mkdir -p failed for path /.config/matplotlib: [Errno 13] Permission denied: '/.config'
Matplotlib created a temporary cache directory at /tmp/matplotlib-v5laoyxl because there was an issue with the default path (/.config/matplotlib); it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
2026-06-03 04:49:24,564 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Load count data for processing
2026-06-03 04:50:27,869 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Data loaded
2026-06-03 04:50:27,891 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Find low probe mask, low sample mask, and 2D outlier mask. Autosomes only.
2026-06-03 04:50:28,151 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 3723072
2026-06-03 04:50:46,766 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 2364481
2026-06-03 04:51:06,967 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 279614
2026-06-03 04:51:26,615 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 83607
2026-06-03 04:51:47,495 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 37519
2026-06-03 04:52:08,831 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 25773
2026-06-03 04:52:29,914 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 23004
2026-06-03 04:52:50,851 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 22704
2026-06-03 04:53:12,902 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 23667
2026-06-03 04:53:35,060 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 26888
2026-06-03 04:53:57,500 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 32302
2026-06-03 04:54:19,857 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 40967
2026-06-03 04:54:42,385 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 52299
2026-06-03 04:55:04,072 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 55786
2026-06-03 04:55:25,923 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 30790
2026-06-03 04:55:46,819 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 2949
2026-06-03 04:56:14,174 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 16, outliers: 1537
2026-06-03 04:56:36,314 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 17, outliers: 325
2026-06-03 04:56:57,899 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 18, outliers: 228
2026-06-03 04:57:19,363 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 19, outliers: 185
2026-06-03 04:57:39,312 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 20, outliers: 151
2026-06-03 04:58:00,100 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 21, outliers: 123
2026-06-03 04:58:21,235 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 22, outliers: 124
2026-06-03 04:58:42,150 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 23, outliers: 123
2026-06-03 04:59:03,474 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 24, outliers: 87
2026-06-03 04:59:24,507 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks obtained
2026-06-03 04:59:24,507 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Correct counts based on melting temperature
2026-06-03 04:59:40,307 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Corrected counts obtained
2026-06-03 04:59:40,307 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Refind masks with melting-temperature corrected counts. Autosomes only.
2026-06-03 04:59:40,623 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 3723072
2026-06-03 05:00:06,995 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 2294827
2026-06-03 05:00:32,634 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 258730
2026-06-03 05:00:58,166 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 78319
2026-06-03 05:01:21,400 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 37544
2026-06-03 05:01:44,960 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 26900
2026-06-03 05:02:09,582 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 24178
2026-06-03 05:02:35,011 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 23258
2026-06-03 05:03:00,271 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 23742
2026-06-03 05:03:27,190 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 26441
2026-06-03 05:03:53,503 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 31460
2026-06-03 05:04:20,135 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 39126
2026-06-03 05:04:46,191 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 50155
2026-06-03 05:05:13,000 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 55927
2026-06-03 05:05:39,495 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 35745
2026-06-03 05:06:06,853 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 4530
2026-06-03 05:06:34,034 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 16, outliers: 652
2026-06-03 05:07:05,379 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 17, outliers: 1513
2026-06-03 05:07:31,894 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 18, outliers: 358
2026-06-03 05:07:57,934 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 19, outliers: 305
2026-06-03 05:08:25,118 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 20, outliers: 277
2026-06-03 05:08:51,123 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 21, outliers: 239
2026-06-03 05:09:16,842 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 22, outliers: 204
2026-06-03 05:09:43,064 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 23, outliers: 136
2026-06-03 05:10:08,987 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 24, outliers: 134
2026-06-03 05:10:34,704 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks obtained, from melting-temperature corrected counts
2026-06-03 05:10:34,707 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Redo melting-temperature correction with new masks
2026-06-03 05:12:43,264 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Corrected counts obtained, using second round of masks
2026-06-03 05:12:43,265 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get effective sample size per probe from covariance of nearby probes, autosomes
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.846058178081520 > -153.256684736103324). You may want to try with a higher value of support_fraction (current value: 0.540).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.872103669061673 > -149.617075206037441). You may want to try with a higher value of support_fraction (current value: 0.540).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.026379512998830 > -140.815776899812306). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-68.100276516039969 > -106.769331576765623). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.512270204648459 > -108.576360213166481). You may want to try with a higher value of support_fraction (current value: 0.540).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.478609651038894 > -143.732164392746711). You may want to try with a higher value of support_fraction (current value: 0.540).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.478609651038894 > -145.100368751822373). You may want to try with a higher value of support_fraction (current value: 0.540).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.028996533433954 > -99.520828643013431). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.991040134827387 > -99.347280454053902). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-85.297454819053527 > -114.451514341223060). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-84.930710369300513 > -114.251585303468715). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-84.930710369300513 > -114.251585303468715). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.790668214684402 > -98.332721242309631). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.779148083670293 > -97.791623106568551). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.969415553732460 > -97.539424894646984). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.790668214684402 > -98.332721242309631). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.832229984511955 > -97.026255413456582). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.946597680510976 > -93.760963469672532). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.447416705946338 > -93.455189922480869). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.035690045631810 > -93.143778197711768). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.734794257081134 > -131.277345274420128). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.629433609754578 > -126.657944614348125). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.294299785279669 > -128.956442825875001). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.661522586869296 > -136.477591257174311). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.661522586869296 > -136.477591257174311). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-59.735792421066407 > -94.715809109204756). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-59.735792421066407 > -94.715809109204756). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.547392603993238 > -131.444875025925654). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.547392603993238 > -131.444875025925654). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.226517798199367 > -105.518811275802321). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-110.101398863110944 > -110.552748354692937). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.955332179620498 > -112.924611471146648). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-108.561038879978895 > -116.383815020765567). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.493294938342572 > -116.383815020734190). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-108.561038879978895 > -116.383815020765567). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-114.830682106302504 > -118.220144736049690). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-115.089331830115896 > -115.884279064555471). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-115.089331830115896 > -115.884279064555471). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.058531525556736 > -43.775505355627963). You may want to try with a higher value of support_fraction (current value: 0.511).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.535538085160198 > -117.320429133157006). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.535538085160198 > -117.320429133157006). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.554909737509689 > -118.357798658809216). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.535538085160198 > -117.320429133157006). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.218110032335602 > -118.434947230648788). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.535538085160198 > -117.320429133157006). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.554909737509689 > -118.357798658809216). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.535538085160198 > -117.320429133157006). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.535538085160198 > -117.320429133157006). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-89.744156125181576 > -156.508758921824324). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.136188241821841 > -117.959774648686619). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.800571975100368 > -45.130549779633000). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-55.702825478398978 > -70.297981510812235). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-55.702825478398978 > -70.297981510812235). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-55.702825478398978 > -70.297981510812235). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-55.702825478398978 > -70.297981510812235). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-33.228141287064503 > -93.193433092789149). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-7.190906427323126 > -45.191599437513666). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-7.190906427323126 > -45.191599437513666). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-7.190906427323126 > -45.191599437513666). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-7.190906427323126 > -45.191599437513666). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-7.190906427323126 > -45.191599437513666). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-7.190906427323126 > -45.191599437513666). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.632668821999651 > -76.480970825914909). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.632668821999651 > -76.480970825914909). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.632668821999651 > -76.480970825914909). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-117.807258579453148 > -118.366874367777015). You may want to try with a higher value of support_fraction (current value: 0.547).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-117.807258579453148 > -118.143730816116275). You may want to try with a higher value of support_fraction (current value: 0.547).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-117.807258579453148 > -118.143730816116275). You may want to try with a higher value of support_fraction (current value: 0.547).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.783182900949484 > -142.375565888867584). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-68.718677164020107 > -97.024284179412234). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.921281469402857 > -96.729309189281039). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-68.718677164020107 > -97.024284179412234). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-68.718677164020107 > -97.024284179412234). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-68.718677164020107 > -97.024284179412234). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-68.718677164020107 > -97.024284179412234). You may want to try with a higher value of support_fraction (current value: 0.539).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.084853197749098 > -137.434681317008199). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.084853197749098 > -137.434681317008199). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.825404930036441 > -140.623320460528078). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.664693650325631 > -98.332709880571926). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-97.896867409417354 > -159.707776476687457). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-84.262731469580615 > -152.229747390903725). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-84.262731469580672 > -151.108901725544570). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-57.721012481275508 > -76.951357486812768). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-57.721012481275508 > -76.916266167226865). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-57.721012481275508 > -76.951357486812768). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-57.721012481275508 > -76.916266167226865). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.683449163108925 > -40.909530234665461). You may want to try with a higher value of support_fraction (current value: 0.514).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.742797145606204 > -74.347001648046273). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.719073387185148 > -73.672491958299815). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.742797145606204 > -74.347001648046273). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.719073387185148 > -73.672491958299815). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-19.226351877534235 > -51.271121479283408). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-18.783202058607330 > -49.143669360126260). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-19.226351877534235 > -51.676586587391583). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-19.226351877534235 > -51.271121479283408). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-18.783202058607330 > -49.143669360126260). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-19.226351877534235 > -51.676586587391583). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-19.226351877534235 > -51.271121479283408). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-18.783202058607330 > -49.143669360126260). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-19.226351877534235 > -51.676586587391583). You may want to try with a higher value of support_fraction (current value: 0.576).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.683612539185095 > -43.805930876566315). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.683612539185095 > -43.805930876566315). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.683612539185095 > -43.805930876566315). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.683612539185095 > -43.805930876566315). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-219.055756492765340 > -341.192370194997750). You may want to try with a higher value of support_fraction (current value: 0.558).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-219.055756492765340 > -341.192370194997750). You may want to try with a higher value of support_fraction (current value: 0.558).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-219.055756492765340 > -341.192370194997750). You may want to try with a higher value of support_fraction (current value: 0.558).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-219.055756492765340 > -341.192370194997750). You may want to try with a higher value of support_fraction (current value: 0.558).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-219.055756492765340 > -341.192370194997750). You may want to try with a higher value of support_fraction (current value: 0.558).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-219.055756492765340 > -341.192370194997750). You may want to try with a higher value of support_fraction (current value: 0.558).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.812876396663881 > -171.840293196401859). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.517114003240380 > -171.240234264113923). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.718382426812212 > -163.812909569721626). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.812876396663881 > -171.840293196401859). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.517114003240380 > -171.240234264113923). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.718382426812212 > -163.812909569721626). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-156.719421617077586 > -223.223276997553739). You may want to try with a higher value of support_fraction (current value: 0.551).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-224.276945860229915 > -225.643563805268968). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-224.276945860229915 > -225.643563805268968). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.364712555539228 > -167.647716797529654). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.253541285991005 > -165.338481174098149). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.364712555539228 > -167.647716797529654). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.253541285991005 > -165.338481174098149). You may want to try with a higher value of support_fraction (current value: 0.543).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-180.124628340000157 > -180.911712481266619). You may want to try with a higher value of support_fraction (current value: 0.610).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-180.124628340000157 > -180.911712481266619). You may want to try with a higher value of support_fraction (current value: 0.610).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-184.771925934062779 > -186.487774080189780). You may want to try with a higher value of support_fraction (current value: 0.610).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-184.771925934062779 > -186.487774080189780). You may want to try with a higher value of support_fraction (current value: 0.610).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.540766040910540 > -169.542907550883712). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-36.450323782619243 > -67.274152861649156). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-36.860962205935856 > -67.294732355483390). You may want to try with a higher value of support_fraction (current value: 0.523).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.001258782370932 > -107.087798198168116). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.001258782370932 > -107.087798198168116). You may want to try with a higher value of support_fraction (current value: 0.529).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.202118697115729 > -119.020430968059770). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.202118697115729 > -119.020430968059770). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.202118697115729 > -119.020430968059770). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.825115707809957 > -132.750706728657235). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.825115707809957 > -132.750706728657235). You may want to try with a higher value of support_fraction (current value: 0.536).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-104.857836267931916 > -207.241376176687595). You may want to try with a higher value of support_fraction (current value: 0.573).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-128.152642744827745 > -128.558107852935962). You may want to try with a higher value of support_fraction (current value: 0.580).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.149036184888018 > -260.403583311168859). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.013517661926102 > -258.707178454056304). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.130008903879144 > -257.481999166111166). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-134.611543099647690 > -259.196418028086555). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.643037107070910 > -199.877030624559552). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.290005999819414 > -204.419329291237943). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.643037107069830 > -203.420580173477447). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-200.395006060205333 > -243.239916344611146). You may want to try with a higher value of support_fraction (current value: 0.569).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-170.650539016471953 > -172.195481786877195). You may want to try with a higher value of support_fraction (current value: 0.623).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-169.708899747293913 > -170.015579816923548). You may want to try with a higher value of support_fraction (current value: 0.623).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-165.334283676873810 > -165.638033284240692). You may want to try with a higher value of support_fraction (current value: 0.616).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.607061040777019 > -95.988727478064305). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-111.496270100745008 > -142.652284046354453). You may want to try with a higher value of support_fraction (current value: 0.548).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.661357782292299 > -204.633528330629701). You may want to try with a higher value of support_fraction (current value: 0.549).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-73.251998810442302 > -130.465872439482496). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-70.247003328284308 > -165.531645107668226). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.056220867872346 > -47.851202298925365). You may want to try with a higher value of support_fraction (current value: 0.511).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.056220867872346 > -47.851202298925365). You may want to try with a higher value of support_fraction (current value: 0.511).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.851250355906345 > -98.704423505934514). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.442890729998737 > -96.817595823883082). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.851250355906345 > -98.704423505934514). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-67.851250355906345 > -98.700780514656003). You may want to try with a higher value of support_fraction (current value: 0.533).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.474027411250887 > -78.057416723718589). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.993267666848610 > -162.427656653456836). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-82.993267666848610 > -162.427656653456836). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-60.214938096981996 > -128.893371207792597). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-60.214938096981996 > -128.893371207792597). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-60.214938096981996 > -128.893371207792597). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-60.214938096981996 > -128.893371207792597). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-60.214938096981996 > -128.893371207792597). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.582033674741282 > -134.857931765305011). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.582033674741282 > -134.857931765305011). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.582033674741282 > -134.857931765305011). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.577289645844488 > -130.021722243746751). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.115472632941362 > -50.118462171789723). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.115472632941362 > -50.118462171789723). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.748877201153917 > -49.749990167320938). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.014495668077338 > -49.015647741939738). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.014495668077338 > -49.015071539099267). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.014495668077338 > -49.015071539099267). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.115472632941362 > -50.118462171789723). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.115472632941362 > -50.118462171789723). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.748877201153917 > -49.749990167320938). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.014495668077338 > -49.015647741939738). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.014495668077338 > -49.015071539099267). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.014495668077338 > -49.015071539099267). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.995022625247287 > -161.623086002773533). You may want to try with a higher value of support_fraction (current value: 0.542).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.150904340528356 > -77.990795661885556). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.150904340528356 > -77.990795661885556). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.150904340528356 > -77.990795661885556). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.150904340528356 > -77.990795661885556). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.150904340528356 > -77.990795661885556). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-47.150904340528356 > -77.990795661885556). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-37.240683288912223 > -93.414450932136887). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-51.415118355740638 > -102.746730627874882). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.782729715236854 > -121.029894061534748). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-81.180300106134695 > -142.345378797076137). You may want to try with a higher value of support_fraction (current value: 0.535).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.242795276174443 > -43.991341961042878). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.242795276174443 > -43.991341961042878). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.031757292734644 > -41.111331138709993). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.059279128214047 > -41.115845929513824). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.059279128214047 > -41.115845929513824). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-6.059279128214047 > -41.115845929513824). You may want to try with a higher value of support_fraction (current value: 0.510).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.684550964457856 > -121.861129190752962). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-58.907495564645615 > -191.018982402803005). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-58.907495564645615 > -191.018982402803005). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-66.147180613828141 > -160.519563598856507). You may want to try with a higher value of support_fraction (current value: 0.526).
2026-06-03 05:23:53,387 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Effective sample size obtained
2026-06-03 05:23:53,388 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get ploidy, all chromosomes
/opt/venv/lib/python3.12/site-packages/cnv_pipe/sca/pipeline.py:302: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/sca/pipeline.py:303: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/plotnine/ggplot.py:623: PlotnineWarning: Saving 6 x 5 in image.
/opt/venv/lib/python3.12/site-packages/plotnine/ggplot.py:624: PlotnineWarning: Filename: <_io.BufferedWriter name='A23NMNVLT4_1__sex_calls.png'>
/opt/venv/lib/python3.12/site-packages/plotnine/layer.py:374: PlotnineWarning: geom_point : Removed 1 rows containing missing values.
2026-06-03 05:25:13,604 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Ploidy obtained
2026-06-03 05:25:13,604 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get sample medians adjusting for ploidy and effective sample size
2026-06-03 05:25:17,811 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample medians obtained
2026-06-03 05:25:17,811 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Use ploidy information to get the proper masks for chrX and chrY
2026-06-03 05:25:17,811 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - 
2026-06-03 05:25:17,826 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 36622
2026-06-03 05:25:18,160 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 157475
2026-06-03 05:25:18,497 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 7688
2026-06-03 05:25:18,832 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 1439
2026-06-03 05:25:19,168 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 634
2026-06-03 05:25:19,502 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 338
2026-06-03 05:25:19,847 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 144
2026-06-03 05:25:20,189 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 54
2026-06-03 05:25:20,530 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 56
2026-06-03 05:25:20,868 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 7
2026-06-03 05:25:21,211 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 4
2026-06-03 05:25:21,552 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 1
2026-06-03 05:25:21,892 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 0
2026-06-03 05:25:22,238 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 2146
2026-06-03 05:25:22,247 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 4594
2026-06-03 05:25:22,254 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 813
2026-06-03 05:25:22,261 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 196
2026-06-03 05:25:22,268 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 78
2026-06-03 05:25:22,275 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 31
2026-06-03 05:25:22,282 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 12
2026-06-03 05:25:22,289 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 2
2026-06-03 05:25:22,295 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 1
2026-06-03 05:25:22,302 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 0
2026-06-03 05:25:22,310 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks for chrX and chrY obtained
2026-06-03 05:25:22,310 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get effective sample size for chrX and chrY
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.667291109310170 > -45.125911261257976). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.107501532525784 > -45.308260629569908). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-11.107501532525784 > -45.308260629569908). You may want to try with a higher value of support_fraction (current value: 0.519).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-79.069417920827476 > -80.226870709368001). You may want to try with a higher value of support_fraction (current value: 0.551).
2026-06-03 05:25:47,830 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Effective sample size for chrX and chrY obtained
2026-06-03 05:25:47,830 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get the final double norm values, adjusting for ploidies
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:239: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:239: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
2026-06-03 05:25:50,415 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Double norm values obtained
2026-06-03 05:25:50,416 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Format and write the data for sample-probe combinations
2026-06-03 05:26:39,876 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-probe data written
2026-06-03 05:26:39,876 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-level metrics. Calculating, formatting, and saving
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
2026-06-03 05:26:47,271 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-level metrics written
2026-06-03 05:26:47,271 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Save ploidy estimates
2026-06-03 05:26:47,281 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Batch pre-processing complete