Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/80/614cb93dbea70edd2f4b11de77dd38/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/80/614cb93dbea70edd2f4b11de77dd38/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3f/9b89c61ec0d0d6c80124fb6191733c/659_cB6-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 125
Pass (FILTER=PASS): 22 (17.6%)
Fail (FILTER=FAIL): 103 (82.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 5
All 5 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 25
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 5
total_reads_below_min(4.0<8.0): 3
total_reads_below_min(3.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
total_reads_below_min(6.0<8.0): 2
total_reads_below_min(5.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 2
Breakdown by confidence:
high: 22 pass, 12 fail (total: 34)
low: 0 pass, 38 fail (total: 38)
medium: 0 pass, 53 fail (total: 53)
Arriba filter: 125 rows -> 22 PASS; wrote 659_cB6-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_cB6-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_cB6-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt