Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3d/d2f3887ac6b75544fa3cce431b08a5/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3d/d2f3887ac6b75544fa3cce431b08a5/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9a/2bc871eb394cf809828e0bc439307d/659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-40cc52c0-5bec-40b6-b04d-c64c51f55eff/cf/a844d18c3db3aeda7471fb3d005c4f/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 391
  Pass (FILTER=PASS): 36 (9.2%)
  Fail (FILTER=FAIL): 355 (90.8%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 119
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 59
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 24
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 22
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 19
  confidence_below_min(low<high): 16
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 14
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 14
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 9
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
  confidence_below_min(medium<high);aih_curated_blacklist: 7
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4

Breakdown by confidence:
  high: 36 pass, 5 fail (total: 41)
  low: 0 pass, 154 fail (total: 154)
  medium: 0 pass, 196 fail (total: 196)
Arriba filter: 391 rows -> 36 PASS; wrote 659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt