Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b9/fea2dba6c6c22c717cd358b8032a11/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b9/fea2dba6c6c22c717cd358b8032a11/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a8/90a451716b69def6b8ad6374e8aff3/659_Fr-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 11 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 296
Pass (FILTER=PASS): 70 (23.6%)
Fail (FILTER=FAIL): 226 (76.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 11
All 11 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 69
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 35
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 20
confidence_below_min(low<high): 17
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(medium<high);aih_curated_blacklist: 6
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
Breakdown by confidence:
high: 70 pass, 5 fail (total: 75)
low: 0 pass, 114 fail (total: 114)
medium: 0 pass, 107 fail (total: 107)
Arriba filter: 296 rows -> 70 PASS; wrote 659_Fr-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_Fr-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_Fr-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt