Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e1/55af9d17c7b420eeb3c32ef901fdd3/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e1/55af9d17c7b420eeb3c32ef901fdd3/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9e/2bd3f815e34fbccd150de02f04f55b/659_gK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-0c31b8cc-cacb-407a-8f2b-eb2d8317e249/e8/83b3d86dc9f1df6763490ba67ef20d/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 11 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 204
Pass (FILTER=PASS): 15 (7.4%)
Fail (FILTER=FAIL): 189 (92.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 11
All 11 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 41
confidence_below_min(medium<high): 28
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 18
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 13
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(low<high): 8
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
Breakdown by confidence:
high: 15 pass, 3 fail (total: 18)
low: 0 pass, 109 fail (total: 109)
medium: 0 pass, 77 fail (total: 77)
Arriba filter: 204 rows -> 15 PASS; wrote 659_gK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered.tsv and 659_gK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_gK-T1-TRNA-1_B23MHV2LT4_1.arriba.fusions.filter_summary.txt