Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0f/e4fb580ba8bf0bdae65a348c367a04/659_bUW-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b6/841735a7707f9ae2cb69fac5051eb8/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b6/841735a7707f9ae2cb69fac5051eb8/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 253
Pass (FILTER=PASS): 9 (3.6%)
Fail (FILTER=FAIL): 244 (96.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 9
All 9 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 46
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 38
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 28
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 22
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 21
confidence_below_min(low<high): 17
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 2
Breakdown by confidence:
high: 9 pass, 2 fail (total: 11)
low: 0 pass, 130 fail (total: 130)
medium: 0 pass, 112 fail (total: 112)
Arriba filter: 253 rows -> 9 PASS; wrote 659_bUW-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_bUW-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bUW-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt