Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a5/56a4dc4852003b823454d7ef326bcb/aih-tih-sc-e1cae1-R1_A23YTGFLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4f/df3fb297a394085e18ab2be2d5ce14/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4f/df3fb297a394085e18ab2be2d5ce14/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-e543dae6-5fea-4720-bfb6-150bf1ff20d4/33/a04540cea7c8abc13163bc03b147d5/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 63
Pass (FILTER=PASS): 3 (4.8%)
Fail (FILTER=FAIL): 60 (95.2%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 6
All 6 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high): 17
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 6
confidence_below_min(medium<high): 5
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 1
total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0);aih_curated_blacklist: 1
Breakdown by confidence:
high: 3 pass, 1 fail (total: 4)
low: 0 pass, 38 fail (total: 38)
medium: 0 pass, 21 fail (total: 21)
Arriba filter: 63 rows -> 3 PASS; wrote aih-tih-sc-e1cae1-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-e1cae1-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-e1cae1-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt