Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/38/0f54c98c61207c4a03769dad3276fc/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/38/0f54c98c61207c4a03769dad3276fc/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/46/5fc9c78cf5c4e3110472435a10d992/aih-tih-sc-5b8b4a-R1_A23YTGFLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-eb5d3959-7137-45a9-9f26-41f9201dcf7f/81/be38f7f47cc30e4a107d9e602cb8fb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 218
Pass (FILTER=PASS): 6 (2.8%)
Fail (FILTER=FAIL): 212 (97.2%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 6
All 6 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 50
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 36
confidence_below_min(low<high): 24
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 17
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 13
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
total_reads_below_min(3.0<8.0): 2
Breakdown by confidence:
high: 6 pass, 5 fail (total: 11)
low: 0 pass, 95 fail (total: 95)
medium: 0 pass, 112 fail (total: 112)
Arriba filter: 218 rows -> 6 PASS; wrote aih-tih-sc-5b8b4a-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-5b8b4a-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-5b8b4a-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt