2
aih_curated_blacklist: 1
Breakdown by confidence:
high: 15 pass, 7 fail (total: 22)
low: 0 pass, 49 fail (total: 49)
medium: 0 pass, 64 fail (total: 64)
Arriba filter: 135 rows -> 15 PASS; wrote 659_cIX-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered.tsv and 659_cIX-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_cIX-T1-TRNA-1_B23WHTKLT4_1.arriba.fusions.filter_summary.txt