Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/40/98cd276ec5ad131043e8151bd0cddb/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/40/98cd276ec5ad131043e8151bd0cddb/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/8d/d232321c5cebe1894af9202d3e0aea/tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-6a8e5f46-8592-47ae-b09e-a1efe7f02cb2/6a/80a8f8c27f6b00a3a33e35ea914965/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 4 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 62
Pass (FILTER=PASS): 2 (3.2%)
Fail (FILTER=FAIL): 60 (96.8%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 4
All 4 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 7
confidence_below_min(low<high): 6
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 5
confidence_below_min(medium<high): 4
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 1
Breakdown by confidence:
high: 2 pass, 0 fail (total: 2)
low: 0 pass, 40 fail (total: 40)
medium: 0 pass, 20 fail (total: 20)
Arriba filter: 62 rows -> 2 PASS; wrote tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.filtered.tsv and tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00090_B23WHTKLT4_2.arriba.fusions.filter_summary.txt