Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/38/5d5e24b851e83b7e8c7cb4c3b31dbf/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/38/5d5e24b851e83b7e8c7cb4c3b31dbf/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fd/7a03603c1b7fe130287f05fdba9e95/aih-tih-sc-9b89b4-R1_A23YTGFLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-eb5d3959-7137-45a9-9f26-41f9201dcf7f/81/be38f7f47cc30e4a107d9e602cb8fb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 15 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 316
Pass (FILTER=PASS): 36 (11.4%)
Fail (FILTER=FAIL): 280 (88.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 15
All 15 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 93
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 30
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 21
confidence_below_min(low<high): 20
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 19
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 18
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 5
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
Breakdown by confidence:
high: 36 pass, 5 fail (total: 41)
low: 0 pass, 124 fail (total: 124)
medium: 0 pass, 151 fail (total: 151)
Arriba filter: 316 rows -> 36 PASS; wrote aih-tih-sc-9b89b4-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-9b89b4-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-9b89b4-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt