Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/00/a802164e73336ae491eb48a8f96f70/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/00/a802164e73336ae491eb48a8f96f70/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a8/2016eae0975742867236efde4581d6/659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-40cc52c0-5bec-40b6-b04d-c64c51f55eff/cf/a844d18c3db3aeda7471fb3d005c4f/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 18 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 342
Pass (FILTER=PASS): 89 (26.0%)
Fail (FILTER=FAIL): 253 (74.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 18
All 18 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 68
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 40
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 22
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 19
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(low<high): 12
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(medium<high);aih_curated_blacklist: 8
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
total_reads_below_min(5.0<8.0): 3
Breakdown by confidence:
high: 89 pass, 6 fail (total: 95)
low: 0 pass, 121 fail (total: 121)
medium: 0 pass, 126 fail (total: 126)
Arriba filter: 342 rows -> 89 PASS; wrote 659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt