Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f9/d83733c56609e2a043b6edacd7df4d/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f9/d83733c56609e2a043b6edacd7df4d/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/7c/1bfc75ad0e3fefff57ced55d3d2945/aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-eb5d3959-7137-45a9-9f26-41f9201dcf7f/81/be38f7f47cc30e4a107d9e602cb8fb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 282
Pass (FILTER=PASS): 47 (16.7%)
Fail (FILTER=FAIL): 235 (83.3%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 12
All 12 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 44
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 31
confidence_below_min(low<high): 25
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 22
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 19
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 16
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 5
total_reads_below_min(4.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 5
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
Breakdown by confidence:
high: 47 pass, 11 fail (total: 58)
low: 0 pass, 125 fail (total: 125)
medium: 0 pass, 99 fail (total: 99)
Arriba filter: 282 rows -> 47 PASS; wrote aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt