Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/44/7a8daecbfee2a85942928672cccdfd/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f5/a9e2ccd0c8e1b97d551b9ee4f0aee5/Sig_18_tissue.md.bam.bai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/beds/altera_subpanels/hg38/FINAL_hotspot_list_07302025_hg38_sorted.bed
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/44/7a8daecbfee2a85942928672cccdfd/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f5/a9e2ccd0c8e1b97d551b9ee4f0aee5/Sig_18_tissue.md.bam
  Downloading: s3://natera-platform-sandbox/pipeline-resources/beds/altera_subpanels/hg38/foresight/xgen-exome-hyb-panel-v2_AND_altera_v3_probes_short_hg38_AND_cdx_spike_custom30off4x_hg38_AND_foresight_clarity.bed
==> STAGING COMPLETE (8 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/driver -t 31 -r Homo_sapiens_assembly38.fasta -i Sig_18_tissue.md.bam --algo HsMetricAlgo --targets_list targets/FINAL_hotspot_list_07302025_hg38_sorted.bed --baits_list baits/xgen-exome-hyb-panel-v2_AND_altera_v3_probes_short_hg38_AND_cdx_spike_custom30off4x_hg38_AND_foresight_clarity.bed Sig_18_tissue_FINAL_hotspot_list_07302025_hg38_sorted.sentieon.hs_metrics
This software is licensed to bgold@natera.com by Sentieon Inc.
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
No more license available for sentieon:Metrics
progress 5% @chr1:146000001, elapsed 420.1s, est remaining 7982.7s, peak mem 99MB, user 0.1s, sys 1.8s, output queue size 15
progress 10% @chr2:75000001, elapsed 420.2s, est remaining 3781.9s, peak mem 99MB, user 0.3s, sys 3.7s, output queue size 8
progress 15% @chr2:241000001, elapsed 420.3s, est remaining 2381.6s, peak mem 99MB, user 0.4s, sys 5.5s, output queue size 13
progress 20% @chr3:152000001, elapsed 420.3s, est remaining 1681.4s, peak mem 99MB, user 0.5s, sys 7.5s, output queue size 5
progress 25% @chr4:112000001, elapsed 420.4s, est remaining 1261.2s, peak mem 99MB, user 0.6s, sys 9.4s, output queue size 3
progress 30% @chr5:86000001, elapsed 420.5s, est remaining 981.1s, peak mem 99MB, user 0.7s, sys 11.3s, output queue size 9
progress 35% @chr6:67000001, elapsed 420.5s, est remaining 781.0s, peak mem 99MB, user 0.8s, sys 13.2s, output queue size 10
progress 40% @chr7:59000001, elapsed 420.6s, est remaining 630.9s, peak mem 99MB, user 0.9s, sys 15.2s, output queue size 15
progress 45% @chr8:61000001, elapsed 420.7s, est remaining 514.2s, peak mem 99MB, user 1.0s, sys 17.1s, output queue size 12
progress 50% @chr9:74000001, elapsed 420.7s, est remaining 420.7s, peak mem 99MB, user 1.1s, sys 19.0s, output queue size 4
progress 55% @chr10:94000001, elapsed 420.8s, est remaining 344.3s, peak mem 99MB, user 1.2s, sys 20.9s, output queue size 1
progress 60% @chr11:115000001, elapsed 420.9s, est remaining 280.6s, peak mem 99MB, user 1.3s, sys 22.8s, output queue size 8
progress 65% @chr13:15000001, elapsed 420.9s, est remaining 226.7s, peak mem 99MB, user 1.3s, sys 24.8s, output queue size 3
progress 70% @chr14:64000001, elapsed 421.0s, est remaining 180.4s, peak mem 99MB, user 1.4s, sys 26.8s, output queue size 12
progress 75% @chr16:9000001, elapsed 421.1s, est remaining 140.4s, peak mem 99MB, user 1.5s, sys 28.7s, output queue size 4
progress 80% @chr18:1, elapsed 421.1s, est remaining 105.3s, peak mem 99MB, user 1.7s, sys 30.7s, output queue size 3
progress 85% @chr20:25000001, elapsed 421.2s, est remaining 74.3s, peak mem 99MB, user 1.7s, sys 32.7s, output queue size 10
progress 90% @chrX:33000001, elapsed 421.3s, est remaining 46.8s, peak mem 129MB, user 2.4s, sys 34.0s, output queue size 114
progress 95% @chrY:26000001, elapsed 421.4s, est remaining 22.2s, peak mem 139MB, user 2.9s, sys 35.6s, output queue size 271
progress 100% @chr21:41000001, elapsed 421.7s, est remaining 0.0s, peak mem 153MB, user 3.8s, sys 37.7s, output queue size 3664
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: HsMetricAlgo
license: sentieon:Metrics=31
input file size: 50047064
reads: 1001838
contig: 3367 intervals 3217346917 bases
advance: 3219322 calls 1.424 user 18.674 sys 21.477 real
done: 1 calls 0.002 user 0.000 sys 0.003 real
exec_no_coor: 1 calls 0.000 user 0.000 sys 0.000 real
execute: 1 calls 0.001 user 0.001 sys 421.687 real
idle: 61 calls 0.002 user 0.014 sys 38.451 real
init: 1 calls 0.000 user 0.000 sys 0.000 real
overall: 160718848 mem 4.005 user 38.409 sys 422.817 real