Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2f/5af2a623cfb5e3af6870ef72ead83b/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2f/5af2a623cfb5e3af6870ef72ead83b/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/33/e5c881bd06f97479e7b4ac47909d3d/659_eGK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 338
Pass (FILTER=PASS): 55 (16.3%)
Fail (FILTER=FAIL): 283 (83.7%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 97
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 38
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 24
confidence_below_min(low<high): 23
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 9
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(low<high);aih_curated_blacklist: 3
Breakdown by confidence:
high: 55 pass, 5 fail (total: 60)
low: 0 pass, 145 fail (total: 145)
medium: 0 pass, 133 fail (total: 133)
Arriba filter: 338 rows -> 55 PASS; wrote 659_eGK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_eGK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_eGK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt