Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/da/6cd73aeeb1baca2744604ca011b356/aih-tih-sc-377071-R1_A23YTGFLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0d/d4fc1a4f0a6f11257a8ad4e49669e9/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0d/d4fc1a4f0a6f11257a8ad4e49669e9/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-eb5d3959-7137-45a9-9f26-41f9201dcf7f/81/be38f7f47cc30e4a107d9e602cb8fb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 277
  Pass (FILTER=PASS): 74 (26.7%)
  Fail (FILTER=FAIL): 203 (73.3%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 7
  All 7 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 42
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 23
  confidence_below_min(low<high): 21
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 19
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 14
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 12
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 7
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 5
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
  total_reads_below_min(7.0<8.0): 2

Breakdown by confidence:
  high: 74 pass, 6 fail (total: 80)
  low: 0 pass, 95 fail (total: 95)
  medium: 0 pass, 102 fail (total: 102)
Arriba filter: 277 rows -> 74 PASS; wrote aih-tih-sc-377071-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-377071-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-377071-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt