Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f7/41cb4312f3c4c3604f1dbd6d261861/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/73/98ac38db28c64c0a02f0e53ec5aba8/aih-tih-sc-d963a2-R1_A23YTGFLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f7/41cb4312f3c4c3604f1dbd6d261861/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-eb5d3959-7137-45a9-9f26-41f9201dcf7f/81/be38f7f47cc30e4a107d9e602cb8fb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 198
Pass (FILTER=PASS): 13 (6.6%)
Fail (FILTER=FAIL): 185 (93.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 9
All 9 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 31
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 24
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 22
confidence_below_min(low<high): 20
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 6
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
Breakdown by confidence:
high: 13 pass, 5 fail (total: 18)
low: 0 pass, 101 fail (total: 101)
medium: 0 pass, 79 fail (total: 79)
Arriba filter: 198 rows -> 13 PASS; wrote aih-tih-sc-d963a2-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-d963a2-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-d963a2-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt