Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d0/1f4f30b336934336dd8e06d61e068b/659_bNS-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2f/7f90f4395412b2f2d06947aa90ea3d/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2f/7f90f4395412b2f2d06947aa90ea3d/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 230
Pass (FILTER=PASS): 50 (21.7%)
Fail (FILTER=FAIL): 180 (78.3%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 12
All 12 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 57
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 12
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(low<high): 8
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(low<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
Breakdown by confidence:
high: 50 pass, 4 fail (total: 54)
low: 0 pass, 87 fail (total: 87)
medium: 0 pass, 89 fail (total: 89)
Arriba filter: 230 rows -> 50 PASS; wrote 659_bNS-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_bNS-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bNS-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt