Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d0/b13ce5d69c9b09b8b65b3c5563fd6d/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d0/b13ce5d69c9b09b8b65b3c5563fd6d/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/60/b6a6af362bb997ed24c529293fd5ea/659_dts-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 270
Pass (FILTER=PASS): 26 (9.6%)
Fail (FILTER=FAIL): 244 (90.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 97
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 33
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 17
confidence_below_min(low<high): 14
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(low<high);aih_curated_blacklist: 2
Breakdown by confidence:
high: 26 pass, 2 fail (total: 28)
low: 0 pass, 110 fail (total: 110)
medium: 0 pass, 132 fail (total: 132)
Arriba filter: 270 rows -> 26 PASS; wrote 659_dts-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_dts-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_dts-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt