Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4f/5016cccde874f3007fe6ec7f66d7de/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4f/5016cccde874f3007fe6ec7f66d7de/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b9/6e535fcf8ad33664e7f269b0e8fcd8/659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 18 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 342
Pass (FILTER=PASS): 89 (26.0%)
Fail (FILTER=FAIL): 253 (74.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 18
All 18 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 68
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 40
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 22
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 19
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(low<high): 12
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(medium<high);aih_curated_blacklist: 8
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
total_reads_below_min(5.0<8.0): 3
Breakdown by confidence:
high: 89 pass, 6 fail (total: 95)
low: 0 pass, 121 fail (total: 121)
medium: 0 pass, 126 fail (total: 126)
Arriba filter: 342 rows -> 89 PASS; wrote 659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bUs-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt