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  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/75/20def5c23d5df2110f1775888c3ac5/1136_59B-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/14/b0957a2ebde71148e49b401fcb96b7/NA12878_c_0002_gDNA_0001_A23NLN3LT4_1_counts.tsv
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  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3a/3747984889aa00c28dcace0b235491/1136_4NM-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
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  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/42/a0fcbe24517853dcda4726ff7841c7/1029_J3B-N1-BDNA-1_A23NMNVLT4_1_counts.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fd/ce8417b0deedf2226c7c38355b0a39/1136_6QB-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/11/38234566927ba07eab74601eb733c0/1136_5GA-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/db/76bc324a41a8c1e2a2b255b6f0da45/1136_4S4-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e8/42a1fb34225b6dda5f7ab6439e3468/1047_IQ-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
  Downloading: s3://natera-platform-sandbox/platform_projects/altera_cnv/altera_v3_variable_regions.bed
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  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/tmp/cd/ab3dc34c234d6dc84796380231432b/germline_cnv_input.csv
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  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a8/9573086481582e214a0bdd602f6cc0/1029_YES-N1-BDNA-1_A23NLN3LT4_1_counts.tsv
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==> STAGING COMPLETE (245 inputs)

mkdir -p failed for path /.config/matplotlib: [Errno 13] Permission denied: '/.config'
Matplotlib created a temporary cache directory at /tmp/matplotlib-w544d7ha because there was an issue with the default path (/.config/matplotlib); it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
2026-06-03 04:42:02,697 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Load count data for processing
2026-06-03 04:43:22,594 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Data loaded
2026-06-03 04:43:22,602 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Find low probe mask, low sample mask, and 2D outlier mask. Autosomes only.
2026-06-03 04:43:22,972 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 4653840
2026-06-03 04:43:44,108 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 784477
2026-06-03 04:44:03,772 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 71736
2026-06-03 04:44:24,155 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 26249
2026-06-03 04:44:44,346 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 13550
2026-06-03 04:45:03,626 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 8623
2026-06-03 04:45:20,531 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 6526
2026-06-03 04:45:36,822 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 5343
2026-06-03 04:45:53,946 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 4141
2026-06-03 04:46:11,068 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 3269
2026-06-03 04:46:29,511 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 2733
2026-06-03 04:46:47,130 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 2241
2026-06-03 04:47:04,774 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 1969
2026-06-03 04:47:23,325 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 1814
2026-06-03 04:47:42,272 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 1535
2026-06-03 04:48:01,745 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 1410
2026-06-03 04:48:21,739 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 16, outliers: 1194
2026-06-03 04:48:41,416 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 17, outliers: 991
2026-06-03 04:49:00,219 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 18, outliers: 678
2026-06-03 04:49:16,385 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 19, outliers: 532
2026-06-03 04:49:31,875 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 20, outliers: 495
2026-06-03 04:49:47,452 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 21, outliers: 367
2026-06-03 04:50:02,867 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 22, outliers: 300
2026-06-03 04:50:19,364 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 23, outliers: 267
2026-06-03 04:50:36,343 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 24, outliers: 229
2026-06-03 04:50:51,739 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks obtained
2026-06-03 04:50:51,739 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Correct counts based on melting temperature
2026-06-03 04:51:05,627 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Corrected counts obtained
2026-06-03 04:51:05,628 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Refind masks with melting-temperature corrected counts. Autosomes only.
2026-06-03 04:51:05,980 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 4653840
2026-06-03 04:51:29,722 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 764480
2026-06-03 04:51:49,922 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 70484
2026-06-03 04:52:11,776 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 25606
2026-06-03 04:52:34,364 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 13311
2026-06-03 04:52:57,414 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 8642
2026-06-03 04:53:19,209 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 6307
2026-06-03 04:53:39,901 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 4758
2026-06-03 04:54:01,405 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 3784
2026-06-03 04:54:22,840 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 2973
2026-06-03 04:54:44,796 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 2318
2026-06-03 04:55:05,273 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 1923
2026-06-03 04:55:26,534 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 1579
2026-06-03 04:55:48,817 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 1367
2026-06-03 04:56:11,636 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 1201
2026-06-03 04:56:34,894 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 964
2026-06-03 04:56:57,538 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 16, outliers: 758
2026-06-03 04:57:19,085 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 17, outliers: 643
2026-06-03 04:57:40,501 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 18, outliers: 533
2026-06-03 04:58:02,287 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 19, outliers: 361
2026-06-03 04:58:23,594 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 20, outliers: 324
2026-06-03 04:58:43,816 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 21, outliers: 288
2026-06-03 04:59:04,777 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 22, outliers: 237
2026-06-03 04:59:25,270 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 23, outliers: 224
2026-06-03 04:59:47,266 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 24, outliers: 184
2026-06-03 05:00:09,593 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks obtained, from melting-temperature corrected counts
2026-06-03 05:00:09,596 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Redo melting-temperature correction with new masks
2026-06-03 05:02:43,937 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Corrected counts obtained, using second round of masks
2026-06-03 05:02:43,937 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get effective sample size per probe from covariance of nearby probes, autosomes
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.068542877137359 > -41.126723108270468). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.068542877137359 > -41.126723108270468). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.677084145877444 > -118.136304529265828). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.677084145877444 > -118.136304529265828). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.677084145877444 > -118.136304529265828). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.698482019833605 > -117.796088030654687). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.958192707678606 > -116.469318793808498). You may want to try with a higher value of support_fraction (current value: 0.531).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-83.377012457752855 > -158.418257264287121). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-83.386491851032673 > -122.165080505774654). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-83.516372852619838 > -157.684519315897120). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-109.520671585824843 > -155.888262846098144). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-71.131616274997867 > -139.530970073629476). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-83.584446158961725 > -112.908221514109101). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-83.584446158961725 > -112.215074333548728). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-78.299301005905704 > -148.927315215406878). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-60.639834876820707 > -128.272699253697795). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.012599492279051 > -92.065066205131316). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-71.986404601512177 > -135.240874441891435). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-71.986404601512177 > -135.240874441891435). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-69.372259240385972 > -132.050743831650038). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-72.248732812327958 > -106.610754911988693). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-75.323025135072598 > -146.743590273663472). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-75.323025135072598 > -146.743590273663472). You may want to try with a higher value of support_fraction (current value: 0.528).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.647846740038560 > -151.204276029212650). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.991357780596232 > -115.659777439749448). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-93.470262396814832 > -163.948306610751814). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -122.353123387640395). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -122.353123387640395). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -150.618082010015456). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -122.065441315195386). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -122.353123387640395). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -122.065441315195386). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-94.005086346317697 > -151.124961526189622). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-98.453215851698232 > -122.065441315195386). You may want to try with a higher value of support_fraction (current value: 0.534).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-64.202230061671386 > -127.137638167806742). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.667519617504695 > -120.168248782951508). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.664527181117535 > -118.629714612512913). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.667519617504695 > -120.168248782950457). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.664527181101150 > -119.312232105211223). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-88.664527181101150 > -119.312232105211223). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-86.468046239796379 > -91.157652848970372). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-62.262234340979816 > -87.505572276553920). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-109.914725228617328 > -160.033635302622429). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-143.452534177628820 > -147.007882239109563). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-140.184328375245997 > -140.199206439257807). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-130.970097142722892 > -134.317633477632455). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-152.104904930946986 > -154.171105614253719). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-152.104904930946986 > -154.171105614253719). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-152.104904930946986 > -154.171105614253719). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-9.032425082181890 > -44.281133678076287). You may want to try with a higher value of support_fraction (current value: 0.508).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-4.185355767333765 > -40.949432704749839). You may want to try with a higher value of support_fraction (current value: 0.509).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-75.309513634060579 > -138.808541317771926). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-77.399140061108923 > -170.072513554037954). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-5.627127373504969 > -40.964787884054225). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-74.865881140078855 > -167.474553441928265). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805287 > -74.500329964023067). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805280 > -74.494636868905118). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-42.530482233805287 > -74.500329964023067). You may want to try with a higher value of support_fraction (current value: 0.515).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-191.407715205818960 > -192.243774143761357). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-232.845354675906123 > -234.531008279001753). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-212.420578037108129 > -212.747303497042594). You may want to try with a higher value of support_fraction (current value: 0.541).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-271.754581706659735 > -275.284592165427739). You may want to try with a higher value of support_fraction (current value: 0.547).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.253454718793392 > -123.461266060372068). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-100.175113174721346 > -121.876894130316884). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.907092927349751 > -123.339703501200631). You may want to try with a higher value of support_fraction (current value: 0.532).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.502984868579830 > -182.236440892616258). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.385284624464731 > -181.687876712407700). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.502984868579830 > -182.236440892616258). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-122.385284624464731 > -181.687876712407700). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-165.786046340502253 > -216.965346947372382). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-160.349388717576943 > -208.147470983632900). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-162.447410438357025 > -227.516742243879349). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-165.786046340502253 > -216.965346947372382). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-160.349388717576943 > -208.147470983632900). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-162.447410438357025 > -227.516742243879349). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-165.786046340502253 > -216.965346947372382). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-160.349388717576943 > -208.147470983632900). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-162.447410438357025 > -227.516742243879349). You may want to try with a higher value of support_fraction (current value: 0.568).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-139.980246450737411 > -193.107748411262889). You may want to try with a higher value of support_fraction (current value: 0.564).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-139.980246450737411 > -193.107748411262889). You may want to try with a higher value of support_fraction (current value: 0.564).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-213.651568393484354 > -215.208065633786475). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-213.651568393484354 > -215.208065633786475). You may want to try with a higher value of support_fraction (current value: 0.530).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-146.954994792937839 > -174.016689169736367). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-145.900378150610123 > -173.133855523825162). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-146.954994792937839 > -174.016689169736367). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-145.900378150610123 > -173.133855523825162). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-153.339667986405374 > -213.282293330469486). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-153.159626204862747 > -180.371655061228068). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-153.181633042230715 > -180.382629805534918). You may want to try with a higher value of support_fraction (current value: 0.559).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.714020537007798 > -160.646216104885980). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.714020537007798 > -160.646216104885980). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-136.714020537007798 > -160.646216104885980). You may want to try with a higher value of support_fraction (current value: 0.554).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-125.957018154002441 > -221.655796815516652). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-155.635782619242036 > -193.513668403985264). You may want to try with a higher value of support_fraction (current value: 0.550).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-159.087731928990820 > -161.987894445606003). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-160.199506410765849 > -162.864527206637916). You may want to try with a higher value of support_fraction (current value: 0.537).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-43.091544390983969 > -70.118574490307012). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-41.852510260925570 > -70.147371045785121). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-52.950782229056216 > -116.315756462691695). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.036744322628230 > -116.715856107926697). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.036744322628230 > -116.715856107926697). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-52.950782229056216 > -116.315756462691695). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.036744322628230 > -116.715856107926697). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.036744322628230 > -116.715856107926697). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-52.950782229056216 > -116.315756462691695). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.036744322628230 > -116.715856107926697). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.036744322628230 > -116.715856107926697). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.139505064882684 > -130.000857986882323). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.400118505875398 > -132.395188746673909). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.139505064882684 > -130.000857986882323). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.400118505875398 > -132.395188746673909). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.139505064882684 > -130.000857986882323). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.400118505875398 > -132.395188746673909). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-53.139505064882684 > -130.000857986882323). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-56.400118505875398 > -132.395188746673909). You may want to try with a higher value of support_fraction (current value: 0.520).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-199.221405122967866 > -201.846321017830405). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-199.221405122967866 > -201.846321017830405). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-135.091534399736929 > -162.014880381600875). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-124.103155227762699 > -191.637481424693590). You may want to try with a higher value of support_fraction (current value: 0.556).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-49.160601254727979 > -109.878703320164504). You may want to try with a higher value of support_fraction (current value: 0.567).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-80.077616358373092 > -164.592689087238710). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.407092291345236 > -134.143079488345535). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-105.105625899825256 > -132.965497635324340). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.407092291345236 > -134.143079488345535). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-105.105625899825256 > -132.965497635324340). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.407092291345236 > -134.143079488345535). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-105.105625899825256 > -132.965497635324340). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.407092291345236 > -134.143079488345535). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-105.105625899825256 > -132.965497635324340). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.407092291345236 > -134.143079488345535). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-105.105625899825256 > -132.965497635324340). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-103.407092291345236 > -134.143079488345535). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-105.105625899825256 > -132.965497635324340). You may want to try with a higher value of support_fraction (current value: 0.538).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.666138992516238 > -137.306725754317540). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.666138992516238 > -137.306725754317540). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.666138992516238 > -137.306725754317540). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-101.666138992516238 > -137.306725754317540). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-10.476082916323749 > -44.044862698477758). You may want to try with a higher value of support_fraction (current value: 0.507).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-40.282466355779704 > -96.659592537092692). You may want to try with a higher value of support_fraction (current value: 0.525).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-48.439440617436652 > -170.100673267509137). You may want to try with a higher value of support_fraction (current value: 0.526).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.101659997609900 > -97.889324749196376). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.101659997609900 > -97.889324749196376). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.101659997609900 > -97.889324749196376). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-50.101659997609900 > -97.889324749196376). You may want to try with a higher value of support_fraction (current value: 0.524).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-65.205326102078374 > -93.190854374988930). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.597103547588201 > -43.970774062563336). You may want to try with a higher value of support_fraction (current value: 0.511).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-8.597103547588201 > -43.970774062563336). You may want to try with a higher value of support_fraction (current value: 0.511).
2026-06-03 05:16:45,036 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Effective sample size obtained
2026-06-03 05:16:45,036 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get ploidy, all chromosomes
/opt/venv/lib/python3.12/site-packages/cnv_pipe/sca/pipeline.py:302: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/sca/pipeline.py:303: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/plotnine/ggplot.py:623: PlotnineWarning: Saving 6 x 5 in image.
/opt/venv/lib/python3.12/site-packages/plotnine/ggplot.py:624: PlotnineWarning: Filename: <_io.BufferedWriter name='B23H2H2LT4_1__sex_calls.png'>
/opt/venv/lib/python3.12/site-packages/plotnine/layer.py:374: PlotnineWarning: geom_point : Removed 4 rows containing missing values.
2026-06-03 05:18:26,376 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Ploidy obtained
2026-06-03 05:18:26,376 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get sample medians adjusting for ploidy and effective sample size
2026-06-03 05:18:30,391 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample medians obtained
2026-06-03 05:18:30,391 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Use ploidy information to get the proper masks for chrX and chrY
2026-06-03 05:18:30,391 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - 
2026-06-03 05:18:30,413 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 73244
2026-06-03 05:18:30,815 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 79421
2026-06-03 05:18:31,236 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 4076
2026-06-03 05:18:31,653 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 1317
2026-06-03 05:18:32,076 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 551
2026-06-03 05:18:32,491 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 390
2026-06-03 05:18:32,912 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 127
2026-06-03 05:18:33,333 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 108
2026-06-03 05:18:33,758 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 8, outliers: 41
2026-06-03 05:18:34,180 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 9, outliers: 10
2026-06-03 05:18:34,608 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 10, outliers: 6
2026-06-03 05:18:35,029 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 11, outliers: 3
2026-06-03 05:18:35,450 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 12, outliers: 3
2026-06-03 05:18:35,868 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 13, outliers: 2
2026-06-03 05:18:36,287 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 14, outliers: 2
2026-06-03 05:18:36,726 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 15, outliers: 0
2026-06-03 05:18:37,159 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 0, outliers: 4292
2026-06-03 05:18:37,169 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 1, outliers: 7079
2026-06-03 05:18:37,178 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 2, outliers: 746
2026-06-03 05:18:37,186 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 3, outliers: 125
2026-06-03 05:18:37,195 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 4, outliers: 28
2026-06-03 05:18:37,203 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 5, outliers: 11
2026-06-03 05:18:37,211 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 6, outliers: 3
2026-06-03 05:18:37,219 - cnv_pipe.cnv_pipe.batch.mask - INFO - Iteration 7, outliers: 0
2026-06-03 05:18:37,228 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Masks for chrX and chrY obtained
2026-06-03 05:18:37,228 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get effective sample size for chrX and chrY
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.673836488968032 > -56.952357699431836). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.673836488968032 > -56.952357699431836). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.690409021643703 > -56.477452682789767). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.673836488968032 > -56.952357699431836). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.673836488968032 > -56.952357699431836). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.690409021643703 > -56.477452682789767). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.673836488968032 > -56.952357699431836). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.673836488968032 > -56.952357699431836). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:188: RuntimeWarning: Determinant has increased; this should not happen: log(det) > log(previous_det) (-26.690409021643703 > -56.477452682789767). You may want to try with a higher value of support_fraction (current value: 0.521).
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
/opt/venv/lib/python3.12/site-packages/sklearn/covariance/_robust_covariance.py:793: UserWarning: The covariance matrix associated to your dataset is not full rank
2026-06-03 05:19:04,453 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Effective sample size for chrX and chrY obtained
2026-06-03 05:19:04,453 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Get the final double norm values, adjusting for ploidies
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:239: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:239: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: divide by zero encountered in divide
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:249: RuntimeWarning: invalid value encountered in divide
2026-06-03 05:19:07,638 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Double norm values obtained
2026-06-03 05:19:07,638 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Format and write the data for sample-probe combinations
2026-06-03 05:20:09,034 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-probe data written
2026-06-03 05:20:09,034 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-level metrics. Calculating, formatting, and saving
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1213: RuntimeWarning: Mean of empty slice
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:316: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
/opt/venv/lib/python3.12/site-packages/numpy/lib/_nanfunctions_impl.py:1997: RuntimeWarning: Degrees of freedom <= 0 for slice.
/opt/venv/lib/python3.12/site-packages/cnv_pipe/batch/preprocess.py:318: SmallSampleWarning: One or more sample arguments is too small; all returned values will be NaN. See documentation for sample size requirements.
2026-06-03 05:20:16,360 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Sample-level metrics written
2026-06-03 05:20:16,360 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Save ploidy estimates
2026-06-03 05:20:16,371 - cnv_pipe.cnv_pipe.batch.preprocess - INFO - Batch pre-processing complete