File Info

Filename
.command.log
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9b/32013a29e3ee7a891f3190d9cccd22/.command.log
Size
2.5 KB
Attempt
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9b/32013a29e3ee7a891f3190d9cccd22/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9b/32013a29e3ee7a891f3190d9cccd22/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f1/c9465a74af50aa90b06e4f4c7c7b4c/aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-e543dae6-5fea-4720-bfb6-150bf1ff20d4/33/a04540cea7c8abc13163bc03b147d5/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 282
  Pass (FILTER=PASS): 47 (16.7%)
  Fail (FILTER=FAIL): 235 (83.3%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 44
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 31
  confidence_below_min(low<high): 25
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 22
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 19
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 16
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 5
  total_reads_below_min(4.0<8.0): 5
  confidence_below_min(medium<high);aih_curated_blacklist: 5
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3

Breakdown by confidence:
  high: 47 pass, 11 fail (total: 58)
  low: 0 pass, 125 fail (total: 125)
  medium: 0 pass, 99 fail (total: 99)
Arriba filter: 282 rows -> 47 PASS; wrote aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-01c779-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt