Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fb/10b5cea2637519adc63d42e727fff3/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fb/10b5cea2637519adc63d42e727fff3/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/61/b6cd21204845a2a8202a59e6e59e6b/659_ezg-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 11 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 272
Pass (FILTER=PASS): 18 (6.6%)
Fail (FILTER=FAIL): 254 (93.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 11
All 11 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 68
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 58
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 18
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 16
confidence_below_min(low<high): 15
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 6
confidence_below_min(medium<high);aih_curated_blacklist: 6
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
Breakdown by confidence:
high: 18 pass, 2 fail (total: 20)
low: 0 pass, 130 fail (total: 130)
medium: 0 pass, 122 fail (total: 122)
Arriba filter: 272 rows -> 18 PASS; wrote 659_ezg-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_ezg-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_ezg-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt