This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_81F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2539.910 CPU sec, 89.576 real sec
[M::process] read 773898 sequences (100000129 bp) in 1.142 CPU sec, 1.145 real sec...
[M::process] read 772590 sequences (100000170 bp) in 1.873 CPU sec, 1.970 real sec...
[M::process] read 772372 sequences (100000141 bp) in 1.845 CPU sec, 1.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296007, 37, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 249, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (413.96, 354.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.21, 64.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 1097, 3232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9316)
[M::mem_pestat] mean and std.dev: (1908.27, 2259.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 663, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (570.04, 490.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770848 sequences (100000087 bp) in 1.715 CPU sec, 1.721 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296117, 43, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 381, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1879)
[M::mem_pestat] mean and std.dev: (445.44, 335.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (158.09, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 642, 1953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4843)
[M::mem_pestat] mean and std.dev: (953.73, 690.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 344, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (428.19, 351.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295687, 40, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 372, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (457.41, 360.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.61, 65.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 521, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2978)
[M::mem_pestat] mean and std.dev: (674.00, 627.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 329, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (664.89, 773.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773898 reads in 412.808 CPU sec, 13.372 real sec
[M::mem_process_seqs] Processed 772590 reads in 283.349 CPU sec, 9.287 real sec
[M::mem_process_seqs] Processed 772372 reads in 316.688 CPU sec, 10.384 real sec
sorting block 0, #reads = 1085969 mem = 536879972 peak = 581664768
[M::process] read 770526 sequences (100000141 bp) in 2.445 CPU sec, 2.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 295905, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 322, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3013)
[M::mem_pestat] mean and std.dev: (725.62, 780.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.51, 65.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 662, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3803)
[M::mem_pestat] mean and std.dev: (904.97, 868.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 815, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3372)
[M::mem_pestat] mean and std.dev: (778.08, 576.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 1, #reads = 1087198 mem = 536883202 peak = 805011456
[M::process] read 769724 sequences (100000100 bp) in 2.892 CPU sec, 3.109 real sec...
[M::process] read 770200 sequences (100000010 bp) in 1.847 CPU sec, 1.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295180, 46, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 369, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3746)
[M::mem_pestat] mean and std.dev: (646.63, 727.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4930)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.64, 65.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 536, 4114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11710)
[M::mem_pestat] mean and std.dev: (2608.37, 3528.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 440, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (712.72, 666.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770848 reads in 258.335 CPU sec, 8.261 real sec
[M::mem_process_seqs] Processed 770526 reads in 178.444 CPU sec, 5.729 real sec
sorting block 2, #reads = 1086376 mem = 536880326 peak = 805011456
[M::process] read 770346 sequences (100000118 bp) in 2.691 CPU sec, 2.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295390, 42, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 279, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488)
[M::mem_pestat] mean and std.dev: (537.17, 496.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4601)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.37, 66.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 722, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3877)
[M::mem_pestat] mean and std.dev: (755.32, 872.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 399, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (518.16, 396.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772006 sequences (100000041 bp) in 1.955 CPU sec, 1.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295164, 24, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 370, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (551.58, 571.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.26, 66.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 786, 1449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4011)
[M::mem_pestat] mean and std.dev: (1081.08, 1182.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 260, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (495.51, 554.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295666, 45, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 447, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (486.65, 453.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.80, 66.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 585, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4527)
[M::mem_pestat] mean and std.dev: (1005.53, 957.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 251, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (493.06, 537.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769724 reads in 367.475 CPU sec, 11.798 real sec
[M::mem_process_seqs] Processed 770200 reads in 288.664 CPU sec, 9.346 real sec
sorting block 3, #reads = 1085250 mem = 536878632 peak = 841609216
[M::mem_process_seqs] Processed 770346 reads in 331.343 CPU sec, 10.833 real sec
[M::process] read 771760 sequences (100000038 bp) in 2.712 CPU sec, 3.009 real sec...
sorting block 4, #reads = 1085768 mem = 536878501 peak = 841609216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295439, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 277, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (345.76, 261.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.84, 65.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 605, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3545)
[M::mem_pestat] mean and std.dev: (725.60, 609.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 250, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (266.80, 152.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770488 sequences (100000091 bp) in 2.713 CPU sec, 2.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295833, 39, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 324, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (454.96, 404.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.87, 65.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 574, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3557)
[M::mem_pestat] mean and std.dev: (884.81, 965.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 418, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (534.44, 480.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772006 reads in 270.103 CPU sec, 8.770 real sec
[M::process] read 770118 sequences (100000211 bp) in 2.037 CPU sec, 2.191 real sec...
sorting block 5, #reads = 1086020 mem = 536879899 peak = 841609216
[M::mem_process_seqs] Processed 771760 reads in 188.193 CPU sec, 6.058 real sec
[M::process] read 770488 sequences (100000108 bp) in 2.778 CPU sec, 3.020 real sec...
sorting block 6, #reads = 1085646 mem = 536886976 peak = 841609216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295468, 24, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 298, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (430.49, 443.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.28, 65.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 393, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (312.65, 328.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 334, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (461.63, 403.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770488 reads in 154.316 CPU sec, 5.058 real sec
[M::process] read 768894 sequences (100000216 bp) in 2.765 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295499, 33, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 331, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (480.88, 487.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.81, 66.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 950, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3397)
[M::mem_pestat] mean and std.dev: (807.29, 490.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 300, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (419.10, 365.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768282 sequences (100000059 bp) in 2.525 CPU sec, 2.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 295014, 34, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 295, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (420.10, 364.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.80, 66.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 454, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5158)
[M::mem_pestat] mean and std.dev: (729.35, 929.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 304, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454)
[M::mem_pestat] mean and std.dev: (445.32, 452.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 294175, 40, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 215, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (348.98, 360.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.48, 66.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 582, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4385)
[M::mem_pestat] mean and std.dev: (820.34, 898.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 435, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (706.50, 720.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770118 reads in 416.255 CPU sec, 13.464 real sec
sorting block 7, #reads = 1085313 mem = 536881834 peak = 841609216
[M::mem_process_seqs] Processed 770488 reads in 298.186 CPU sec, 9.657 real sec
[M::mem_process_seqs] Processed 768894 reads in 331.788 CPU sec, 10.808 real sec
sorting block 8, #reads = 1085656 mem = 536887791 peak = 853991424
[M::process] read 771730 sequences (100000020 bp) in 2.966 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 294314, 36, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 298, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (416.46, 338.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.10, 66.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 199, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2436)
[M::mem_pestat] mean and std.dev: (466.20, 546.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 309, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (389.91, 258.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767834 sequences (100000155 bp) in 3.091 CPU sec, 3.360 real sec...
sorting block 9, #reads = 1083287 mem = 536883938 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 294379, 45, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 276, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (284.55, 204.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.13, 65.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 619, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (579.05, 568.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 278, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (361.36, 295.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767634 sequences (100000047 bp) in 2.349 CPU sec, 2.392 real sec...
[M::mem_process_seqs] Processed 768282 reads in 287.679 CPU sec, 9.244 real sec
[M::mem_process_seqs] Processed 771730 reads in 210.619 CPU sec, 6.736 real sec
sorting block 10, #reads = 1081008 mem = 536884774 peak = 853991424
[M::process] read 767388 sequences (100000297 bp) in 2.932 CPU sec, 3.285 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294023, 37, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (332.31, 253.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.41, 67.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 871, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4752)
[M::mem_pestat] mean and std.dev: (1128.49, 1301.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (406.40, 353.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767156 sequences (100000262 bp) in 1.995 CPU sec, 2.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 293360, 60, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 343, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (641.56, 740.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.19, 66.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3943)
[M::mem_pestat] mean and std.dev: (758.12, 867.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5196)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 281, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (416.55, 437.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767834 reads in 282.894 CPU sec, 9.433 real sec
[M::mem_process_seqs] Processed 767634 reads in 185.629 CPU sec, 5.999 real sec
sorting block 11, #reads = 1076204 mem = 536877787 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293758, 40, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 250, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2340)
[M::mem_pestat] mean and std.dev: (464.56, 540.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.37, 66.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 637, 2102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5556)
[M::mem_pestat] mean and std.dev: (1356.85, 1481.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 327, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (463.35, 427.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766670 sequences (100000136 bp) in 2.999 CPU sec, 3.266 real sec...
[M::process] read 766156 sequences (100000246 bp) in 2.270 CPU sec, 2.277 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293672, 37, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 299, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (544.82, 579.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.37, 66.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 1038, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5009)
[M::mem_pestat] mean and std.dev: (1187.27, 1009.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 399, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (574.59, 492.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767388 reads in 266.084 CPU sec, 8.537 real sec
sorting block 12, #reads = 1080762 mem = 536882259 peak = 853991424
[M::mem_process_seqs] Processed 767156 reads in 186.182 CPU sec, 5.980 real sec
sorting block 13, #reads = 1081848 mem = 536879364 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 293117, 44, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 399, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101)
[M::mem_pestat] mean and std.dev: (593.62, 587.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.97, 67.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 471, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2903)
[M::mem_pestat] mean and std.dev: (701.98, 729.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 209, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (328.06, 301.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766316 sequences (100000049 bp) in 3.329 CPU sec, 3.631 real sec...
[M::process] read 766204 sequences (100000062 bp) in 2.196 CPU sec, 2.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 293392, 38, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 261, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (321.60, 263.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.20, 67.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 539, 2146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6008)
[M::mem_pestat] mean and std.dev: (888.31, 1069.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 390, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (399.91, 283.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766670 reads in 267.599 CPU sec, 8.591 real sec
[M::mem_process_seqs] Processed 766156 reads in 188.946 CPU sec, 6.071 real sec
sorting block 14, #reads = 1080400 mem = 536878258 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 292685, 37, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 260, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1633)
[M::mem_pestat] mean and std.dev: (381.42, 348.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.14, 67.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 429, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (514.29, 392.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 666, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4499)
[M::mem_pestat] mean and std.dev: (1062.52, 1223.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771224 sequences (100000094 bp) in 3.500 CPU sec, 3.854 real sec...
[M::process] read 771908 sequences (100000073 bp) in 2.210 CPU sec, 2.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293106, 49, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 290, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2687)
[M::mem_pestat] mean and std.dev: (559.16, 563.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (162.54, 67.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 483)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 687, 2874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8180)
[M::mem_pestat] mean and std.dev: (1540.35, 1760.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 319, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (523.54, 474.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766316 reads in 267.956 CPU sec, 8.617 real sec
sorting block 15, #reads = 1080322 mem = 536880704 peak = 853991424
[M::mem_process_seqs] Processed 766204 reads in 183.361 CPU sec, 5.902 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295389, 37, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 262, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (409.54, 360.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.02, 65.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 955, 4339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12401)
[M::mem_pestat] mean and std.dev: (2474.51, 2714.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (568.98, 562.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1080300 mem = 536882117 peak = 853991424
[M::process] read 770524 sequences (100000036 bp) in 3.461 CPU sec, 3.854 real sec...
[M::process] read 770418 sequences (100000255 bp) in 1.977 CPU sec, 1.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295892, 36, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 338, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (521.96, 485.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.75, 65.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 315, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452)
[M::mem_pestat] mean and std.dev: (459.38, 549.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 376, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (560.18, 559.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771224 reads in 266.388 CPU sec, 8.576 real sec
[M::mem_process_seqs] Processed 771908 reads in 181.559 CPU sec, 5.867 real sec
sorting block 17, #reads = 1082031 mem = 536877671 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 295106, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 307, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (388.84, 382.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.69, 66.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 691, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4823)
[M::mem_pestat] mean and std.dev: (976.27, 962.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 269, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (301.06, 212.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770734 sequences (100000091 bp) in 3.511 CPU sec, 3.793 real sec...
[M::process] read 770040 sequences (100000191 bp) in 2.186 CPU sec, 2.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295307, 23, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 396, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (380.14, 309.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2342)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.56, 65.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 347, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (460.76, 386.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 340, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (529.34, 462.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770524 reads in 260.747 CPU sec, 8.349 real sec
sorting block 18, #reads = 1087054 mem = 536879109 peak = 853991424
[M::mem_process_seqs] Processed 770418 reads in 179.635 CPU sec, 5.763 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295403, 36, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 329, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (459.36, 401.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.57, 65.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 719, 2750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7654)
[M::mem_pestat] mean and std.dev: (1349.72, 1458.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 530, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (650.28, 553.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1085290 mem = 536881320 peak = 853991424
[M::process] read 769324 sequences (100000010 bp) in 3.395 CPU sec, 3.854 real sec...
[M::process] read 769602 sequences (100000162 bp) in 2.070 CPU sec, 2.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295700, 41, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 270, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2208)
[M::mem_pestat] mean and std.dev: (347.65, 346.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.75, 66.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 621, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (843.44, 693.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 273, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (569.33, 690.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770734 reads in 262.023 CPU sec, 8.428 real sec
[M::mem_process_seqs] Processed 770040 reads in 179.697 CPU sec, 5.782 real sec
sorting block 20, #reads = 1086564 mem = 536881366 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295264, 52, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 340, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (444.73, 435.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.34, 66.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 500, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (623.57, 580.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 327, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (520.09, 463.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770324 sequences (100000193 bp) in 3.260 CPU sec, 3.540 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295114, 31, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 297, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (576.65, 648.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.49, 66.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 563, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4222)
[M::mem_pestat] mean and std.dev: (817.74, 904.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 325, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (378.13, 332.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770592 sequences (100000078 bp) in 2.525 CPU sec, 2.936 real sec...
[M::mem_process_seqs] Processed 769324 reads in 257.927 CPU sec, 8.434 real sec
sorting block 21, #reads = 1086005 mem = 536878905 peak = 853991424
[M::mem_process_seqs] Processed 769602 reads in 180.456 CPU sec, 5.935 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 295542, 48, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 485, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (640.34, 557.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.94, 66.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 509, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4032)
[M::mem_pestat] mean and std.dev: (827.64, 959.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 276, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (460.91, 448.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770166 sequences (100000276 bp) in 3.087 CPU sec, 3.344 real sec...
sorting block 22, #reads = 1086272 mem = 536879200 peak = 853991424
[M::process] read 769232 sequences (100000071 bp) in 2.055 CPU sec, 2.060 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 295723, 58, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 262, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2676)
[M::mem_pestat] mean and std.dev: (461.84, 507.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.70, 65.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 457, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2687)
[M::mem_pestat] mean and std.dev: (597.51, 566.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 314, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (296.73, 154.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770324 reads in 262.004 CPU sec, 8.638 real sec
[M::mem_process_seqs] Processed 770592 reads in 182.936 CPU sec, 6.049 real sec
sorting block 23, #reads = 1087103 mem = 536881443 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 294782, 30, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 432, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (665.11, 687.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.33, 66.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 592, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (545.38, 387.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 294, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (516.60, 555.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769140 sequences (100000156 bp) in 3.138 CPU sec, 3.483 real sec...
[M::process] read 768458 sequences (100000194 bp) in 2.400 CPU sec, 2.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 295221, 44, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 305, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (523.98, 526.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.25, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 778, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (682.38, 546.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 336, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (572.84, 627.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770166 reads in 259.314 CPU sec, 8.493 real sec
[M::mem_process_seqs] Processed 769232 reads in 182.027 CPU sec, 6.002 real sec
sorting block 24, #reads = 1085788 mem = 536883258 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294512, 37, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 272, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (296.90, 198.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (160.09, 65.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 777, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (764.45, 483.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 322, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (377.24, 254.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768812 sequences (100000089 bp) in 3.486 CPU sec, 3.939 real sec...
[M::process] read 769690 sequences (100000128 bp) in 2.057 CPU sec, 2.074 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293693, 49, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 358, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (498.20, 484.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.52, 66.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 575, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5259)
[M::mem_pestat] mean and std.dev: (935.38, 991.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 313, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (386.57, 299.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769140 reads in 263.547 CPU sec, 8.567 real sec
sorting block 25, #reads = 1085053 mem = 536882530 peak = 853991424
[M::mem_process_seqs] Processed 768458 reads in 183.284 CPU sec, 5.974 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294052, 42, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 304, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2944)
[M::mem_pestat] mean and std.dev: (563.87, 589.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.90, 65.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 876, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289)
[M::mem_pestat] mean and std.dev: (690.42, 576.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 420, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (666.51, 629.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1082724 mem = 536885354 peak = 853991424
[M::process] read 770658 sequences (100000122 bp) in 3.453 CPU sec, 3.875 real sec...
[M::process] read 768242 sequences (100000195 bp) in 2.332 CPU sec, 2.388 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293868, 39, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 309, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (505.65, 512.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.70, 65.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 455, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2891)
[M::mem_pestat] mean and std.dev: (570.50, 622.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 361, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (503.47, 438.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768812 reads in 269.157 CPU sec, 8.785 real sec
[M::mem_process_seqs] Processed 769690 reads in 189.301 CPU sec, 6.154 real sec
sorting block 27, #reads = 1083061 mem = 536889815 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294179, 32, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 286, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (505.56, 527.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.93, 65.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 687, 3230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9264)
[M::mem_pestat] mean and std.dev: (2062.94, 2864.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 382, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (525.34, 528.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768352 sequences (100000009 bp) in 3.287 CPU sec, 3.502 real sec...
[M::process] read 767840 sequences (100000036 bp) in 2.055 CPU sec, 2.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 293965, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 264, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (281.40, 213.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.72, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 601, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3461)
[M::mem_pestat] mean and std.dev: (832.92, 804.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 434, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4566)
[M::mem_pestat] mean and std.dev: (859.36, 988.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6031)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770658 reads in 277.577 CPU sec, 8.979 real sec
sorting block 28, #reads = 1076763 mem = 536877246 peak = 853991424
[M::mem_process_seqs] Processed 768242 reads in 186.733 CPU sec, 6.052 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 293638, 43, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 339, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (505.09, 551.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.09, 66.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 507, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (469.28, 519.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 354, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (493.77, 370.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1081164 mem = 536884432 peak = 853991424
[M::process] read 767478 sequences (100000155 bp) in 3.404 CPU sec, 3.620 real sec...
[M::process] read 766746 sequences (100000181 bp) in 2.315 CPU sec, 2.344 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 293491, 34, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 238, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (507.03, 560.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.15, 66.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 408, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (614.38, 688.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 286, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (368.53, 262.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768352 reads in 264.302 CPU sec, 8.532 real sec
[M::mem_process_seqs] Processed 767840 reads in 181.169 CPU sec, 5.842 real sec
sorting block 30, #reads = 1080425 mem = 536883201 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 293824, 42, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 500, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (597.60, 575.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.84, 67.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 460, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (650.03, 787.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 409, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3437)
[M::mem_pestat] mean and std.dev: (739.06, 821.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766866 sequences (100000144 bp) in 3.163 CPU sec, 3.563 real sec...
[M::process] read 766598 sequences (100000228 bp) in 2.097 CPU sec, 2.101 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 293258, 36, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 308, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (360.37, 283.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.14, 67.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 676, 2345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6315)
[M::mem_pestat] mean and std.dev: (1161.21, 1270.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 193, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (313.53, 288.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767478 reads in 265.005 CPU sec, 8.580 real sec
sorting block 31, #reads = 1082400 mem = 536883089 peak = 853991424
[M::mem_process_seqs] Processed 766746 reads in 184.825 CPU sec, 5.992 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 293043, 43, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 224, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3664)
[M::mem_pestat] mean and std.dev: (606.78, 749.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.02, 67.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 582, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3360)
[M::mem_pestat] mean and std.dev: (739.25, 684.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 245, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (409.52, 376.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772352 sequences (100000294 bp) in 3.105 CPU sec, 3.356 real sec...
sorting block 32, #reads = 1081132 mem = 536879225 peak = 853991424
[M::process] read 772382 sequences (100000001 bp) in 2.434 CPU sec, 2.553 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293464, 25, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1475)
[M::mem_pestat] mean and std.dev: (289.95, 281.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.99, 67.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 782, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3813)
[M::mem_pestat] mean and std.dev: (931.75, 827.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 447, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (554.54, 479.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766866 reads in 265.276 CPU sec, 8.577 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 294926, 49, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 403, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (539.23, 517.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.24, 64.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 1081, 5084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14730)
[M::mem_pestat] mean and std.dev: (2801.45, 3362.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 348, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2593)
[M::mem_pestat] mean and std.dev: (513.78, 460.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771116 sequences (100000123 bp) in 2.808 CPU sec, 2.985 real sec...
[M::mem_process_seqs] Processed 772352 reads in 158.451 CPU sec, 5.365 real sec
sorting block 33, #reads = 1080523 mem = 536889691 peak = 853991424
[M::mem_process_seqs] Processed 766598 reads in 395.867 CPU sec, 13.081 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295663, 32, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 356, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (480.80, 423.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.26, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 534, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3676)
[M::mem_pestat] mean and std.dev: (683.23, 668.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 344, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (548.96, 554.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1082633 mem = 536879067 peak = 853991424
[M::process] read 770214 sequences (100000204 bp) in 3.294 CPU sec, 3.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295218, 34, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (266.70, 193.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.19, 65.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 762, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4304)
[M::mem_pestat] mean and std.dev: (807.17, 597.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5638)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 642, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (498.75, 376.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769636 sequences (100000039 bp) in 2.011 CPU sec, 2.034 real sec...
[M::mem_process_seqs] Processed 772382 reads in 299.060 CPU sec, 9.678 real sec
[M::mem_process_seqs] Processed 771116 reads in 183.515 CPU sec, 5.951 real sec
sorting block 35, #reads = 1083240 mem = 536879998 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295351, 27, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 258, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (287.71, 202.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.04, 66.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 814, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3870)
[M::mem_pestat] mean and std.dev: (862.46, 660.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 386, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (548.25, 448.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768922 sequences (100000118 bp) in 3.599 CPU sec, 3.924 real sec...
[M::process] read 769090 sequences (100000164 bp) in 2.376 CPU sec, 2.381 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295006, 29, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 245, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (449.85, 411.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.43, 66.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 769, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4955)
[M::mem_pestat] mean and std.dev: (1044.48, 992.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 287, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3161)
[M::mem_pestat] mean and std.dev: (479.95, 527.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770214 reads in 263.347 CPU sec, 8.478 real sec
sorting block 36, #reads = 1084039 mem = 536878704 peak = 853991424
[M::mem_process_seqs] Processed 769636 reads in 180.226 CPU sec, 5.800 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294864, 51, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 363, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (644.22, 705.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.66, 66.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 577, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4468)
[M::mem_pestat] mean and std.dev: (757.16, 621.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 400, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (444.44, 387.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1084786 mem = 536888016 peak = 853991424
[M::process] read 768712 sequences (100000152 bp) in 3.151 CPU sec, 3.372 real sec...
[M::process] read 769804 sequences (100000187 bp) in 2.031 CPU sec, 2.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294639, 43, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 322, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4333)
[M::mem_pestat] mean and std.dev: (707.58, 823.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.55, 66.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 748, 2641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7175)
[M::mem_pestat] mean and std.dev: (1494.17, 1614.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 244, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (434.68, 521.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768922 reads in 258.380 CPU sec, 8.370 real sec
[M::mem_process_seqs] Processed 769090 reads in 178.778 CPU sec, 5.805 real sec
sorting block 38, #reads = 1084624 mem = 536884536 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295067, 51, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 261, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (632.55, 784.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.49, 66.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 583, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3869)
[M::mem_pestat] mean and std.dev: (661.42, 685.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 307, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (357.17, 254.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771262 sequences (100000192 bp) in 3.475 CPU sec, 3.741 real sec...
[M::process] read 769072 sequences (100000253 bp) in 2.309 CPU sec, 2.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295128, 44, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 485, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (615.93, 564.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.01, 66.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 609, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4373)
[M::mem_pestat] mean and std.dev: (767.80, 790.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 436, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (593.53, 608.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768712 reads in 256.101 CPU sec, 8.247 real sec
sorting block 39, #reads = 1085586 mem = 536884987 peak = 853991424
[M::mem_process_seqs] Processed 769804 reads in 178.705 CPU sec, 5.780 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295565, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 420, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (525.98, 460.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.08, 65.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 749, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4035)
[M::mem_pestat] mean and std.dev: (956.25, 808.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 275, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (516.18, 541.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769036 sequences (100000038 bp) in 3.578 CPU sec, 3.774 real sec...
sorting block 40, #reads = 1083801 mem = 536883216 peak = 853991424
[M::process] read 768684 sequences (100000167 bp) in 1.980 CPU sec, 1.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 294355, 36, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 307, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (553.83, 604.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.45, 66.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 430, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4207)
[M::mem_pestat] mean and std.dev: (733.74, 775.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 265, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2842)
[M::mem_pestat] mean and std.dev: (530.33, 565.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771262 reads in 263.415 CPU sec, 8.560 real sec
[M::mem_process_seqs] Processed 769072 reads in 184.502 CPU sec, 6.042 real sec
sorting block 41, #reads = 1085064 mem = 536881268 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294314, 44, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 302, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588)
[M::mem_pestat] mean and std.dev: (643.27, 687.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.24, 66.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 531, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4129)
[M::mem_pestat] mean and std.dev: (799.10, 1014.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 297, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (596.94, 578.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768096 sequences (100000024 bp) in 3.450 CPU sec, 3.629 real sec...
[M::process] read 768498 sequences (100000057 bp) in 2.266 CPU sec, 2.379 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294424, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1997)
[M::mem_pestat] mean and std.dev: (394.65, 439.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.44, 66.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 324, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (382.08, 379.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 533, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (614.80, 601.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769036 reads in 263.648 CPU sec, 8.511 real sec
[M::mem_process_seqs] Processed 768684 reads in 182.297 CPU sec, 5.897 real sec
sorting block 42, #reads = 1081259 mem = 536881178 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293652, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 227, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (291.67, 263.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.76, 66.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 532, 2125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6133)
[M::mem_pestat] mean and std.dev: (925.17, 1327.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 333, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4514)
[M::mem_pestat] mean and std.dev: (868.89, 959.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769668 sequences (100000202 bp) in 3.655 CPU sec, 3.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293720, 48, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 307, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (339.75, 264.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.70, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 538, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3749)
[M::mem_pestat] mean and std.dev: (730.29, 658.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 286, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (439.14, 423.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767908 sequences (100000093 bp) in 2.152 CPU sec, 2.250 real sec...
[M::mem_process_seqs] Processed 768096 reads in 263.676 CPU sec, 8.506 real sec
sorting block 43, #reads = 1084397 mem = 536881477 peak = 853991424
[M::mem_process_seqs] Processed 768498 reads in 184.143 CPU sec, 5.949 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294269, 42, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 269, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (355.83, 294.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (160.11, 65.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 313, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (311.00, 292.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 274, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (369.73, 313.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1081209 mem = 536877962 peak = 853991424
[M::process] read 768090 sequences (100000039 bp) in 3.650 CPU sec, 3.909 real sec...
[M::process] read 768348 sequences (100000111 bp) in 2.269 CPU sec, 2.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 293816, 37, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 285, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (332.32, 290.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.68, 66.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 289, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (410.51, 444.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 302, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (578.44, 727.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769668 reads in 265.464 CPU sec, 8.550 real sec
[M::mem_process_seqs] Processed 767908 reads in 182.697 CPU sec, 5.883 real sec
sorting block 45, #reads = 1081047 mem = 536882340 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 293696, 36, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 311, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (382.96, 340.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.45, 65.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 702, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3855)
[M::mem_pestat] mean and std.dev: (715.78, 701.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 272, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5288)
[M::mem_pestat] mean and std.dev: (800.09, 1018.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767572 sequences (100000004 bp) in 3.197 CPU sec, 3.416 real sec...
[M::process] read 767640 sequences (100000155 bp) in 2.331 CPU sec, 2.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 293905, 43, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 529, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2440)
[M::mem_pestat] mean and std.dev: (532.79, 432.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.64, 66.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 466, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2658)
[M::mem_pestat] mean and std.dev: (562.03, 503.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 243, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (380.82, 354.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768090 reads in 262.139 CPU sec, 8.450 real sec
sorting block 46, #reads = 1081524 mem = 536881041 peak = 853991424
[M::mem_process_seqs] Processed 768348 reads in 180.638 CPU sec, 5.831 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293884, 35, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 373, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (478.64, 435.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.24, 66.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 556, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (481.97, 421.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 264, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (318.61, 251.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1081556 mem = 536878978 peak = 853991424
[M::process] read 767046 sequences (100000245 bp) in 3.718 CPU sec, 4.220 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 294208, 41, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 281, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (344.63, 265.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.15, 66.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 419, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (602.69, 573.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 372, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (497.32, 459.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768318 sequences (100000121 bp) in 2.312 CPU sec, 2.356 real sec...
[M::mem_process_seqs] Processed 767572 reads in 262.336 CPU sec, 8.461 real sec
[M::mem_process_seqs] Processed 767640 reads in 193.260 CPU sec, 6.234 real sec
sorting block 48, #reads = 1082466 mem = 536886756 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 293557, 47, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 315, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (371.75, 308.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.36, 66.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 539, 2054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5602)
[M::mem_pestat] mean and std.dev: (853.54, 1109.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 308, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (407.92, 328.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767440 sequences (100000179 bp) in 3.055 CPU sec, 3.410 real sec...
[M::process] read 770408 sequences (100000110 bp) in 2.128 CPU sec, 2.138 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294019, 42, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 266, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (569.34, 700.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.99, 66.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 833, 1811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4933)
[M::mem_pestat] mean and std.dev: (1107.85, 1031.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 229, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (310.92, 287.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767046 reads in 262.493 CPU sec, 8.463 real sec
sorting block 49, #reads = 1081913 mem = 536882288 peak = 853991424
[M::mem_process_seqs] Processed 768318 reads in 182.408 CPU sec, 5.896 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 293172, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 338, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (419.29, 387.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.64, 67.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 482, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (622.65, 696.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 259, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (339.54, 296.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770848 sequences (100000051 bp) in 3.466 CPU sec, 3.681 real sec...
sorting block 50, #reads = 1080810 mem = 536878298 peak = 853991424
[M::process] read 770588 sequences (100000287 bp) in 2.135 CPU sec, 2.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 294648, 39, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 333, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (638.72, 631.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.77, 65.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 773, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (677.53, 720.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 250, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (413.56, 433.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767440 reads in 267.159 CPU sec, 8.655 real sec
[M::mem_process_seqs] Processed 770408 reads in 187.679 CPU sec, 6.391 real sec
sorting block 51, #reads = 1080428 mem = 536890160 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 295089, 38, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 263, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887)
[M::mem_pestat] mean and std.dev: (368.83, 346.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.37, 65.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 724, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (760.40, 624.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 254, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (424.35, 386.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769860 sequences (100000145 bp) in 3.056 CPU sec, 3.266 real sec...
[M::process] read 768908 sequences (100000203 bp) in 2.149 CPU sec, 2.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294846, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 602, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4236)
[M::mem_pestat] mean and std.dev: (904.62, 998.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.58, 65.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 613, 2241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6393)
[M::mem_pestat] mean and std.dev: (1357.66, 1709.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8469)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 290, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (682.30, 715.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770848 reads in 264.261 CPU sec, 8.842 real sec
[M::mem_process_seqs] Processed 770588 reads in 177.950 CPU sec, 5.747 real sec
sorting block 52, #reads = 1082483 mem = 536896926 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 294684, 31, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 396, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (507.14, 449.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.17, 66.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 577, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3844)
[M::mem_pestat] mean and std.dev: (670.00, 545.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 454, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (463.11, 383.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768996 sequences (100000195 bp) in 3.062 CPU sec, 3.263 real sec...
sorting block 53, #reads = 1085720 mem = 536887331 peak = 853991424
[M::process] read 767880 sequences (100000267 bp) in 2.369 CPU sec, 2.378 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 294586, 49, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 472, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4359)
[M::mem_pestat] mean and std.dev: (968.78, 1155.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.51, 66.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 794, 1724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4646)
[M::mem_pestat] mean and std.dev: (960.34, 1012.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 371, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (584.98, 567.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769860 reads in 261.797 CPU sec, 8.513 real sec
[M::mem_process_seqs] Processed 768908 reads in 177.401 CPU sec, 5.728 real sec
sorting block 54, #reads = 1084022 mem = 536884330 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 294932, 40, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 212, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (222.74, 129.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.83, 66.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 825, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (718.17, 593.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 286, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (326.54, 214.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767806 sequences (100000039 bp) in 3.297 CPU sec, 3.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294705, 47, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 269, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (345.31, 276.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.58, 67.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 819, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3824)
[M::mem_pestat] mean and std.dev: (964.60, 962.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 419, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (634.26, 600.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768758 sequences (100000198 bp) in 2.468 CPU sec, 2.514 real sec...
[M::mem_process_seqs] Processed 768996 reads in 254.668 CPU sec, 8.194 real sec
[M::mem_process_seqs] Processed 767880 reads in 178.036 CPU sec, 5.738 real sec
sorting block 55, #reads = 1086002 mem = 536882207 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 293859, 50, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 529, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733)
[M::mem_pestat] mean and std.dev: (581.01, 493.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.26, 67.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 1081, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (893.95, 803.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 354, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3091)
[M::mem_pestat] mean and std.dev: (651.63, 765.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769828 sequences (100000226 bp) in 3.526 CPU sec, 3.691 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 294583, 33, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 342, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2387)
[M::mem_pestat] mean and std.dev: (570.92, 604.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.40, 66.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 824, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3485)
[M::mem_pestat] mean and std.dev: (659.97, 596.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 311, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (381.10, 279.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769476 sequences (100000034 bp) in 2.365 CPU sec, 2.376 real sec...
[M::mem_process_seqs] Processed 767806 reads in 255.078 CPU sec, 8.205 real sec
sorting block 56, #reads = 1083826 mem = 536878700 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 294471, 33, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 315, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (517.81, 560.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.70, 65.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 391, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (442.00, 405.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 457, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (527.80, 437.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768304 sequences (100000135 bp) in 2.559 CPU sec, 2.567 real sec...
[M::mem_process_seqs] Processed 769828 reads in 151.922 CPU sec, 4.934 real sec
sorting block 57, #reads = 1084677 mem = 536882376 peak = 853991424
[M::mem_process_seqs] Processed 768758 reads in 382.991 CPU sec, 12.423 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294525, 51, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 364, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (488.51, 437.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.32, 66.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 367, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214)
[M::mem_pestat] mean and std.dev: (402.05, 354.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 302, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (438.29, 424.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768132 sequences (100000284 bp) in 3.273 CPU sec, 3.681 real sec...
sorting block 58, #reads = 1083000 mem = 536876673 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 293957, 37, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 428, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769)
[M::mem_pestat] mean and std.dev: (667.60, 627.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.37, 65.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 1057, 2042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5444)
[M::mem_pestat] mean and std.dev: (1061.34, 972.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 344, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (461.24, 412.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767954 sequences (100000034 bp) in 2.123 CPU sec, 2.127 real sec...
[M::mem_process_seqs] Processed 769476 reads in 295.864 CPU sec, 9.558 real sec
[M::mem_process_seqs] Processed 768304 reads in 182.312 CPU sec, 5.902 real sec
sorting block 59, #reads = 1083642 mem = 536882209 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 293598, 46, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 347, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (468.47, 437.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.02, 66.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 684, 2282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6106)
[M::mem_pestat] mean and std.dev: (1296.45, 1428.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 360, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (573.82, 541.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767862 sequences (100000155 bp) in 3.281 CPU sec, 3.716 real sec...
[M::process] read 768530 sequences (100000004 bp) in 2.265 CPU sec, 2.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 293733, 27, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 470, 1820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5160)
[M::mem_pestat] mean and std.dev: (977.58, 1135.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.01, 66.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 612, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (588.17, 370.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 239, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (399.35, 329.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768132 reads in 257.610 CPU sec, 8.317 real sec
[M::mem_process_seqs] Processed 767954 reads in 178.566 CPU sec, 5.747 real sec
sorting block 60, #reads = 1081772 mem = 536879393 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293352, 37, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 290, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (694.56, 796.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.74, 66.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 476, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (704.38, 578.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (495.21, 612.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767824 sequences (100000117 bp) in 3.662 CPU sec, 4.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294171, 35, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 346, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (378.77, 326.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.91, 66.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 359, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1565)
[M::mem_pestat] mean and std.dev: (340.70, 239.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 494, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3710)
[M::mem_pestat] mean and std.dev: (616.30, 585.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767986 sequences (100000055 bp) in 2.054 CPU sec, 2.206 real sec...
[M::mem_process_seqs] Processed 767862 reads in 259.401 CPU sec, 8.392 real sec
sorting block 61, #reads = 1082418 mem = 536878909 peak = 853991424
[M::mem_process_seqs] Processed 768530 reads in 179.190 CPU sec, 5.786 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293690, 30, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 368, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (524.39, 461.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 62, #reads = 1082639 mem = 536879601 peak = 853991424
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.19, 66.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 546, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (476.32, 228.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (350.46, 308.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768060 sequences (100000027 bp) in 3.328 CPU sec, 3.842 real sec...
[M::process] read 767824 sequences (100000104 bp) in 2.199 CPU sec, 2.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293795, 38, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 249, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (577.43, 621.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.72, 66.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 488, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4245)
[M::mem_pestat] mean and std.dev: (831.19, 940.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 268, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1745)
[M::mem_pestat] mean and std.dev: (410.89, 399.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767824 reads in 258.572 CPU sec, 8.327 real sec
[M::mem_process_seqs] Processed 767986 reads in 179.416 CPU sec, 5.785 real sec
sorting block 63, #reads = 1081357 mem = 536879756 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293893, 44, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 349, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (715.03, 719.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (160.09, 65.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 607, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (768.43, 722.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 411, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2992)
[M::mem_pestat] mean and std.dev: (543.20, 508.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767408 sequences (100000293 bp) in 3.449 CPU sec, 3.734 real sec...
[M::process] read 767136 sequences (100000091 bp) in 2.099 CPU sec, 2.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 293567, 45, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 231, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2304)
[M::mem_pestat] mean and std.dev: (377.42, 392.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.69, 66.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 763, 2516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7240)
[M::mem_pestat] mean and std.dev: (1308.28, 1603.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 239, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (309.70, 211.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768060 reads in 259.384 CPU sec, 8.351 real sec
sorting block 64, #reads = 1081284 mem = 536881872 peak = 853991424
[M::mem_process_seqs] Processed 767824 reads in 179.200 CPU sec, 5.792 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293638, 44, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 221, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (274.67, 176.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.31, 66.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 638, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4712)
[M::mem_pestat] mean and std.dev: (810.17, 995.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6202)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 452, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4458)
[M::mem_pestat] mean and std.dev: (907.28, 898.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1082269 mem = 536879691 peak = 853991424
[M::process] read 767224 sequences (100000183 bp) in 2.973 CPU sec, 3.253 real sec...
[M::process] read 766746 sequences (100000088 bp) in 2.245 CPU sec, 2.313 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 294131, 52, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 308, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3845)
[M::mem_pestat] mean and std.dev: (669.72, 775.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.74, 67.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 950, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5295)
[M::mem_pestat] mean and std.dev: (1051.66, 969.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 518, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (659.63, 576.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767408 reads in 255.059 CPU sec, 8.238 real sec
[M::process] read 772830 sequences (100000093 bp) in 2.432 CPU sec, 2.457 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293422, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 183, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (253.12, 202.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.72, 67.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 570, 1518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3822)
[M::mem_pestat] mean and std.dev: (815.15, 755.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 415, 1654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4532)
[M::mem_pestat] mean and std.dev: (930.39, 1045.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767224 reads in 152.082 CPU sec, 5.211 real sec
sorting block 66, #reads = 1081242 mem = 536879000 peak = 853991424
[M::mem_process_seqs] Processed 767136 reads in 377.104 CPU sec, 12.477 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293046, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 252, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (381.28, 345.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.07, 67.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 636, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (700.65, 501.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 372, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4635)
[M::mem_pestat] mean and std.dev: (822.07, 882.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1080158 mem = 536880206 peak = 853991424
[M::process] read 776272 sequences (100000119 bp) in 3.334 CPU sec, 3.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 295940, 45, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 263, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (479.87, 505.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.60, 64.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 500, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3555)
[M::mem_pestat] mean and std.dev: (612.17, 635.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 290, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (361.02, 288.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775056 sequences (100000084 bp) in 2.019 CPU sec, 2.033 real sec...
[M::mem_process_seqs] Processed 766746 reads in 296.936 CPU sec, 9.600 real sec
[M::mem_process_seqs] Processed 772830 reads in 186.497 CPU sec, 6.002 real sec
sorting block 68, #reads = 1082029 mem = 536880078 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296887, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 543, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5202)
[M::mem_pestat] mean and std.dev: (1007.78, 1148.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 361)
[M::mem_pestat] mean and std.dev: (155.04, 61.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 445)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 755, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4419)
[M::mem_pestat] mean and std.dev: (893.17, 944.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 294, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (318.83, 281.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775074 sequences (100000163 bp) in 3.357 CPU sec, 4.089 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296847, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 461, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (660.12, 664.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.61, 62.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 504, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (653.12, 616.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 489, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (693.04, 730.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774402 sequences (100000010 bp) in 2.481 CPU sec, 2.494 real sec...
[M::mem_process_seqs] Processed 776272 reads in 267.694 CPU sec, 8.622 real sec
sorting block 69, #reads = 1083202 mem = 536878363 peak = 853991424
[M::mem_process_seqs] Processed 775056 reads in 182.305 CPU sec, 5.867 real sec
sorting block 70, #reads = 1086191 mem = 536887479 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 297233, 38, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 578, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (605.96, 494.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.68, 62.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 619, 2240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6338)
[M::mem_pestat] mean and std.dev: (1500.13, 1800.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8704)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 386, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (494.28, 460.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773286 sequences (100000251 bp) in 3.425 CPU sec, 3.781 real sec...
[M::process] read 772542 sequences (100000142 bp) in 1.880 CPU sec, 1.883 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296236, 35, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 371, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (435.79, 365.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.60, 63.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 776, 1952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4930)
[M::mem_pestat] mean and std.dev: (1027.23, 1018.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 373, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (472.08, 353.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 775074 reads in 251.165 CPU sec, 8.074 real sec
[M::mem_process_seqs] Processed 774402 reads in 171.906 CPU sec, 5.491 real sec
sorting block 71, #reads = 1084233 mem = 536879818 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296001, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 267, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (474.45, 521.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.40, 63.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 534, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4511)
[M::mem_pestat] mean and std.dev: (949.57, 1011.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 293, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (355.50, 318.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772398 sequences (100000058 bp) in 3.235 CPU sec, 3.365 real sec...
[M::process] read 774438 sequences (100000000 bp) in 2.090 CPU sec, 2.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 296236, 36, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 433, 2877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8261)
[M::mem_pestat] mean and std.dev: (1242.49, 1367.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.76, 64.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 900, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5793)
[M::mem_pestat] mean and std.dev: (1145.94, 1398.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 341, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (463.56, 430.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773286 reads in 248.259 CPU sec, 7.915 real sec
sorting block 72, #reads = 1083772 mem = 536890263 peak = 853991424
[M::mem_process_seqs] Processed 772542 reads in 171.579 CPU sec, 5.500 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296252, 41, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 446, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (546.98, 485.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.06, 64.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 834, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (1166.60, 952.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 250, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186)
[M::mem_pestat] mean and std.dev: (430.98, 428.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 73, #reads = 1084302 mem = 536878157 peak = 853991424
[M::process] read 775528 sequences (100000236 bp) in 3.486 CPU sec, 3.682 real sec...
[M::process] read 775380 sequences (100000104 bp) in 2.088 CPU sec, 2.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296735, 36, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 371, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (518.02, 471.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.59, 63.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 1075, 3219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8579)
[M::mem_pestat] mean and std.dev: (1767.49, 1958.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 416, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (400.09, 254.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772398 reads in 248.382 CPU sec, 7.953 real sec
[M::mem_process_seqs] Processed 774438 reads in 171.939 CPU sec, 5.515 real sec
sorting block 74, #reads = 1083798 mem = 536888586 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297117, 39, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 285, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (539.41, 530.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.51, 62.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 592, 2473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6807)
[M::mem_pestat] mean and std.dev: (1040.17, 1147.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 317, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (387.84, 286.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775350 sequences (100000048 bp) in 3.524 CPU sec, 3.676 real sec...
[M::process] read 775076 sequences (100000149 bp) in 2.309 CPU sec, 2.309 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296866, 32, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (327.89, 301.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.58, 62.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 627, 2568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7256)
[M::mem_pestat] mean and std.dev: (1347.37, 1845.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 654, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4436)
[M::mem_pestat] mean and std.dev: (868.70, 930.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 775528 reads in 255.250 CPU sec, 8.152 real sec
sorting block 75, #reads = 1084676 mem = 536881699 peak = 853991424
[M::mem_process_seqs] Processed 775380 reads in 180.211 CPU sec, 5.772 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296578, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 250, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (436.81, 407.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.58, 62.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 350, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4326)
[M::mem_pestat] mean and std.dev: (507.41, 561.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 305, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (399.98, 372.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773630 sequences (100000153 bp) in 3.259 CPU sec, 3.414 real sec...
sorting block 76, #reads = 1082353 mem = 536882849 peak = 853991424
[M::process] read 772448 sequences (100000121 bp) in 2.090 CPU sec, 2.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296567, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 213, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (295.90, 311.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.06, 62.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 986, 2285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5803)
[M::mem_pestat] mean and std.dev: (1288.91, 1201.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 245, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (365.70, 324.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 775350 reads in 260.920 CPU sec, 8.355 real sec
[M::mem_process_seqs] Processed 775076 reads in 182.805 CPU sec, 5.860 real sec
sorting block 77, #reads = 1079935 mem = 536880096 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 296734, 42, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 258, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (486.94, 473.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.05, 63.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 771, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3842)
[M::mem_pestat] mean and std.dev: (888.40, 775.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 933, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610)
[M::mem_pestat] mean and std.dev: (898.63, 727.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 778882 sequences (100000093 bp) in 3.399 CPU sec, 3.537 real sec...
[M::process] read 774480 sequences (100000083 bp) in 2.241 CPU sec, 2.246 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296145, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 323, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (323.19, 258.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.33, 63.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 1204, 2926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8196)
[M::mem_pestat] mean and std.dev: (1373.42, 1589.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 564, 1788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4946)
[M::mem_pestat] mean and std.dev: (900.94, 955.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773630 reads in 246.505 CPU sec, 7.872 real sec
[M::mem_process_seqs] Processed 772448 reads in 171.230 CPU sec, 5.488 real sec
sorting block 78, #reads = 1080952 mem = 536880179 peak = 853991424
[M::process] read 772936 sequences (100000091 bp) in 3.062 CPU sec, 3.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 296716, 30, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 248, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2075)
[M::mem_pestat] mean and std.dev: (420.00, 499.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357)
[M::mem_pestat] mean and std.dev: (153.61, 61.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 440)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 700, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5728)
[M::mem_pestat] mean and std.dev: (1026.50, 1023.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 309, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (477.74, 443.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772020 sequences (100000177 bp) in 2.192 CPU sec, 2.198 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295848, 41, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 317, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (343.77, 243.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.33, 63.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 796, 1844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5052)
[M::mem_pestat] mean and std.dev: (1007.34, 1095.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 352, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (517.90, 500.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295337, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 349, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (447.56, 380.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.31, 63.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 492, 2345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6897)
[M::mem_pestat] mean and std.dev: (1093.52, 1162.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 273, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (524.39, 562.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 778882 reads in 365.489 CPU sec, 11.696 real sec
sorting block 79, #reads = 1082167 mem = 536879104 peak = 853991424
[M::mem_process_seqs] Processed 774480 reads in 270.736 CPU sec, 8.702 real sec
[M::mem_process_seqs] Processed 772936 reads in 309.163 CPU sec, 9.945 real sec
sorting block 80, #reads = 1067640 mem = 536883145 peak = 853991424
[M::process] read 772478 sequences (100000128 bp) in 3.403 CPU sec, 3.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 294430, 43, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 574, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3845)
[M::mem_pestat] mean and std.dev: (599.00, 670.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.77, 63.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 355, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4304)
[M::mem_pestat] mean and std.dev: (699.20, 831.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 609, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (591.05, 561.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 81, #reads = 1072592 mem = 536881115 peak = 853991424
[M::process] read 771508 sequences (100000027 bp) in 2.863 CPU sec, 3.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 295126, 24, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 409, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252)
[M::mem_pestat] mean and std.dev: (517.43, 500.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.44, 63.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 538, 3312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9568)
[M::mem_pestat] mean and std.dev: (1783.71, 2263.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 379, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3501)
[M::mem_pestat] mean and std.dev: (622.33, 709.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771698 sequences (100000005 bp) in 2.199 CPU sec, 2.197 real sec...
[M::mem_process_seqs] Processed 772020 reads in 268.051 CPU sec, 8.556 real sec
[M::mem_process_seqs] Processed 772478 reads in 186.814 CPU sec, 5.951 real sec
sorting block 82, #reads = 1076600 mem = 536881680 peak = 853991424
[M::process] read 770562 sequences (100000085 bp) in 2.634 CPU sec, 2.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 294857, 35, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 394, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (491.79, 434.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.16, 64.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 759, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4188)
[M::mem_pestat] mean and std.dev: (991.68, 1099.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 355, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (530.98, 497.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771508 reads in 156.892 CPU sec, 5.075 real sec
sorting block 83, #reads = 1074709 mem = 536876148 peak = 853991424
[M::process] read 784054 sequences (100000051 bp) in 2.723 CPU sec, 2.810 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 293822, 49, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 390, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (422.80, 331.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.24, 64.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 342, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (617.17, 671.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 303, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (489.19, 417.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 778902 sequences (100000290 bp) in 2.387 CPU sec, 2.397 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293738, 36, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 267, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1664)
[M::mem_pestat] mean and std.dev: (371.62, 347.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.68, 63.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 583, 2785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7955)
[M::mem_pestat] mean and std.dev: (1450.21, 1875.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 284, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (379.39, 402.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770562 reads in 318.930 CPU sec, 10.273 real sec
[M::mem_process_seqs] Processed 771698 reads in 359.101 CPU sec, 11.603 real sec
sorting block 84, #reads = 1073712 mem = 536883242 peak = 853991424
[M::process] read 776818 sequences (100000009 bp) in 2.841 CPU sec, 2.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 298535, 30, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 196, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (377.04, 372.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (106, 140, 187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 349)
[M::mem_pestat] mean and std.dev: (150.79, 59.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 430)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 393, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (709.81, 738.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 288, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2046)
[M::mem_pestat] mean and std.dev: (456.16, 389.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 777034 sequences (100000152 bp) in 2.027 CPU sec, 2.036 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 297127, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 212, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1322)
[M::mem_pestat] mean and std.dev: (306.91, 278.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 361)
[M::mem_pestat] mean and std.dev: (154.90, 61.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 445)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 541, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4275)
[M::mem_pestat] mean and std.dev: (621.87, 645.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 450, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (717.05, 848.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 297128, 29, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 330, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (448.22, 416.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357)
[M::mem_pestat] mean and std.dev: (153.52, 60.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 440)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 671, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (692.61, 630.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 309, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (451.08, 421.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 784054 reads in 398.795 CPU sec, 12.807 real sec
sorting block 85, #reads = 1070284 mem = 536883751 peak = 853991424
[M::mem_process_seqs] Processed 776818 reads in 306.418 CPU sec, 9.854 real sec
[M::mem_process_seqs] Processed 778902 reads in 346.988 CPU sec, 11.177 real sec
sorting block 86, #reads = 1069742 mem = 536880463 peak = 853991424
[M::process] read 774654 sequences (100000226 bp) in 3.699 CPU sec, 3.894 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297127, 37, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 271, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (413.11, 418.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.83, 62.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 250, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2367)
[M::mem_pestat] mean and std.dev: (350.85, 347.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (316.20, 276.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1073462 mem = 536880215 peak = 853991424
[M::process] read 773284 sequences (100000298 bp) in 2.990 CPU sec, 3.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296278, 41, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 214, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (273.85, 189.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.42, 63.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 818, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5794)
[M::mem_pestat] mean and std.dev: (1218.49, 1003.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 274, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (652.43, 784.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772436 sequences (100000082 bp) in 2.105 CPU sec, 2.114 real sec...
[M::mem_process_seqs] Processed 777034 reads in 266.905 CPU sec, 8.529 real sec
[M::mem_process_seqs] Processed 774654 reads in 183.932 CPU sec, 5.841 real sec
sorting block 88, #reads = 1077293 mem = 536882872 peak = 853991424
[M::process] read 774118 sequences (100000292 bp) in 2.652 CPU sec, 2.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295822, 29, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 303, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (528.88, 615.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.11, 63.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 614, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (707.65, 588.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (465.38, 403.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773490 sequences (100000095 bp) in 1.743 CPU sec, 1.747 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 297127, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 409, 1972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5544)
[M::mem_pestat] mean and std.dev: (868.49, 1089.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.72, 63.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 560, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3988)
[M::mem_pestat] mean and std.dev: (725.00, 710.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 320, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (406.19, 374.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296242, 38, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 344, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259)
[M::mem_pestat] mean and std.dev: (508.10, 557.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.85, 64.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 632, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (639.23, 558.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 308, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (451.94, 380.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773284 reads in 329.160 CPU sec, 10.720 real sec
sorting block 89, #reads = 1078388 mem = 536880138 peak = 853991424
[M::mem_process_seqs] Processed 774118 reads in 260.782 CPU sec, 8.401 real sec
[M::mem_process_seqs] Processed 772436 reads in 292.099 CPU sec, 9.427 real sec
[M::process] read 773930 sequences (100000122 bp) in 3.052 CPU sec, 3.228 real sec...
sorting block 90, #reads = 1082388 mem = 536882331 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296423, 43, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 395, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (446.67, 363.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.20, 63.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 459, 1955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5521)
[M::mem_pestat] mean and std.dev: (1141.46, 1453.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7304)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 363, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (623.32, 639.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773312 sequences (100000082 bp) in 2.928 CPU sec, 3.114 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296881, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 395, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (748.49, 800.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.97, 63.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 447, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2968)
[M::mem_pestat] mean and std.dev: (542.80, 560.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 299, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3755)
[M::mem_pestat] mean and std.dev: (599.98, 676.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4948)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774298 sequences (100000274 bp) in 2.211 CPU sec, 2.226 real sec...
[M::mem_process_seqs] Processed 773490 reads in 272.469 CPU sec, 8.752 real sec
sorting block 91, #reads = 1081231 mem = 536878402 peak = 853991424
[M::mem_process_seqs] Processed 773930 reads in 191.279 CPU sec, 6.138 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296382, 30, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 396, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (372.34, 295.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.09, 63.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 929, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4647)
[M::mem_pestat] mean and std.dev: (943.89, 713.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 390, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (463.63, 315.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 92, #reads = 1082660 mem = 536878709 peak = 853991424
[M::process] read 773884 sequences (100000181 bp) in 3.316 CPU sec, 3.564 real sec...
[M::process] read 775896 sequences (100000202 bp) in 2.201 CPU sec, 2.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296101, 39, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 236, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (366.27, 307.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.42, 62.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 826, 1581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3909)
[M::mem_pestat] mean and std.dev: (906.20, 751.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 273, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (368.27, 281.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773312 reads in 281.895 CPU sec, 9.260 real sec
[M::mem_process_seqs] Processed 774298 reads in 202.207 CPU sec, 6.624 real sec
sorting block 93, #reads = 1083189 mem = 536884233 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 295680, 34, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 550, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4496)
[M::mem_pestat] mean and std.dev: (908.50, 929.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.85, 63.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 716, 1692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4536)
[M::mem_pestat] mean and std.dev: (998.03, 1226.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 332, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (420.29, 379.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773738 sequences (100000090 bp) in 3.280 CPU sec, 3.577 real sec...
[M::process] read 770768 sequences (100000282 bp) in 2.443 CPU sec, 2.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 295871, 43, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 309, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (591.51, 598.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (155.11, 62.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 1144, 3061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8673)
[M::mem_pestat] mean and std.dev: (1652.57, 1908.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 364, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (466.53, 457.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773884 reads in 301.570 CPU sec, 9.815 real sec
sorting block 94, #reads = 1079159 mem = 536879452 peak = 853991424
[M::mem_process_seqs] Processed 775896 reads in 236.761 CPU sec, 7.721 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 295060, 42, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 399, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2986)
[M::mem_pestat] mean and std.dev: (420.42, 399.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.74, 63.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 399, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (560.64, 604.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 263, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (343.44, 243.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770592 sequences (100000032 bp) in 3.361 CPU sec, 3.634 real sec...
sorting block 95, #reads = 1069888 mem = 536885505 peak = 853991424
[M::process] read 770630 sequences (100000109 bp) in 2.185 CPU sec, 2.230 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294368, 35, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 297, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (490.17, 470.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.38, 64.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 518, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3794)
[M::mem_pestat] mean and std.dev: (836.26, 910.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 381, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (433.60, 318.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773738 reads in 287.053 CPU sec, 9.281 real sec
[M::mem_process_seqs] Processed 770768 reads in 194.962 CPU sec, 6.311 real sec
sorting block 96, #reads = 1072909 mem = 536885882 peak = 853991424
[M::process] read 770716 sequences (100000019 bp) in 2.934 CPU sec, 3.078 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294422, 37, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 418, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (595.50, 599.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.40, 64.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 553, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (477.42, 307.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 348, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881)
[M::mem_pestat] mean and std.dev: (534.81, 489.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770648 sequences (100000137 bp) in 1.994 CPU sec, 1.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294689, 38, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 326, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (522.46, 590.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.49, 64.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 452, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (454.50, 295.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 409, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (460.47, 326.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294312, 36, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 286, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (298.17, 281.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.48, 64.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 411, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (679.74, 593.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 448, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3784)
[M::mem_pestat] mean and std.dev: (846.75, 899.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770592 reads in 363.993 CPU sec, 12.035 real sec
sorting block 97, #reads = 1078558 mem = 536880356 peak = 853991424
[M::mem_process_seqs] Processed 770716 reads in 282.498 CPU sec, 9.091 real sec
[M::mem_process_seqs] Processed 770630 reads in 318.822 CPU sec, 10.271 real sec
[M::process] read 769930 sequences (100000058 bp) in 3.239 CPU sec, 3.428 real sec...
sorting block 98, #reads = 1079807 mem = 536881756 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294402, 36, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 472, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (694.52, 808.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.50, 64.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 533, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (629.27, 657.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 321, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (570.49, 599.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772896 sequences (100000084 bp) in 2.616 CPU sec, 2.749 real sec...
[M::process] read 776080 sequences (100000220 bp) in 1.920 CPU sec, 1.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 293946, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 407, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (673.03, 717.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.92, 64.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 572, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2789)
[M::mem_pestat] mean and std.dev: (523.83, 431.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 299, 2097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5969)
[M::mem_pestat] mean and std.dev: (915.92, 1226.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770648 reads in 261.865 CPU sec, 8.380 real sec
sorting block 99, #reads = 1080250 mem = 536880165 peak = 853991424
[M::mem_process_seqs] Processed 769930 reads in 179.166 CPU sec, 5.762 real sec
sorting block 100, #reads = 1078399 mem = 536880529 peak = 853991424
[M::process] read 773788 sequences (100000047 bp) in 2.894 CPU sec, 3.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 294204, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 300, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (503.81, 606.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.80, 63.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 458, 1987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5659)
[M::mem_pestat] mean and std.dev: (944.19, 1143.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 381, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2684)
[M::mem_pestat] mean and std.dev: (602.84, 562.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773312 sequences (100000244 bp) in 1.750 CPU sec, 1.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296382, 25, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 262, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (457.88, 471.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.71, 63.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 450, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3179)
[M::mem_pestat] mean and std.dev: (620.32, 476.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 336, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2338)
[M::mem_pestat] mean and std.dev: (478.74, 478.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297155, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 408, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4180)
[M::mem_pestat] mean and std.dev: (886.80, 1101.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.35, 62.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 562, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4052)
[M::mem_pestat] mean and std.dev: (1050.89, 1155.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 275, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2296)
[M::mem_pestat] mean and std.dev: (506.51, 468.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772896 reads in 374.911 CPU sec, 12.055 real sec
[M::mem_process_seqs] Processed 773788 reads in 276.182 CPU sec, 8.900 real sec
[M::mem_process_seqs] Processed 776080 reads in 310.629 CPU sec, 10.036 real sec
sorting block 101, #reads = 1066092 mem = 536881241 peak = 853991424
[M::process] read 772824 sequences (100000030 bp) in 3.107 CPU sec, 3.310 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 295624, 35, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 278, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (417.32, 381.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.92, 63.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 371, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (582.81, 474.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 279, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (353.64, 288.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 102, #reads = 1085073 mem = 536883159 peak = 853991424
[M::process] read 770524 sequences (100000013 bp) in 2.804 CPU sec, 2.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296046, 22, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 306, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (614.85, 729.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.52, 64.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 485, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (543.68, 507.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 302, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (482.96, 468.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770426 sequences (100000012 bp) in 2.110 CPU sec, 2.106 real sec...
[M::mem_process_seqs] Processed 773312 reads in 252.607 CPU sec, 8.074 real sec
[M::mem_process_seqs] Processed 772824 reads in 173.918 CPU sec, 5.546 real sec
sorting block 103, #reads = 1084945 mem = 536884799 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295739, 38, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 306, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (473.91, 479.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.55, 65.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 587, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (622.31, 454.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 660, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (728.43, 613.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770932 sequences (100000000 bp) in 2.947 CPU sec, 3.147 real sec...
[M::process] read 772080 sequences (100000131 bp) in 2.253 CPU sec, 2.262 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 295894, 40, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083)
[M::mem_pestat] mean and std.dev: (529.24, 644.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.05, 65.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 607, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (674.39, 592.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 310, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (560.40, 528.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770524 reads in 247.609 CPU sec, 7.916 real sec
sorting block 104, #reads = 1085089 mem = 536879092 peak = 853991424
[M::mem_process_seqs] Processed 770426 reads in 168.632 CPU sec, 5.560 real sec
sorting block 105, #reads = 1084421 mem = 536881948 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295856, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 497, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3842)
[M::mem_pestat] mean and std.dev: (613.31, 604.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.87, 64.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 545, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5260)
[M::mem_pestat] mean and std.dev: (969.79, 1229.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 449, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (542.78, 438.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773676 sequences (100000072 bp) in 3.021 CPU sec, 3.166 real sec...
[M::process] read 772102 sequences (100000278 bp) in 2.115 CPU sec, 2.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 296160, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 237, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2208)
[M::mem_pestat] mean and std.dev: (461.88, 526.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.86, 64.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 570, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2439)
[M::mem_pestat] mean and std.dev: (611.46, 489.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 239, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (424.87, 435.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770932 reads in 237.221 CPU sec, 7.721 real sec
[M::mem_process_seqs] Processed 772080 reads in 158.368 CPU sec, 5.060 real sec
sorting block 106, #reads = 1086464 mem = 536878375 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 296530, 34, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 408, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2964)
[M::mem_pestat] mean and std.dev: (701.54, 804.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.78, 63.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 519, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (469.93, 358.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 322, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (422.74, 347.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772030 sequences (100000011 bp) in 2.977 CPU sec, 3.130 real sec...
[M::process] read 771542 sequences (100000278 bp) in 2.199 CPU sec, 2.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295961, 34, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 253, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (384.53, 335.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.65, 63.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 844, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4135)
[M::mem_pestat] mean and std.dev: (904.30, 888.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 283, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2202)
[M::mem_pestat] mean and std.dev: (397.39, 367.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773676 reads in 241.884 CPU sec, 7.885 real sec
sorting block 107, #reads = 1086611 mem = 536883931 peak = 853991424
[M::mem_process_seqs] Processed 772102 reads in 162.299 CPU sec, 5.382 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 296233, 29, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 294, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (392.50, 344.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 770524 sequences (100000201 bp) in 3.040 CPU sec, 3.278 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.74, 64.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 511, 1788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5272)
[M::mem_pestat] mean and std.dev: (769.59, 979.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 291, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (442.12, 391.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 108, #reads = 1085955 mem = 536883211 peak = 853991424
[M::mem_process_seqs] Processed 772030 reads in 140.515 CPU sec, 4.723 real sec
[M::process] read 769924 sequences (100000041 bp) in 2.554 CPU sec, 2.704 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295377, 31, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 226, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (434.60, 572.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.20, 64.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 363, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (402.85, 411.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 269, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (320.75, 230.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770786 sequences (100000108 bp) in 2.085 CPU sec, 2.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294995, 30, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 315, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (550.36, 593.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.40, 64.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 1001, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4528)
[M::mem_pestat] mean and std.dev: (905.52, 762.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 393, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2761)
[M::mem_pestat] mean and std.dev: (524.00, 429.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 294363, 44, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 243, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (295.84, 231.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.08, 64.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 760, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4936)
[M::mem_pestat] mean and std.dev: (718.17, 834.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 357, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (505.28, 479.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771542 reads in 346.063 CPU sec, 11.102 real sec
sorting block 109, #reads = 1083632 mem = 536879670 peak = 853991424
[M::mem_process_seqs] Processed 770524 reads in 235.658 CPU sec, 7.592 real sec
[M::mem_process_seqs] Processed 769924 reads in 260.112 CPU sec, 8.394 real sec
sorting block 110, #reads = 1083006 mem = 536884244 peak = 853991424
[M::process] read 771166 sequences (100000224 bp) in 2.717 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 294335, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 385, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3391)
[M::mem_pestat] mean and std.dev: (495.80, 591.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.32, 64.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 437, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (535.34, 583.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 399, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (605.97, 534.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770822 sequences (100000136 bp) in 2.769 CPU sec, 2.888 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 294409, 24, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 307, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (504.30, 552.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (158.03, 63.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 563, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4241)
[M::mem_pestat] mean and std.dev: (885.95, 806.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 356, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254)
[M::mem_pestat] mean and std.dev: (423.27, 351.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769880 sequences (100000258 bp) in 1.980 CPU sec, 1.979 real sec...
[M::mem_process_seqs] Processed 770786 reads in 231.125 CPU sec, 7.368 real sec
sorting block 111, #reads = 1083018 mem = 536877077 peak = 853991424
[M::mem_process_seqs] Processed 771166 reads in 164.897 CPU sec, 5.254 real sec
sorting block 112, #reads = 1074796 mem = 536880233 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 294351, 46, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 326, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (554.54, 617.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.28, 64.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 833, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3797)
[M::mem_pestat] mean and std.dev: (1008.55, 784.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 291, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (413.35, 393.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770842 sequences (100000191 bp) in 2.921 CPU sec, 3.084 real sec...
[M::process] read 770286 sequences (100000031 bp) in 2.135 CPU sec, 2.138 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293316, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 347, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (501.72, 467.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.88, 64.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 504, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2178)
[M::mem_pestat] mean and std.dev: (420.14, 452.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 329, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (496.76, 472.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770822 reads in 228.476 CPU sec, 7.276 real sec
sorting block 113, #reads = 1077452 mem = 536885469 peak = 853991424
[M::mem_process_seqs] Processed 769880 reads in 161.917 CPU sec, 5.539 real sec
[M::process] read 770946 sequences (100000143 bp) in 2.548 CPU sec, 2.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 294236, 37, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 216, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (261.10, 180.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (158.09, 63.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 747, 3164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9114)
[M::mem_pestat] mean and std.dev: (1792.51, 2335.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 310, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (660.66, 773.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770262 sequences (100000088 bp) in 1.578 CPU sec, 1.580 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 294253, 47, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 344, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (471.62, 429.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.19, 64.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 427, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (551.79, 642.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 376, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (636.00, 684.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 294047, 27, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (295.77, 224.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.34, 64.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 850, 2097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5869)
[M::mem_pestat] mean and std.dev: (1226.88, 1315.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 319, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (432.13, 458.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3617)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770842 reads in 313.461 CPU sec, 10.386 real sec
sorting block 114, #reads = 1078653 mem = 536886955 peak = 853991424
[M::mem_process_seqs] Processed 770946 reads in 243.690 CPU sec, 7.840 real sec
[M::mem_process_seqs] Processed 770286 reads in 271.067 CPU sec, 8.735 real sec
sorting block 115, #reads = 1078833 mem = 536878581 peak = 853991424
[M::process] read 776658 sequences (100000152 bp) in 3.341 CPU sec, 3.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293634, 37, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 423, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (531.80, 445.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.51, 64.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 565, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (745.17, 819.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 213, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (248.07, 178.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770262 reads in 124.103 CPU sec, 4.078 real sec
sorting block 116, #reads = 1077276 mem = 536878958 peak = 853991424
[M::process] read 778496 sequences (100000116 bp) in 3.627 CPU sec, 3.998 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 296130, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 272, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (451.02, 468.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.84, 61.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 558, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (830.73, 927.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 468, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3750)
[M::mem_pestat] mean and std.dev: (668.62, 667.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775824 sequences (100000080 bp) in 1.903 CPU sec, 1.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296812, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 230, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (433.15, 418.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (153.90, 61.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 991, 1712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4556)
[M::mem_pestat] mean and std.dev: (1028.57, 1014.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 549, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (529.27, 495.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774170 sequences (100000007 bp) in 1.640 CPU sec, 1.640 real sec...
[M::mem_process_seqs] Processed 776658 reads in 247.943 CPU sec, 7.951 real sec
sorting block 117, #reads = 1066227 mem = 536887536 peak = 853991424
[M::mem_process_seqs] Processed 778496 reads in 146.486 CPU sec, 4.910 real sec
sorting block 118, #reads = 1075277 mem = 536879233 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296689, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 242, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (450.33, 441.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.53, 62.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 1040, 2142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5786)
[M::mem_pestat] mean and std.dev: (1290.15, 1208.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 266, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (374.94, 339.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773580 sequences (100000126 bp) in 3.302 CPU sec, 3.564 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296186, 27, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 342, 1736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4894)
[M::mem_pestat] mean and std.dev: (967.06, 1333.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.31, 62.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 1048, 3673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9995)
[M::mem_pestat] mean and std.dev: (2430.15, 2830.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 366, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (492.38, 402.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772058 sequences (100000257 bp) in 1.950 CPU sec, 1.955 real sec...
[M::mem_process_seqs] Processed 775824 reads in 213.397 CPU sec, 7.048 real sec
[M::mem_process_seqs] Processed 774170 reads in 143.884 CPU sec, 4.597 real sec
sorting block 119, #reads = 1078399 mem = 536889242 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296276, 28, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 199, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (397.83, 419.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.95, 63.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 777, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3818)
[M::mem_pestat] mean and std.dev: (793.04, 791.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 391, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (456.64, 389.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771778 sequences (100000125 bp) in 2.839 CPU sec, 3.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296077, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 352, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2344)
[M::mem_pestat] mean and std.dev: (495.86, 456.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.92, 64.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 638, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (615.83, 424.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (304.26, 217.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771300 sequences (100000257 bp) in 1.850 CPU sec, 1.849 real sec...
[M::mem_process_seqs] Processed 773580 reads in 202.245 CPU sec, 6.463 real sec
sorting block 120, #reads = 1079433 mem = 536880415 peak = 853991424
[M::mem_process_seqs] Processed 772058 reads in 137.353 CPU sec, 4.551 real sec
sorting block 121, #reads = 1081049 mem = 536881256 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295496, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 335, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1862)
[M::mem_pestat] mean and std.dev: (363.28, 310.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.14, 64.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 717, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (797.90, 588.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 355, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2968)
[M::mem_pestat] mean and std.dev: (537.49, 539.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772174 sequences (100000131 bp) in 2.852 CPU sec, 3.047 real sec...
[M::process] read 770726 sequences (100000119 bp) in 1.800 CPU sec, 1.803 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 295378, 38, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 219, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (380.57, 400.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.35, 64.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 626, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (649.81, 423.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 251, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (368.97, 320.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771778 reads in 200.966 CPU sec, 6.569 real sec
[M::mem_process_seqs] Processed 771300 reads in 134.002 CPU sec, 4.286 real sec
sorting block 122, #reads = 1082765 mem = 536884513 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295772, 32, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 228, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (386.65, 396.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.81, 64.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 475, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181)
[M::mem_pestat] mean and std.dev: (676.94, 639.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 392, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (642.15, 679.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769990 sequences (100000010 bp) in 3.073 CPU sec, 3.324 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295412, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 308, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (317.75, 239.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 770294 sequences (100000060 bp) in 1.540 CPU sec, 1.544 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.91, 65.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 544, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3616)
[M::mem_pestat] mean and std.dev: (546.27, 446.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 300, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (375.31, 297.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772174 reads in 204.994 CPU sec, 6.675 real sec
sorting block 123, #reads = 1082501 mem = 536880653 peak = 853991424
[M::mem_process_seqs] Processed 770726 reads in 136.554 CPU sec, 4.538 real sec
sorting block 124, #reads = 1083172 mem = 536881047 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 293962, 34, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 483, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (743.73, 621.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.26, 65.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 612, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (611.56, 682.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 322, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (594.27, 540.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768628 sequences (100000000 bp) in 2.501 CPU sec, 2.651 real sec...
[M::process] read 768170 sequences (100000055 bp) in 1.620 CPU sec, 1.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 294061, 49, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 272, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (366.69, 330.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.28, 65.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 547, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4037)
[M::mem_pestat] mean and std.dev: (944.17, 1021.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 401, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2127)
[M::mem_pestat] mean and std.dev: (506.59, 458.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769990 reads in 209.024 CPU sec, 6.829 real sec
[M::mem_process_seqs] Processed 770294 reads in 143.178 CPU sec, 4.602 real sec
sorting block 125, #reads = 1079857 mem = 536877620 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 292829, 44, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 263, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (456.71, 453.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.88, 65.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 405, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (550.70, 594.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 441, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3445)
[M::mem_pestat] mean and std.dev: (738.71, 744.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768064 sequences (100000009 bp) in 2.568 CPU sec, 2.722 real sec...
[M::process] read 767116 sequences (100000184 bp) in 1.570 CPU sec, 1.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 292865, 34, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 208, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (245.15, 183.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.64, 66.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 547, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3877)
[M::mem_pestat] mean and std.dev: (632.39, 676.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 253, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (288.15, 176.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768628 reads in 208.975 CPU sec, 6.682 real sec
[M::mem_process_seqs] Processed 768170 reads in 138.057 CPU sec, 4.425 real sec
sorting block 126, #reads = 1076399 mem = 536883335 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 292806, 36, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 252, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (448.25, 438.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.46, 65.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 877, 1877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4765)
[M::mem_pestat] mean and std.dev: (1063.24, 956.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 290, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3429)
[M::mem_pestat] mean and std.dev: (656.02, 784.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767116 sequences (100000168 bp) in 2.766 CPU sec, 2.950 real sec...
[M::process] read 767058 sequences (100000239 bp) in 1.500 CPU sec, 1.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 292805, 35, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 252, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1341)
[M::mem_pestat] mean and std.dev: (300.29, 253.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 382)
[M::mem_pestat] mean and std.dev: (161.35, 66.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 472)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 395, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (420.97, 435.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 329, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (413.13, 336.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768064 reads in 197.624 CPU sec, 6.329 real sec
sorting block 127, #reads = 1074851 mem = 536883807 peak = 853991424
[M::mem_process_seqs] Processed 767116 reads in 133.929 CPU sec, 4.621 real sec
sorting block 128, #reads = 1078568 mem = 536879063 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 292703, 43, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 381, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (501.22, 416.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 766970 sequences (100000292 bp) in 2.655 CPU sec, 2.847 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.33, 66.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 509, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3082)
[M::mem_pestat] mean and std.dev: (547.38, 512.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (321.89, 250.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766442 sequences (100000033 bp) in 1.570 CPU sec, 1.577 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293061, 31, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 286, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (593.23, 640.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.24, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 562, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (668.93, 555.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 288, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3065)
[M::mem_pestat] mean and std.dev: (526.94, 560.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767116 reads in 208.852 CPU sec, 6.979 real sec
[M::mem_process_seqs] Processed 767058 reads in 135.548 CPU sec, 4.357 real sec
sorting block 129, #reads = 1076822 mem = 536884589 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 292949, 23, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 285, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (518.23, 514.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.35, 66.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 391, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (559.86, 618.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 267, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (325.80, 313.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766816 sequences (100000096 bp) in 2.518 CPU sec, 2.657 real sec...
[M::process] read 767250 sequences (100000134 bp) in 1.500 CPU sec, 1.502 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293534, 41, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 216, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1198)
[M::mem_pestat] mean and std.dev: (283.67, 232.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.52, 66.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 399, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (557.51, 551.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 284, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (431.86, 373.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766970 reads in 193.216 CPU sec, 6.178 real sec
sorting block 130, #reads = 1079499 mem = 536877403 peak = 853991424
[M::mem_process_seqs] Processed 766442 reads in 130.040 CPU sec, 4.495 real sec
sorting block 131, #reads = 1079421 mem = 536881847 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 292934, 42, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 221, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (230.37, 123.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.29, 66.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 650, 2059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5895)
[M::mem_pestat] mean and std.dev: (1057.67, 1255.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 279, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226)
[M::mem_pestat] mean and std.dev: (685.30, 775.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767362 sequences (100000265 bp) in 2.508 CPU sec, 2.692 real sec...
[M::process] read 204960 sequences (26606736 bp) in 0.660 CPU sec, 0.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293373, 32, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 405, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3962)
[M::mem_pestat] mean and std.dev: (706.61, 801.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.80, 65.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 934, 2246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6078)
[M::mem_pestat] mean and std.dev: (1288.40, 1348.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 287, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (428.84, 405.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766816 reads in 195.444 CPU sec, 6.595 real sec
[M::mem_process_seqs] Processed 767250 reads in 131.410 CPU sec, 4.300 real sec
sorting block 132, #reads = 1080076 mem = 536883004 peak = 853991424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293033, 47, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 241, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (454.53, 500.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.99, 66.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 554, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074)
[M::mem_pestat] mean and std.dev: (724.23, 764.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 380, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (516.44, 385.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 78206, 6, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 357, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3456)
[M::mem_pestat] mean and std.dev: (644.60, 755.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.66, 64.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 273, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (354.41, 236.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767362 reads in 133.504 CPU sec, 4.377 real sec
[M::mem_process_seqs] Processed 204960 reads in 55.127 CPU sec, 1.799 real sec
sorting block 133, #reads = 1081002 mem = 536876580 peak = 853991424
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 143557904
overall: 72059662336 mem 28163.360 user 938.470 sys 959.230 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_81F-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 959.259 sec; CPU: 29101.833 sec
sorting block 134, #reads = 672680 mem = 335598262 peak = 853991424
uniq header count 1
merging 135 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 8634771052
output reads: 145563356
bam_mem_sort: 135 calls 101.397 user 2.320 sys 105.161 real
bam_write: 135 calls 84.646 user 6.551 sys 135.880 real
execute: 1 calls 33.215 user 3.588 sys 1003.810 real
merge_files: 1 calls 33.184 user 3.567 sys 43.599 real
parse_chunk: 2155 calls 96.210 user 28.620 sys 140.619 real
read_chunk: 5885 calls 67.179 user 41.191 sys 878.473 real
sort_block: 1 calls 50.607 user 40.259 sys 856.084 real
write_chunk: 3728 calls 32.782 user 3.146 sys 42.363 real
overall: 4054786048 mem 1804.608 user 113.377 sys 1003.826 real
ls: cannot access '*.cram': No such file or directory