Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e7/0905a8ba86ca5ac8e4dafcbea6ddb1/aih-tih-sc-96d0f6-R1_A23YTGFLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/27/a0df77003fbbb2739528f904a77ee0/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/27/a0df77003fbbb2739528f904a77ee0/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-e543dae6-5fea-4720-bfb6-150bf1ff20d4/33/a04540cea7c8abc13163bc03b147d5/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 188
  Pass (FILTER=PASS): 5 (2.7%)
  Fail (FILTER=FAIL): 183 (97.3%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 69
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 19
  confidence_below_min(low<high): 16
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 14
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 6
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);aih_curated_blacklist: 3
  total_reads_below_min(7.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0);aih_curated_blacklist: 2

Breakdown by confidence:
  high: 5 pass, 3 fail (total: 8)
  low: 0 pass, 82 fail (total: 82)
  medium: 0 pass, 98 fail (total: 98)
Arriba filter: 188 rows -> 5 PASS; wrote aih-tih-sc-96d0f6-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-96d0f6-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-96d0f6-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt