Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/47/53becb72075753b49cd0d068f9f1df/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/47/53becb72075753b49cd0d068f9f1df/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/00/836b174f223a105e27a902db4278df/aih-tih-sc-89f3a3-R1_A23YTGFLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-e543dae6-5fea-4720-bfb6-150bf1ff20d4/33/a04540cea7c8abc13163bc03b147d5/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 14 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 320
Pass (FILTER=PASS): 42 (13.1%)
Fail (FILTER=FAIL): 278 (86.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 14
All 14 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 68
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 25
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 24
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 23
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 21
confidence_below_min(low<high): 18
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 12
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 5
Breakdown by confidence:
high: 42 pass, 4 fail (total: 46)
low: 0 pass, 118 fail (total: 118)
medium: 0 pass, 156 fail (total: 156)
Arriba filter: 320 rows -> 42 PASS; wrote aih-tih-sc-89f3a3-R1_A23YTGFLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-89f3a3-R1_A23YTGFLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-89f3a3-R1_A23YTGFLT4_1.arriba.fusions.filter_summary.txt