Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/dc/f3262b890402aa7360699fcf54d03c/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/dc/f3262b890402aa7360699fcf54d03c/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/19/882cee40d5b9ebf55f755bd86244b4/659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 391
Pass (FILTER=PASS): 36 (9.2%)
Fail (FILTER=FAIL): 355 (90.8%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 12
All 12 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 119
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 59
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 24
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 22
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 19
confidence_below_min(low<high): 16
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
confidence_below_min(medium<high);aih_curated_blacklist: 7
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
Breakdown by confidence:
high: 36 pass, 5 fail (total: 41)
low: 0 pass, 154 fail (total: 154)
medium: 0 pass, 196 fail (total: 196)
Arriba filter: 391 rows -> 36 PASS; wrote 659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_dHy-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt