mkdir -p failed for path /.config/matplotlib: [Errno 13] Permission denied: '/.config'
Matplotlib created a temporary cache directory at /tmp/matplotlib-hs6v7mcf because there was an issue with the default path (/.config/matplotlib); it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
2026-06-03 04:56:06,165 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Load count data for processing
2026-06-03 04:57:15,603 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Data loaded
2026-06-03 04:57:15,643 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Find low probe mask, low sample mask, and 2D outlier mask. Autosomes only.
2026-06-03 04:57:15,918 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 3723072
2026-06-03 04:57:38,995 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 1240933
2026-06-03 04:57:58,926 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 199029
2026-06-03 04:58:19,476 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 112052
2026-06-03 04:58:39,747 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 72878
2026-06-03 04:58:59,613 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 53374
2026-06-03 04:59:19,847 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 43300
2026-06-03 04:59:40,169 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 37065
2026-06-03 04:59:59,802 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 33306
2026-06-03 05:00:18,883 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 31440
2026-06-03 05:00:38,126 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 29875
2026-06-03 05:00:56,472 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 29390
2026-06-03 05:01:14,439 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 28585
2026-06-03 05:01:32,782 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 28574
2026-06-03 05:01:50,961 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 28786
2026-06-03 05:02:10,640 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 29596
2026-06-03 05:02:30,339 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 16, outliers: 30642
2026-06-03 05:02:49,365 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 17, outliers: 31131
2026-06-03 05:03:09,453 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 18, outliers: 32966
2026-06-03 05:03:31,214 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 19, outliers: 35027
2026-06-03 05:03:53,108 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 20, outliers: 38223
2026-06-03 05:04:14,341 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 21, outliers: 42313
2026-06-03 05:04:36,123 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 22, outliers: 48535
2026-06-03 05:04:57,684 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 23, outliers: 58164
2026-06-03 05:05:19,278 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 24, outliers: 57415
2026-06-03 05:05:42,191 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks obtained
2026-06-03 05:05:42,191 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Correct counts based on melting temperature
2026-06-03 05:05:58,728 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Corrected counts obtained
2026-06-03 05:05:58,728 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Refind masks with melting-temperature corrected counts. Autosomes only.
2026-06-03 05:05:59,054 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 3723072
2026-06-03 05:06:30,734 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 1217287
2026-06-03 05:06:55,636 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 196708
2026-06-03 05:07:21,384 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 112062
2026-06-03 05:07:46,892 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 73452
2026-06-03 05:08:12,539 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 54171
2026-06-03 05:08:38,463 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 43832
2026-06-03 05:09:03,753 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 37856
2026-06-03 05:09:29,248 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 34196
2026-06-03 05:09:55,784 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 32090
2026-06-03 05:10:22,453 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 30824
2026-06-03 05:10:48,020 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 30037
2026-06-03 05:11:12,054 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 29646
2026-06-03 05:11:37,056 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 29402
2026-06-03 05:12:01,065 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 30280
2026-06-03 05:12:24,563 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 30758
2026-06-03 05:12:49,536 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 16, outliers: 31952
2026-06-03 05:13:13,701 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 17, outliers: 32888
2026-06-03 05:13:37,664 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 18, outliers: 34923
2026-06-03 05:14:01,416 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 19, outliers: 37407
2026-06-03 05:14:25,167 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 20, outliers: 40671
2026-06-03 05:14:48,865 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 21, outliers: 45873
2026-06-03 05:15:11,935 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 22, outliers: 54078
2026-06-03 05:15:34,294 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 23, outliers: 63934
2026-06-03 05:15:56,229 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 24, outliers: 48417
2026-06-03 05:16:18,297 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks obtained, from melting-temperature corrected counts
2026-06-03 05:16:18,299 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Redo melting-temperature correction with new masks
2026-06-03 05:18:16,924 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Corrected counts obtained, using second round of masks
2026-06-03 05:18:16,924 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get effective sample size per probe from covariance of nearby probes, autosomes
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.384703393580452 > -120.314509671532448). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.384703393580452 > -120.314509671532448). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.384703393580452 > -120.314509671532448). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.384703393580452 > -120.314509671532448). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.384703393580452 > -120.314509671532448). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.384703393580452 > -120.314509671532448). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.790581812466050 > -41.236121733348867). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.790581812466050 > -41.236121733348867). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.790581812466050 > -41.236121733348867). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.790581812466050 > -41.236121733348867). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-91.980725158409896 > -125.164262013353635). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-94.221335036228908 > -127.765560538891961). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-94.221335036228908 > -127.765560538891961). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.148315494487306 > -117.481430726641563). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.642102303410127 > -116.463439801795687). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-84.454106227436455 > -147.271991678182246). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-79.865986990239875 > -152.268060746611695). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-79.606206888047652 > -153.003293556338917). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-79.606206888047652 > -153.003293556338917). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-57.265556922636208 > -127.915411403615309). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-57.265556922636208 > -127.915411403615309). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-71.201857762313779 > -107.469316814354215). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-71.305709300711300 > -108.315514523017043). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-76.099459559274763 > -143.500892443421947). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-85.891927476627572 > -162.393419856444865). You may want to try with a higher value of support_fraction (current value: 0.544).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-87.622825387855784 > -161.126641499201014). You may want to try with a higher value of support_fraction (current value: 0.544).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-91.106741152461211 > -121.463134347354369). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.657263621652902 > -120.406086150030987). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.870840074634245 > -120.429319406485803). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-91.106741152461268 > -121.396851901392097). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-91.106741152461254 > -121.407871463589572). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.939983420091693 > -121.220379474903652). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-91.106741152461211 > -121.463134347354369). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.137686292229205 > -113.141977501358028). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.726976572839874 > -134.050625099035813). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.501559947555805 > -135.499941914626476). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.416619842356582 > -131.128325035501348). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.468990816609320 > -134.013128083054141). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.416619842356582 > -130.394789103972045). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.709096204748505 > -137.487491606318258). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.709096204748505 > -137.487491606318258). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.730694476830749 > -135.885088817612314). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.544297228566094 > -130.136661643984269). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.544297228566094 > -129.962317941333765). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.544297228566094 > -129.962317941333765). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.544297228566094 > -130.136661643984269). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.544297228566094 > -130.136661643984269). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.654882385773689). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.372649918089493). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.372649918089493). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.494539735704137). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.654882385773689). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.654882385773689). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.654882385773689). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.586440871583633 > -108.654882385773689). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-77.295738102748629 > -205.166361862886504). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-77.295738102748629 > -205.166361862886504). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-77.295738102748629 > -205.166361862886504). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-77.295738102748629 > -205.166361862886504). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-141.833028513402326 > -143.959141546032726). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.605456675528501 > -168.504145873258352). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.265221669152680 > -77.946850701516027). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.265221669152680 > -77.946850701516027). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.265221669152680 > -77.946850701516027). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.265221669152680 > -77.946850701516027). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-51.211681576251024 > -104.319268629092548). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-51.211681576251024 > -104.319268629092548). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-51.211681576251024 > -104.319268629092548). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-51.211681576251024 > -104.319268629092548). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-61.803991894698534 > -62.140464131319746). You may want to try with a higher value of support_fraction (current value: 0.518).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.280098693672926). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.921436024857627). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.280098693672926). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.921436024857627). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.921436024857627). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.280098693672926). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.280098693672898). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.280098693672926). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -117.446058266820984). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.386945937718664 > -118.280098693672926). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.149867664161128 > -119.145782558654730). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.187413269678167 > -116.392032399669233). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.110649518515295 > -116.258191482718729). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.187413269678167 > -116.392032399669233). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.110649518515295 > -116.258191482718729). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.187413269678167 > -116.392032399669233). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.110649518515295 > -116.258191482718729). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.187413269678167 > -116.392032399669233). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.110649518515295 > -116.258191482718729). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.187413269678167 > -116.392032399669233). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-54.110649518515295 > -116.258191482718729). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.249156950874877 > -114.832030666243895). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.604514463060912 > -45.165986170930239). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-43.874256220216083 > -43.875366714500103). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-43.874256220216083 > -43.875366714500103). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-43.874256220216083 > -43.875366714500103). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-43.874256220216083 > -43.875366714500103). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-352.804396295874483 > -353.210711968873113). You may want to try with a higher value of support_fraction (current value: 0.547).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-327.680034858361296 > -358.461114522690877). You may want to try with a higher value of support_fraction (current value: 0.553).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-115.217606518695135 > -169.852992533643373). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-118.714605005940285 > -173.383123241597417). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-146.464624761902769 > -170.391419607183337). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-118.714605005940285 > -173.383123241597417). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-115.217606518695135 > -169.852992533643373). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-139.377444355474324 > -139.888269979240818). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-133.133673802888353 > -235.526500367999091). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.214428457329532 > -179.689102881653582). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.393628335447630 > -149.132310316807775). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-119.686997860540231 > -146.319106757124615). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-119.686997860540231 > -146.319106757124615). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-89.307868216384350 > -149.571300820187759). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-123.223594166970145 > -124.457698014959632). You may want to try with a higher value of support_fraction (current value: 0.545).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-123.223594166970145 > -124.457698014959632). You may want to try with a higher value of support_fraction (current value: 0.545).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-123.223594166970145 > -124.457698014959632). You may want to try with a higher value of support_fraction (current value: 0.545).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-123.223594166970145 > -124.457698014959632). You may want to try with a higher value of support_fraction (current value: 0.545).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.039194706513038 > -41.366981501293218). You may want to try with a higher value of support_fraction (current value: 0.513).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.039194706513038 > -41.366981501293218). You may want to try with a higher value of support_fraction (current value: 0.513).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.039194706513038 > -41.366981501293218). You may want to try with a higher value of support_fraction (current value: 0.513).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.356985964891559 > -42.719574928606598). You may want to try with a higher value of support_fraction (current value: 0.511).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-161.108765947910399 > -162.284587122893441). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-161.108765947910399 > -162.284587122893441). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-154.056816870837224 > -314.461543310299589). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-142.988815759886279 > -143.282332785604041). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-143.229624263046787 > -158.877408942684212). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-143.783286613229876 > -145.173225781856019). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-143.229624263046787 > -158.701007598445671). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-142.988815759886279 > -143.525457388109032). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-175.523818041954144 > -175.638079560440417). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-170.799999022090503 > -171.808698077601150). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-175.523818041954144 > -175.638079560440417). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-170.799999022090503 > -171.808698077601150). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-217.069693299282505 > -217.304015883260803). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-217.069693299282505 > -217.304015883260803). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-301.395139583094988 > -302.495572126481932). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-398.740025983862154 > -421.765986259233728). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-369.166422058195565 > -371.455927175441161). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-301.395139583094988 > -302.495572126481932). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-398.740025983862154 > -421.765986259233728). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-369.166422058195565 > -371.455927175441161). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-186.440202994645176 > -187.159510836047417). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-189.558133118096748 > -190.154623330589914). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.259071767859794 > -89.467421540974527). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.259071767858131 > -90.175273962404617). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.259071767859794 > -89.467421540974527). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.259071767858131 > -90.175273962404617). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-100.159344330222865 > -100.698364627546482). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.751728259740588 > -167.138917410774042). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.492537224394368 > -160.869631583715062). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-108.873900522454349 > -166.702498766500696). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-108.873900522454349 > -166.702498766500696). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-108.873900522454349 > -166.702498766500696). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-109.111702740263922 > -138.184899019200287). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-171.051728948586003 > -242.063055309470798). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-170.793632661739679 > -240.230226688271415). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-173.153385932303024 > -275.939442180742276). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.921781979493176 > -191.114174838933536). You may want to try with a higher value of support_fraction (current value: 0.562).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-95.886890803415412 > -142.634384317470506). You may want to try with a higher value of support_fraction (current value: 0.566).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-146.807536547974678 > -147.958973423960089). You may want to try with a higher value of support_fraction (current value: 0.566).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-55.551064034806437 > -122.995156990368258). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-94.838406588222853 > -158.453614495783796). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-89.497498784590519 > -188.196310338284491). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.141194301853503 > -123.976085246812687). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.240123121703007 > -117.990421870610106). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.748589402851039 > -150.562562082474813). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-121.889163066412110 > -150.553203528323166). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.055476103271417 > -150.087132673767513). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.058786642344103 > -149.909589541850096). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.748589402851039 > -150.562562082474813). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.748589402851039 > -150.562562082474813). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.402897866476209 > -150.987766167913037). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-128.013338299607170 > -156.895921411954305). You may want to try with a higher value of support_fraction (current value: 0.555).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-127.802718102520132 > -155.492329282791559). You may want to try with a higher value of support_fraction (current value: 0.555).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-113.574722909229322 > -145.753540326296843). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-119.747624008197647 > -145.104699554122419). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-121.258498360839837 > -148.891594048276772). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-123.128517656211145 > -182.856828281058313). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-110.569520902834839 > -176.701493596571680). You may want to try with a higher value of support_fraction (current value: 0.560).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.425967472435502 > -182.975019534015075). You may want to try with a higher value of support_fraction (current value: 0.560).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-113.410499884056236 > -187.082550244252673). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-113.249028440478654 > -149.701586426292181). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.891001991662435 > -186.846558672428500). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.810976117432901 > -149.454927733713077). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-107.028583220661830 > -177.286354870117350). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-106.599961251395172 > -178.165780854010734). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-106.859859719788460 > -178.779725102186831). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-102.309478427826548 > -131.130389457742382). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.842398962800644 > -133.319575199937560). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.970251439852177 > -131.747840850777607). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.895184986986081 > -139.129536290805078). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-102.147941152944099 > -132.302898068773118). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.842398962800644 > -133.319575199937560). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.823968667576324 > -137.265910385108782). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.888265130319240 > -171.139017775079139). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.670327195897883 > -167.656582975048138). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-97.484166363708653 > -165.204702535887463). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.062140659474693 > -164.158703774031892). You may want to try with a higher value of support_fraction (current value: 0.544).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-89.884252233880460 > -160.656328588208936). You may want to try with a higher value of support_fraction (current value: 0.544).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.603187410865004 > -127.314815756935133). You may want to try with a higher value of support_fraction (current value: 0.544).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.762936706067947 > -165.775177236542021). You may want to try with a higher value of support_fraction (current value: 0.544).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.725154034598958 > -214.171762318312688). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-100.039766011953517 > -159.606482136097554). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-90.601970391088003 > -165.214573328549790). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-79.300378975429751 > -150.362017436790438). You may want to try with a higher value of support_fraction (current value: 0.540).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-76.110897414786393 > -146.364728829522704). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-75.608971157093848 > -152.135738030948630). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-76.651144457965358 > -146.046767024874214). You may want to try with a higher value of support_fraction (current value: 0.537).
2026-06-03 05:22:53,171 - cnv_pipe.cnv_pipe.batch.ess - WARNING - Not enough samples (3) compared to nearby probes (4) for probe 21259. MinCovDet requires more samples than features.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - Not enough samples (3) compared to nearby probes (4) for probe 21260. MinCovDet requires more samples than features.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - Not enough samples (3) compared to nearby probes (5) for probe 21261. MinCovDet requires more samples than features.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - Not enough samples (3) compared to nearby probes (7) for probe 21262. MinCovDet requires more samples than features.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21263 after NaN filtering. Assigning default weight of 1.0.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21264 after NaN filtering. Assigning default weight of 1.0.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21265 after NaN filtering. Assigning default weight of 1.0.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21266 after NaN filtering. Assigning default weight of 1.0.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21267 after NaN filtering. Assigning default weight of 1.0.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21268 after NaN filtering. Assigning default weight of 1.0.
2026-06-03 05:22:53,172 - cnv_pipe.cnv_pipe.batch.ess - WARNING - No valid samples remain for probe 21269 after NaN filtering. Assigning default weight of 1.0.
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-85.462402039376798 > -86.378692754932487). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-85.462402039376798 > -86.378692754932487). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.680336499061617 > -48.004216360266277). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-55.139237399664076 > -82.566016271274265). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.258357473144926 > -88.438736289634377). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.446260610461593 > -110.050360802810957). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.446260610461593 > -110.050360802810957). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-63.873526737071217 > -136.567297382142328). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-63.873526737071217 > -136.567297382142328). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-63.873526737071217 > -136.567297382142328). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-92.410583966820013 > -120.778802799743033). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-92.410583966820013 > -120.778802799743033). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-92.410583966820013 > -125.622989886201566). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-95.634478534044092 > -99.305754621967338). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-92.163275475313057 > -175.973724712073732). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-92.163275475313057 > -175.973724712073732). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-139.583399967730372 > -140.306669190383872). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-129.654750423488679 > -129.834956202201852). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.772807974988581 > -80.019115062842161). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.474975129687991 > -97.279035926723921). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.474975129687991 > -97.279035926723921). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.474975129687991 > -97.279035926723921). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.474975129687991 > -96.144989427444983). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.474975129687991 > -97.380605390819653). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.474975129687991 > -96.948096135041425). You may want to try with a higher value of support_fraction (current value: 0.527).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
2026-06-03 05:28:26,516 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Effective sample size obtained
2026-06-03 05:28:26,516 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get ploidy, all chromosomes
/opt/venv/lib/python3.12/site-packages/cnv_pipe/sca/pipeline.py:302: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/sca/pipeline.py:303: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/plotnine/ggplot.py:623: PlotnineWarning: Saving 6 x 5 in image.
/opt/venv/lib/python3.12/site-packages/plotnine/ggplot.py:624: PlotnineWarning: Filename: <_io.BufferedWriter name='A23MHW3LT4_1__sex_calls.png'>
/opt/venv/lib/python3.12/site-packages/plotnine/layer.py:374: PlotnineWarning: geom_point : Removed 6 rows containing missing values.
2026-06-03 05:29:56,168 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Ploidy obtained
2026-06-03 05:29:56,168 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get sample medians adjusting for ploidy and effective sample size
2026-06-03 05:30:01,089 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample medians obtained
2026-06-03 05:30:01,089 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Use ploidy information to get the proper masks for chrX and chrY
2026-06-03 05:30:01,089 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - 
2026-06-03 05:30:01,107 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 109866
2026-06-03 05:30:01,544 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 99235
2026-06-03 05:30:01,954 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 2644
2026-06-03 05:30:02,398 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 412
2026-06-03 05:30:02,839 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 82
2026-06-03 05:30:03,237 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 43
2026-06-03 05:30:03,613 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 17
2026-06-03 05:30:04,030 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 6
2026-06-03 05:30:04,466 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 0
2026-06-03 05:30:04,879 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 6438
2026-06-03 05:30:04,887 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 3400
2026-06-03 05:30:04,895 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 363
2026-06-03 05:30:04,901 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 47
2026-06-03 05:30:04,907 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 20
2026-06-03 05:30:04,913 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 7
2026-06-03 05:30:04,919 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 0
2026-06-03 05:30:04,926 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks for chrX and chrY obtained
2026-06-03 05:30:04,926 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get effective sample size for chrX and chrY
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.467624997657254 > -46.805663197821438). You may want to try with a higher value of support_fraction (current value: 0.512).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-46.690008723017215 > -46.698704429969965). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.027207077234259 > -59.461228702239403). You may want to try with a higher value of support_fraction (current value: 0.528).
2026-06-03 05:30:36,656 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Effective sample size for chrX and chrY obtained
2026-06-03 05:30:36,656 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get the final double norm values, adjusting for ploidies
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:239: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:239: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
2026-06-03 05:30:39,863 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Double norm values obtained
2026-06-03 05:30:39,863 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Format and write the data for sample-probe combinations
2026-06-03 05:31:39,191 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-probe data written
2026-06-03 05:31:39,191 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-level metrics. Calculating, formatting, and saving
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
2026-06-03 05:31:47,642 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-level metrics written
2026-06-03 05:31:47,642 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Save ploidy estimates
2026-06-03 05:31:47,654 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Batch pre-processing complete