Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/59/4eb74d08abd9c45ff9e7adefa58af6/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/beds/altera_subpanels/hg38/FINAL_hotspot_list_07302025_hg38_sorted.bed
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/59/4eb74d08abd9c45ff9e7adefa58af6/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a2/4c4bfe29eae3280a45e31a9fd363bf/Sig_18_Blood.md.bam
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a2/4c4bfe29eae3280a45e31a9fd363bf/Sig_18_Blood.md.bam.bai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/beds/altera_subpanels/hg38/foresight/xgen-exome-hyb-panel-v2_AND_altera_v3_probes_short_hg38_AND_cdx_spike_custom30off4x_hg38_AND_foresight_clarity.bed
==> STAGING COMPLETE (8 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/driver -t 31 -r Homo_sapiens_assembly38.fasta -i Sig_18_Blood.md.bam --algo HsMetricAlgo --targets_list targets/FINAL_hotspot_list_07302025_hg38_sorted.bed --baits_list baits/xgen-exome-hyb-panel-v2_AND_altera_v3_probes_short_hg38_AND_cdx_spike_custom30off4x_hg38_AND_foresight_clarity.bed Sig_18_Blood_FINAL_hotspot_list_07302025_hg38_sorted.sentieon.hs_metrics
This software is licensed to bgold@natera.com by Sentieon Inc.
progress 5% @chr1:159000001, elapsed 0.0s, est remaining 0.6s, peak mem 99MB, user 0.0s, sys 0.6s, output queue size 17
progress 10% @chr2:79000001, elapsed 0.1s, est remaining 0.5s, peak mem 99MB, user 0.1s, sys 1.2s, output queue size 7
progress 15% @chr2:224000001, elapsed 0.1s, est remaining 0.5s, peak mem 99MB, user 0.3s, sys 1.9s, output queue size 20
progress 20% @chr3:153000001, elapsed 0.1s, est remaining 0.4s, peak mem 99MB, user 0.5s, sys 2.5s, output queue size 18
progress 25% @chr4:123000001, elapsed 0.1s, est remaining 0.4s, peak mem 99MB, user 0.7s, sys 3.1s, output queue size 12
progress 30% @chr5:92000001, elapsed 0.2s, est remaining 0.4s, peak mem 99MB, user 0.8s, sys 3.9s, output queue size 13
progress 35% @chr6:67000001, elapsed 0.2s, est remaining 0.4s, peak mem 99MB, user 0.9s, sys 4.6s, output queue size 9
progress 40% @chr7:62000001, elapsed 0.2s, est remaining 0.3s, peak mem 99MB, user 1.0s, sys 5.2s, output queue size 18
progress 45% @chr8:65000001, elapsed 0.2s, est remaining 0.3s, peak mem 99MB, user 1.1s, sys 6.0s, output queue size 15
progress 50% @chr9:74000001, elapsed 0.3s, est remaining 0.3s, peak mem 99MB, user 1.3s, sys 6.6s, output queue size 16
progress 55% @chr10:101000001, elapsed 0.3s, est remaining 0.2s, peak mem 99MB, user 1.5s, sys 7.1s, output queue size 14
progress 60% @chr11:127000001, elapsed 0.3s, est remaining 0.2s, peak mem 99MB, user 1.7s, sys 7.8s, output queue size 15
progress 65% @chr13:19000001, elapsed 0.4s, est remaining 0.2s, peak mem 99MB, user 1.8s, sys 8.6s, output queue size 8
progress 70% @chr14:67000001, elapsed 0.4s, est remaining 0.2s, peak mem 99MB, user 1.9s, sys 9.3s, output queue size 16
progress 75% @chr16:18000001, elapsed 0.4s, est remaining 0.1s, peak mem 99MB, user 2.0s, sys 10.0s, output queue size 17
progress 80% @chr17:65000001, elapsed 0.4s, est remaining 0.1s, peak mem 99MB, user 2.1s, sys 10.7s, output queue size 19
progress 85% @chr20:5000001, elapsed 0.5s, est remaining 0.1s, peak mem 99MB, user 2.3s, sys 11.4s, output queue size 19
progress 90% @chrX:30000001, elapsed 0.5s, est remaining 0.1s, peak mem 120MB, user 2.8s, sys 11.9s, output queue size 114
progress 95% @chrY:38000001, elapsed 0.6s, est remaining 0.0s, peak mem 132MB, user 3.3s, sys 12.4s, output queue size 276
progress 100% @chr21:41000001, elapsed 0.9s, est remaining 0.0s, peak mem 153MB, user 4.5s, sys 13.3s, output queue size 3664
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: HsMetricAlgo
license: sentieon:Metrics=31
input file size: 52290597
reads: 1001133
contig: 3367 intervals 3217346917 bases
advance: 3219322 calls 1.471 user 6.945 sys 8.587 real
done: 1 calls 0.000 user 0.000 sys 0.001 real
exec_no_coor: 1 calls 0.000 user 0.000 sys 0.000 real
execute: 1 calls 0.003 user 0.001 sys 0.865 real
idle: 79 calls 0.005 user 0.011 sys 39.005 real
init: 1 calls 0.000 user 0.000 sys 0.000 real
overall: 160538624 mem 4.744 user 13.922 sys 1.998 real