Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/foresight_panel_for_manta.bed Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4e/82af65452445e6b252c3eebbaa2b9b/.command.sh Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/protein_coding_genes.bed Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/41/fffb646dbc5138d457ad0e0feab8bf/659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.annotated.vcf.gz.tbi Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/41/fffb646dbc5138d457ad0e0feab8bf/659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.annotated.vcf.gz Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/model.pkl Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4e/82af65452445e6b252c3eebbaa2b9b/.command.run Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/cosmic_fusion.tsv.gz Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/pon ==> STAGING COMPLETE (9 inputs) [predict] Loading model from model.pkl … 36 features loaded [predict] Loading PoN from pon … 1D bins: 43,871 2D pairs: 39,238 [predict] Loading COSMIC from cosmic_fusion.tsv.gz … 614 gene-pair orientations [predict] Loading gene annotator from protein_coding_genes.bed … [predict] Loading target panel from foresight_panel_for_manta.bed … 201,779 panel intervals across 26 contigs [predict] Tumor sample ID: '659_eHw-T1-TDNA-1_B23MCVGLT4_1' Normal sample ID: '659_eHw-N1-BDNA-1_B23KFG5LT4_1' [predict] Parsing VCF 659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.annotated.vcf.gz … 12 calls parsed (after intergenic/same-gene/on_panel filter) 8 killed by hard filters → 4 surviving is_paralog_of_higher_score_call=1 for 0/4 calls [predict] Scored 4 calls: 2 PASS at threshold 0.15 After events_match dedup: 4 calls (2 PASS) Final call set: 4 calls (2 PASS) [predict] Writing 659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.scored.vcf.gz … [predict] Writing 659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.fusion_calls.tsv … [predict] Done.