cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/driver -t 12 -r Homo_sapiens_assembly38.fasta -i reference-NA12878-downsampled-500k.bam -i Sig_18_tissue.recalibrated.bam --interval xgen-exome-hyb-panel-v2-targets-hg38_AND_altera_v3_targets_postQC_hg38_AND_foresight_clarity_padded100bp.bed --algo TNhaplotyper2 --tumor_sample Sig_18_tissue --normal_sample reference-NA12878 --call_germline_sites --germline_vcf af-only-gnomad.hg38.vcf.gz --pon pon_tnseq_42_curated_v4.vcf.gz positive_somatic_control_2.tnseq.vcf.gz --algo OrientationBias --tumor_sample Sig_18_tissue positive_somatic_control_2.tnseq.orientation_data.tsv --algo ContaminationModel --tumor_sample Sig_18_tissue --normal_sample reference-NA12878 --vcf af-only-gnomad.hg38.vcf.gz --tumor_segments positive_somatic_control_2.tnseq.segments positive_somatic_control_2.tnseq.contamination_data.tsv
This software is licensed to bgold@natera.com by Sentieon Inc.
progress 5% @chr1:113698162, elapsed 0.7s, est remaining 12.8s, peak mem 145MB, user 6.8s, sys 0.5s, output queue size 4
progress 10% @chr2:3603546, elapsed 1.3s, est remaining 11.6s, peak mem 145MB, user 13.1s, sys 0.9s, output queue size 6
progress 15% @chr2:178529860, elapsed 1.9s, est remaining 11.0s, peak mem 146MB, user 20.0s, sys 1.3s, output queue size 22
progress 20% @chr3:57483276, elapsed 2.6s, est remaining 10.2s, peak mem 147MB, user 26.3s, sys 1.6s, output queue size 0
progress 25% @chr4:70631570, elapsed 3.2s, est remaining 9.7s, peak mem 148MB, user 33.3s, sys 2.0s, output queue size 1
progress 30% @chr5:135873921, elapsed 3.9s, est remaining 9.1s, peak mem 150MB, user 40.1s, sys 2.4s, output queue size 4
progress 35% @chr6:104957999, elapsed 4.5s, est remaining 8.3s, peak mem 151MB, user 46.2s, sys 2.8s, output queue size 3
progress 40% @chr7:106284249, elapsed 5.2s, est remaining 7.7s, peak mem 152MB, user 52.9s, sys 3.2s, output queue size 7
progress 45% @chr8:143835562, elapsed 5.8s, est remaining 7.1s, peak mem 153MB, user 59.8s, sys 3.6s, output queue size 0
progress 50% @chr10:21726144, elapsed 6.5s, est remaining 6.5s, peak mem 154MB, user 66.2s, sys 4.1s, output queue size 1
progress 55% @chr11:34132926, elapsed 7.1s, est remaining 5.8s, peak mem 154MB, user 72.4s, sys 4.5s, output queue size 6
progress 60% @chr12:12718707, elapsed 7.7s, est remaining 5.1s, peak mem 155MB, user 78.9s, sys 4.9s, output queue size 10
progress 65% @chr13:32078734, elapsed 8.4s, est remaining 4.5s, peak mem 155MB, user 85.6s, sys 5.2s, output queue size 10
progress 70% @chr15:35521993, elapsed 9.0s, est remaining 3.9s, peak mem 155MB, user 92.2s, sys 5.6s, output queue size 0
progress 75% @chr16:28494582, elapsed 9.6s, est remaining 3.2s, peak mem 156MB, user 98.6s, sys 6.0s, output queue size 0
progress 80% @chr17:40034816, elapsed 10.3s, est remaining 2.6s, peak mem 156MB, user 105.7s, sys 6.4s, output queue size 2
progress 85% @chr19:1805788, elapsed 11.0s, est remaining 1.9s, peak mem 157MB, user 112.5s, sys 6.8s, output queue size 2
progress 90% @chr19:54632916, elapsed 11.6s, est remaining 1.3s, peak mem 158MB, user 119.1s, sys 7.2s, output queue size 0
progress 95% @chr22:31897382, elapsed 13.3s, est remaining 0.7s, peak mem 357MB, user 135.4s, sys 7.7s, output queue size 10
progress 100% @chrY:24840631, elapsed 13.9s, est remaining 0.0s, peak mem 357MB, user 141.4s, sys 8.2s, output queue size 409
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000606a6
  features: 1f8bfbff fffa320b
  extended: f1bf07ab 00407f5a
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8375C CPU @ 2.90GHz
threads: 12 max 64
algo: TNhaplotyper2 OrientationBias ContaminationModel
license: sentieon:TNhaplotyper=12
input file size: 71721858 93248820
output file size: 53230
reads: 1502521
contig: 178193 intervals 76355618 bases
"assemble": 221 calls 0.483 user 0.011 sys 0.499 real
"assemble_addRead": 221 calls 0.000 user 0.000 sys 0.008 real
"assemble_buildGraph": 496 calls 0.178 user 0.010 sys 0.215 real
"assemble_computecigar": 329 calls 0.041 user 0.000 sys 0.077 real
"assemble_kg_build_calcsize": 496 calls 0.086 user 0.000 sys 0.103 real
"assemble_kg_build_clear": 650 calls 0.010 user 0.000 sys 0.008 real
"assemble_kg_build_prepare": 992 calls 0.079 user 0.001 sys 0.096 real
"assemble_kg_build_threading": 342 calls 0.092 user 0.010 sys 0.108 real
"assemble_kg_op1": 342 calls 0.125 user 0.000 sys 0.078 real
"assemble_kg_op2": 342 calls 0.010 user 0.000 sys 0.005 real
"assemble_kg_op3": 342 calls 0.010 user 0.000 sys 0.006 real
"assemble_sg_clean": 329 calls 0.010 user 0.000 sys 0.025 real
"assemble_sg_create": 329 calls 0.060 user 0.000 sys 0.039 real
"checkGraph": 221 calls 0.000 user 0.000 sys 0.001 real
"findHaplotype": 221 calls 0.051 user 0.000 sys 0.081 real
advance: 189104 calls 15.387 user 0.348 sys 18.806 real
assemble_region: 221 calls 0.534 user 0.011 sys 0.590 real
build_pileup: 70986 calls 0.454 user 0.000 sys 0.455 real
build_stats: 71711 calls 1.822 user 0.041 sys 2.281 real
build_variants: 178 calls 0.000 user 0.000 sys 0.001 real
calc: 128717 calls 2.320 user 0.047 sys 2.916 real
calc_region: 178 calls 2.868 user 0.020 sys 2.977 real
call_region: 178 calls 0.033 user 0.000 sys 0.059 real
clip_region: 399 calls 0.070 user 0.000 sys 0.044 real
done: 1 calls 0.468 user 0.000 sys 0.471 real
execute: 1 calls 0.008 user 0.002 sys 13.886 real
fetch: 743546 calls 0.755 user 0.098 sys 0.891 real
fetch_ref: 745726 calls 1.685 user 0.382 sys 2.701 real
fetch_region: 221 calls 0.011 user 0.000 sys 0.009 real
fetch_vcf: 189104 calls 41.945 user 0.800 sys 55.666 real
idle: 35 calls 0.008 user 0.002 sys 12.830 real
init: 1 calls 0.050 user 0.000 sys 0.058 real
pairhmm: 837 calls 4.607 user 0.008 sys 4.761 real
realign: 178 calls 0.574 user 0.000 sys 0.619 real
region: 367297 calls 3.440 user 0.118 sys 3.677 real
tracker: 367297 calls 0.416 user 0.055 sys 0.543 real
trim_region: 221 calls 0.000 user 0.000 sys 0.002 real
overall: 374927360 mem 157.372 user 11.088 sys 15.179 real