Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cf/c0424493f1236c20833187f5d61d82/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cf/c0424493f1236c20833187f5d61d82/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/16/2a837f8f3749c95723b9ae4b6595ef/659_bTq-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 322
Pass (FILTER=PASS): 36 (11.2%)
Fail (FILTER=FAIL): 286 (88.8%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 12
All 12 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 93
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 35
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 16
confidence_below_min(low<high): 16
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 16
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 15
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 5
total_reads_below_min(5.0<8.0): 2
Breakdown by confidence:
high: 36 pass, 8 fail (total: 44)
low: 0 pass, 134 fail (total: 134)
medium: 0 pass, 144 fail (total: 144)
Arriba filter: 322 rows -> 36 PASS; wrote 659_bTq-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_bTq-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bTq-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt