Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c6/98cf6cdfd05c8336b7cfbf3d3c3f0e/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c6/98cf6cdfd05c8336b7cfbf3d3c3f0e/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/58/4f821263d1464e38d93b1e7f3f4bba/659_eZ4-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-40cc52c0-5bec-40b6-b04d-c64c51f55eff/cf/a844d18c3db3aeda7471fb3d005c4f/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 251
  Pass (FILTER=PASS): 34 (13.5%)
  Fail (FILTER=FAIL): 217 (86.5%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 7
  All 7 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 66
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 30
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 15
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 13
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
  confidence_below_min(low<high): 9
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 5
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 5
  total_reads_below_min(3.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4

Breakdown by confidence:
  high: 34 pass, 6 fail (total: 40)
  low: 0 pass, 85 fail (total: 85)
  medium: 0 pass, 126 fail (total: 126)
Arriba filter: 251 rows -> 34 PASS; wrote 659_eZ4-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_eZ4-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_eZ4-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt