This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_5TB-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1840.739 CPU sec, 65.623 real sec
[M::process] read 699920 sequences (100000013 bp) in 1.065 CPU sec, 1.068 real sec...
[M::process] read 699038 sequences (100000216 bp) in 1.583 CPU sec, 1.652 real sec...
[M::process] read 696720 sequences (100000173 bp) in 1.572 CPU sec, 1.576 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 286441, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 268, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2394)
[M::mem_pestat] mean and std.dev: (455.89, 379.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (263.19, 131.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 878, 2141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5179)
[M::mem_pestat] mean and std.dev: (1320.64, 1087.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 276, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (306.72, 199.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695990 sequences (100000026 bp) in 1.249 CPU sec, 1.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285203, 14, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 322, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2460)
[M::mem_pestat] mean and std.dev: (486.36, 481.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (272.76, 135.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 858, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (695.73, 309.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 330, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (344.81, 205.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 286685, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 441, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (464.58, 314.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (265.76, 132.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 754, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3903)
[M::mem_pestat] mean and std.dev: (892.71, 749.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 345, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (546.22, 524.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699920 reads in 275.139 CPU sec, 8.806 real sec
[M::mem_process_seqs] Processed 696720 reads in 187.707 CPU sec, 6.043 real sec
[M::mem_process_seqs] Processed 699038 reads in 205.528 CPU sec, 6.628 real sec
sorting block 0, #reads = 1083929 mem = 536880141 peak = 605540352
[M::process] read 695592 sequences (100000060 bp) in 2.172 CPU sec, 2.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285473, 19, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 248, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (271.68, 141.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (275.75, 138.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 576, 1486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4102)
[M::mem_pestat] mean and std.dev: (733.68, 616.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 315, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (326.06, 144.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695306 sequences (100000223 bp) in 1.615 CPU sec, 1.657 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285080, 18, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 427, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (671.61, 704.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.39, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 681, 3299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9363)
[M::mem_pestat] mean and std.dev: (1752.00, 2045.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 316, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (377.02, 275.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695214 sequences (100000171 bp) in 1.454 CPU sec, 1.466 real sec...
[M::mem_process_seqs] Processed 695990 reads in 174.736 CPU sec, 5.562 real sec
sorting block 1, #reads = 1084537 mem = 536877358 peak = 843042816
[M::mem_process_seqs] Processed 695592 reads in 114.660 CPU sec, 3.812 real sec
sorting block 2, #reads = 1083095 mem = 536878975 peak = 843042816
[M::process] read 694614 sequences (100000280 bp) in 2.034 CPU sec, 2.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284535, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 270, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (365.86, 312.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.00, 136.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 1642, 2936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8376)
[M::mem_pestat] mean and std.dev: (1819.00, 1903.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 306, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (329.03, 176.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693522 sequences (100000134 bp) in 1.420 CPU sec, 1.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 284692, 34, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 227, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (227.12, 139.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (275.03, 136.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 540, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4554)
[M::mem_pestat] mean and std.dev: (531.69, 494.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 427, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (412.77, 249.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284444, 22, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 285, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (256.89, 158.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (277.20, 137.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 742, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (826.90, 827.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 269, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (267.73, 120.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695306 reads in 241.798 CPU sec, 7.925 real sec
[M::mem_process_seqs] Processed 695214 reads in 178.826 CPU sec, 5.755 real sec
[M::mem_process_seqs] Processed 694614 reads in 198.468 CPU sec, 6.401 real sec
sorting block 3, #reads = 1082802 mem = 536879502 peak = 843042816
[M::process] read 692646 sequences (100000173 bp) in 2.372 CPU sec, 2.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284598, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 345, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (438.20, 341.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (279.20, 136.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 4799, 9214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26994)
[M::mem_pestat] mean and std.dev: (4636.69, 4183.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 35884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 358, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (433.82, 333.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1080622 mem = 536879468 peak = 843042816
[M::process] read 694984 sequences (100000050 bp) in 2.062 CPU sec, 2.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283995, 33, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 238, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (234.51, 82.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (283.80, 139.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 697, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4486)
[M::mem_pestat] mean and std.dev: (910.69, 716.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5852)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 428, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (427.36, 311.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693522 reads in 173.126 CPU sec, 5.524 real sec
[M::mem_process_seqs] Processed 692646 reads in 112.981 CPU sec, 3.565 real sec
[M::process] read 699690 sequences (100000138 bp) in 1.802 CPU sec, 1.859 real sec...
sorting block 5, #reads = 1080983 mem = 536879633 peak = 843042816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284913, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 408, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1965)
[M::mem_pestat] mean and std.dev: (510.10, 445.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (277.74, 137.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 879, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (602.54, 435.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 295, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (306.39, 153.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698608 sequences (100000115 bp) in 2.598 CPU sec, 2.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 286398, 16, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 301, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (379.54, 300.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (265.80, 133.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (804, 1356, 7746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21630)
[M::mem_pestat] mean and std.dev: (3118.31, 3197.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 282, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (284.64, 135.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694984 reads in 171.054 CPU sec, 5.465 real sec
[M::process] read 697260 sequences (100000145 bp) in 2.083 CPU sec, 2.090 real sec...
[M::mem_process_seqs] Processed 699690 reads in 109.562 CPU sec, 3.475 real sec
sorting block 6, #reads = 1080665 mem = 536882456 peak = 843042816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 286233, 20, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 282, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (331.45, 284.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.00, 135.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 531, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (411.25, 191.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 275, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (272.94, 148.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696172 sequences (100000004 bp) in 2.584 CPU sec, 2.705 real sec...
[M::process] read 695756 sequences (100000075 bp) in 1.769 CPU sec, 1.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 285414, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 414, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (461.69, 301.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (273.76, 137.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1235, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4374)
[M::mem_pestat] mean and std.dev: (1236.38, 1088.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 297, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (264.18, 137.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698608 reads in 168.630 CPU sec, 5.364 real sec
sorting block 7, #reads = 1086645 mem = 536880740 peak = 843042816
[M::mem_process_seqs] Processed 697260 reads in 110.390 CPU sec, 3.502 real sec
sorting block 8, #reads = 1085166 mem = 536878728 peak = 843468800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284897, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 301, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (493.67, 524.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.46, 139.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (595, 836, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4756)
[M::mem_pestat] mean and std.dev: (1546.26, 1731.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 244, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (337.66, 320.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695586 sequences (100000100 bp) in 2.371 CPU sec, 2.489 real sec...
[M::process] read 695706 sequences (100000058 bp) in 1.749 CPU sec, 1.753 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285128, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 235, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (305.41, 188.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (277.29, 139.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 1126, 2887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8331)
[M::mem_pestat] mean and std.dev: (1386.52, 1202.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 261, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1341)
[M::mem_pestat] mean and std.dev: (346.51, 224.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696172 reads in 172.082 CPU sec, 5.588 real sec
[M::mem_process_seqs] Processed 695756 reads in 108.203 CPU sec, 3.454 real sec
sorting block 9, #reads = 1082556 mem = 536880569 peak = 843468800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285026, 20, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 423, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (377.84, 200.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.31, 136.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 196, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (331.29, 406.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 340, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (411.52, 262.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694686 sequences (100000049 bp) in 2.618 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284699, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 248, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (276.20, 138.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.21, 135.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (619, 1136, 4954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13624)
[M::mem_pestat] mean and std.dev: (2108.68, 1959.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 318, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (378.28, 231.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693992 sequences (100000018 bp) in 1.810 CPU sec, 1.816 real sec...
[M::mem_process_seqs] Processed 695586 reads in 173.772 CPU sec, 5.610 real sec
[M::mem_process_seqs] Processed 695706 reads in 110.775 CPU sec, 3.508 real sec
sorting block 10, #reads = 1082646 mem = 536878311 peak = 843468800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284691, 20, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 342, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (340.59, 207.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.50, 135.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 509, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (634.58, 626.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 392, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3440)
[M::mem_pestat] mean and std.dev: (521.36, 458.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693480 sequences (100000016 bp) in 2.433 CPU sec, 2.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284490, 26, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 236, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (290.02, 200.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (278.90, 137.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 631, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (636.35, 481.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 335, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (473.79, 452.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698804 sequences (100000035 bp) in 1.839 CPU sec, 1.845 real sec...
[M::mem_process_seqs] Processed 694686 reads in 165.901 CPU sec, 5.275 real sec
[M::mem_process_seqs] Processed 693992 reads in 106.973 CPU sec, 3.389 real sec
sorting block 11, #reads = 1082036 mem = 536879178 peak = 843468800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284546, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 743, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3227)
[M::mem_pestat] mean and std.dev: (870.30, 786.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (280.58, 138.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 1232, 3061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8045)
[M::mem_pestat] mean and std.dev: (1609.00, 1281.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 256, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (247.45, 137.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700608 sequences (100000074 bp) in 2.711 CPU sec, 2.863 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 286685, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 322, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (321.54, 200.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.11, 135.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 1610, 2556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6692)
[M::mem_pestat] mean and std.dev: (1367.10, 1267.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 268, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (314.28, 209.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698822 sequences (100000038 bp) in 1.690 CPU sec, 1.693 real sec...
[M::mem_process_seqs] Processed 693480 reads in 170.019 CPU sec, 5.476 real sec
sorting block 12, #reads = 1080694 mem = 536878136 peak = 843468800
[M::mem_process_seqs] Processed 698804 reads in 108.380 CPU sec, 3.430 real sec
sorting block 13, #reads = 1082627 mem = 536879743 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287215, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 371, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (465.42, 350.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (263.43, 132.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 1011, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (763.08, 400.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 319, 1749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4859)
[M::mem_pestat] mean and std.dev: (785.72, 905.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696988 sequences (100000276 bp) in 2.932 CPU sec, 3.057 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285769, 20, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 249, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (286.47, 194.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (267.43, 133.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 1114, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (1019.84, 921.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 329, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (372.88, 223.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696306 sequences (100000032 bp) in 1.880 CPU sec, 1.879 real sec...
[M::mem_process_seqs] Processed 700608 reads in 173.455 CPU sec, 5.509 real sec
[M::mem_process_seqs] Processed 698822 reads in 114.110 CPU sec, 3.610 real sec
sorting block 14, #reads = 1087024 mem = 536879125 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286182, 20, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 379, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (410.22, 298.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (272.53, 134.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 1931, 2725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7279)
[M::mem_pestat] mean and std.dev: (1902.15, 1574.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (267.71, 183.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696116 sequences (100000210 bp) in 2.510 CPU sec, 2.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285203, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 250, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (268.09, 192.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.02, 136.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 1117, 2050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5512)
[M::mem_pestat] mean and std.dev: (1023.00, 718.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7243)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 308, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (386.87, 252.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695314 sequences (100000128 bp) in 2.020 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 696988 reads in 177.992 CPU sec, 5.700 real sec
[M::mem_process_seqs] Processed 696306 reads in 114.352 CPU sec, 3.625 real sec
sorting block 15, #reads = 1084654 mem = 536879772 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 285594, 10, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 311, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (489.55, 453.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3508)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.46, 136.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 1370, 6575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19137)
[M::mem_pestat] mean and std.dev: (2846.90, 3380.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 408, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (465.21, 280.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694830 sequences (100000060 bp) in 2.680 CPU sec, 2.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284364, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 432, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (342.48, 176.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (274.17, 135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 856, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4576)
[M::mem_pestat] mean and std.dev: (884.33, 654.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 363, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (469.21, 329.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694770 sequences (100000126 bp) in 1.660 CPU sec, 1.663 real sec...
[M::mem_process_seqs] Processed 696116 reads in 166.304 CPU sec, 5.298 real sec
sorting block 16, #reads = 1083944 mem = 536878840 peak = 902311936
[M::mem_process_seqs] Processed 695314 reads in 117.086 CPU sec, 3.730 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284785, 14, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 374, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1341)
[M::mem_pestat] mean and std.dev: (416.89, 290.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.10, 135.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 715, 2383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6821)
[M::mem_pestat] mean and std.dev: (1337.36, 1446.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 332, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (385.53, 260.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1082193 mem = 536877967 peak = 902311936
[M::process] read 694304 sequences (100000157 bp) in 2.545 CPU sec, 2.657 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284306, 17, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (282.00, 152.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (275.30, 135.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 483, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3988)
[M::mem_pestat] mean and std.dev: (586.07, 491.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 292, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (290.02, 176.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695182 sequences (100000244 bp) in 1.750 CPU sec, 1.749 real sec...
[M::mem_process_seqs] Processed 694830 reads in 165.455 CPU sec, 5.252 real sec
[M::mem_process_seqs] Processed 694770 reads in 109.071 CPU sec, 3.446 real sec
sorting block 18, #reads = 1081761 mem = 536881148 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284582, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 256, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (263.18, 148.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.05, 137.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 1001, 2477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7061)
[M::mem_pestat] mean and std.dev: (1126.00, 1140.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 368, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (473.60, 391.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700588 sequences (100000280 bp) in 2.161 CPU sec, 2.298 real sec...
[M::process] read 699430 sequences (100000041 bp) in 1.393 CPU sec, 1.395 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285056, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 218, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (475.12, 457.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.80, 137.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (670, 995, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4588)
[M::mem_pestat] mean and std.dev: (908.09, 620.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 319, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (373.40, 265.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694304 reads in 176.312 CPU sec, 5.856 real sec
[M::mem_process_seqs] Processed 695182 reads in 114.094 CPU sec, 3.650 real sec
sorting block 19, #reads = 1079283 mem = 536880658 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286555, 21, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 254, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (264.43, 118.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (263.12, 131.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (633, 1270, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4584)
[M::mem_pestat] mean and std.dev: (1377.00, 897.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 258, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (262.02, 113.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698002 sequences (100000089 bp) in 2.516 CPU sec, 2.639 real sec...
[M::process] read 696808 sequences (100000032 bp) in 1.400 CPU sec, 1.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 286836, 24, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 288, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (316.75, 176.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (267.22, 133.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 1537, 2279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6227)
[M::mem_pestat] mean and std.dev: (1785.12, 1715.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 367, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662)
[M::mem_pestat] mean and std.dev: (759.58, 994.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700588 reads in 166.868 CPU sec, 5.308 real sec
sorting block 20, #reads = 1081150 mem = 536882185 peak = 902311936
[M::mem_process_seqs] Processed 699430 reads in 109.432 CPU sec, 3.473 real sec
sorting block 21, #reads = 1086742 mem = 536887598 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285744, 17, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 249, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.56, 90.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (270.62, 135.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (638, 950, 2425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5999)
[M::mem_pestat] mean and std.dev: (1404.65, 1057.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 382, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (375.37, 199.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696412 sequences (100000027 bp) in 2.418 CPU sec, 2.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284781, 33, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 423, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4716)
[M::mem_pestat] mean and std.dev: (942.00, 1077.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (273.68, 136.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 798, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4158)
[M::mem_pestat] mean and std.dev: (870.19, 620.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 313, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (424.81, 351.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2644)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696730 sequences (100000191 bp) in 1.890 CPU sec, 1.893 real sec...
[M::mem_process_seqs] Processed 698002 reads in 160.264 CPU sec, 5.072 real sec
[M::mem_process_seqs] Processed 696808 reads in 104.757 CPU sec, 3.313 real sec
sorting block 22, #reads = 1084050 mem = 536879632 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 285265, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 286, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (473.12, 574.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.92, 136.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 543, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (690.11, 580.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 255, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (315.83, 224.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695896 sequences (100000195 bp) in 2.621 CPU sec, 2.724 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285052, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 383, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (547.51, 486.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (270.60, 134.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 958, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (758.93, 400.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 352, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (383.56, 228.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695094 sequences (100000069 bp) in 1.810 CPU sec, 1.809 real sec...
[M::mem_process_seqs] Processed 696412 reads in 163.991 CPU sec, 5.198 real sec
[M::mem_process_seqs] Processed 696730 reads in 107.485 CPU sec, 3.393 real sec
sorting block 23, #reads = 1084465 mem = 536878494 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284977, 20, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 323, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (292.07, 177.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (271.24, 133.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 940, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4146)
[M::mem_pestat] mean and std.dev: (931.55, 831.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 298, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (331.11, 198.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694418 sequences (100000068 bp) in 2.618 CPU sec, 2.747 real sec...
[M::process] read 693886 sequences (100000128 bp) in 1.674 CPU sec, 1.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284717, 32, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 314, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (371.58, 242.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (271.94, 132.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 863, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4657)
[M::mem_pestat] mean and std.dev: (1188.61, 955.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 297, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (313.48, 182.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695896 reads in 167.842 CPU sec, 5.337 real sec
[M::mem_process_seqs] Processed 695094 reads in 110.741 CPU sec, 3.523 real sec
sorting block 24, #reads = 1081216 mem = 536878644 peak = 902311936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284241, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 238, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (370.89, 329.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (273.04, 132.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 595, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4224)
[M::mem_pestat] mean and std.dev: (936.59, 807.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (369.90, 343.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700518 sequences (100000248 bp) in 2.572 CPU sec, 2.680 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 284125, 39, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 306, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (373.85, 274.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 254, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (277.79, 136.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 1127, 2449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6429)
[M::mem_pestat] mean and std.dev: (1670.63, 1783.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 308, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1705)
[M::mem_pestat] mean and std.dev: (344.83, 298.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702166 sequences (100000082 bp) in 1.890 CPU sec, 1.885 real sec...
[M::mem_process_seqs] Processed 694418 reads in 169.826 CPU sec, 5.393 real sec
sorting block 25, #reads = 1081879 mem = 536879301 peak = 902311936
[M::mem_process_seqs] Processed 693886 reads in 118.923 CPU sec, 3.781 real sec
sorting block 26, #reads = 1079612 mem = 536878761 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 286668, 21, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 176, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (478.24, 514.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.95, 131.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 862, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (1017.76, 641.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 372, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (381.87, 250.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699792 sequences (100000199 bp) in 2.180 CPU sec, 2.271 real sec...
[M::process] read 698196 sequences (100000124 bp) in 1.977 CPU sec, 1.980 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 287671, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 211, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (280.77, 198.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (257.68, 131.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 294, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4470)
[M::mem_pestat] mean and std.dev: (577.32, 682.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 240, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (297.20, 207.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700518 reads in 183.697 CPU sec, 5.850 real sec
[M::mem_process_seqs] Processed 702166 reads in 121.850 CPU sec, 3.884 real sec
sorting block 27, #reads = 1081980 mem = 536884687 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 286707, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (254.56, 120.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (265.13, 134.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 623, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (537.26, 361.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 340, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (577.10, 657.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697510 sequences (100000002 bp) in 2.660 CPU sec, 2.786 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286155, 19, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 325, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1565)
[M::mem_pestat] mean and std.dev: (365.95, 287.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.82, 136.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 1647, 3922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11068)
[M::mem_pestat] mean and std.dev: (2252.21, 2574.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14641)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 388, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (463.49, 469.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3940)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696262 sequences (100000188 bp) in 1.890 CPU sec, 1.896 real sec...
[M::mem_process_seqs] Processed 699792 reads in 178.359 CPU sec, 5.689 real sec
[M::mem_process_seqs] Processed 698196 reads in 118.650 CPU sec, 3.764 real sec
sorting block 28, #reads = 1084685 mem = 536883436 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 286380, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 315, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (259.05, 102.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.59, 136.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 806, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4106)
[M::mem_pestat] mean and std.dev: (1027.24, 976.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 271, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (343.48, 233.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695984 sequences (100000037 bp) in 2.657 CPU sec, 2.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285324, 25, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 512, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (448.19, 273.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (273.97, 137.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 877, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4378)
[M::mem_pestat] mean and std.dev: (1175.28, 933.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 231, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (313.16, 219.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695368 sequences (100000137 bp) in 1.926 CPU sec, 1.934 real sec...
[M::mem_process_seqs] Processed 697510 reads in 187.502 CPU sec, 6.005 real sec
sorting block 29, #reads = 1082891 mem = 536878489 peak = 929808384
[M::mem_process_seqs] Processed 696262 reads in 125.209 CPU sec, 3.987 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284908, 20, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 310, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1608)
[M::mem_pestat] mean and std.dev: (463.98, 425.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.52, 136.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 801, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (702.95, 702.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 287, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (270.43, 104.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1081823 mem = 536878856 peak = 929808384
[M::process] read 695180 sequences (100000048 bp) in 2.949 CPU sec, 3.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284685, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 237, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (255.86, 154.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 694614 sequences (100000235 bp) in 1.874 CPU sec, 1.881 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.39, 136.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 924, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (853.06, 715.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 375, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (796.51, 893.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695984 reads in 192.062 CPU sec, 6.119 real sec
[M::mem_process_seqs] Processed 695368 reads in 128.350 CPU sec, 4.071 real sec
sorting block 31, #reads = 1078615 mem = 536883970 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285407, 13, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 349, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (495.81, 578.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.27, 136.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 668, 2549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6801)
[M::mem_pestat] mean and std.dev: (1160.08, 1029.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 317, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (303.27, 180.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702154 sequences (100000215 bp) in 2.626 CPU sec, 2.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285191, 23, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 265, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (272.02, 153.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (276.76, 137.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 528, 3345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9365)
[M::mem_pestat] mean and std.dev: (1934.95, 2321.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 335, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (387.41, 261.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705744 sequences (100000298 bp) in 1.971 CPU sec, 1.973 real sec...
[M::mem_process_seqs] Processed 695180 reads in 188.424 CPU sec, 6.020 real sec
[M::mem_process_seqs] Processed 694614 reads in 132.026 CPU sec, 4.211 real sec
sorting block 32, #reads = 1079491 mem = 536880544 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 287809, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 290, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (268.88, 114.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.57, 128.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (560, 629, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (483.80, 311.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 318, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (633.71, 771.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702870 sequences (100000108 bp) in 2.676 CPU sec, 2.817 real sec...
[M::process] read 701084 sequences (100000088 bp) in 1.924 CPU sec, 1.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289047, 15, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 258, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (291.47, 170.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.52, 122.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (595, 812, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (770.57, 453.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 329, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (328.11, 191.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702154 reads in 193.586 CPU sec, 6.177 real sec
sorting block 33, #reads = 1079112 mem = 536878562 peak = 929808384
[M::mem_process_seqs] Processed 705744 reads in 128.584 CPU sec, 4.073 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 288160, 3, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 448, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (507.53, 405.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (254.61, 127.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 289, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (558.89, 522.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 699742 sequences (100000181 bp) in 2.601 CPU sec, 2.708 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 287552, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 173, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (238.61, 161.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 698192 sequences (100000137 bp) in 1.944 CPU sec, 1.946 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (260.24, 130.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 978, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3693)
[M::mem_pestat] mean and std.dev: (798.00, 677.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 326, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (545.08, 512.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702870 reads in 185.341 CPU sec, 5.904 real sec
sorting block 34, #reads = 1082617 mem = 536879064 peak = 929808384
[M::mem_process_seqs] Processed 701084 reads in 119.750 CPU sec, 3.826 real sec
sorting block 35, #reads = 1082090 mem = 536878652 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 286607, 11, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 294, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (328.93, 231.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (263.55, 132.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 460, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (300, 595)
[M::mem_pestat] mean and std.dev: (430.10, 43.17)
[M::mem_pestat] low and high boundaries for proper pairs: (241, 654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (253.78, 116.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696858 sequences (100000130 bp) in 2.630 CPU sec, 2.725 real sec...
[M::process] read 696172 sequences (100000038 bp) in 1.853 CPU sec, 1.856 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 286309, 13, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 297, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (339.79, 279.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.87, 135.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 1692, 2686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6814)
[M::mem_pestat] mean and std.dev: (1689.69, 1074.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 301, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (472.30, 441.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699742 reads in 193.395 CPU sec, 6.189 real sec
[M::mem_process_seqs] Processed 698192 reads in 128.115 CPU sec, 4.086 real sec
sorting block 36, #reads = 1081872 mem = 536878568 peak = 929808384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 285380, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 437, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (509.10, 433.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (271.08, 135.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 680, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5266)
[M::mem_pestat] mean and std.dev: (796.88, 814.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 367, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (361.25, 233.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694774 sequences (100000221 bp) in 2.718 CPU sec, 2.904 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 285403, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 223, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (244.71, 141.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.41, 136.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (545, 867, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (764.00, 509.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 324, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (413.90, 321.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694714 sequences (100000105 bp) in 2.073 CPU sec, 2.081 real sec...
[M::mem_process_seqs] Processed 696858 reads in 199.101 CPU sec, 6.365 real sec
sorting block 37, #reads = 1079393 mem = 536877890 peak = 948215808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284792, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 376, 1613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4421)
[M::mem_pestat] mean and std.dev: (790.98, 731.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (276.30, 136.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 791, 1582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4206)
[M::mem_pestat] mean and std.dev: (679.21, 506.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 245, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (273.33, 145.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704756 sequences (100000040 bp) in 2.280 CPU sec, 2.294 real sec...
[M::mem_process_seqs] Processed 694774 reads in 108.717 CPU sec, 3.445 real sec
[M::mem_process_seqs] Processed 696172 reads in 283.721 CPU sec, 9.052 real sec
sorting block 38, #reads = 1079610 mem = 536878429 peak = 948215808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284631, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 277, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (433.82, 393.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (276.75, 137.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (499, 1166, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4381)
[M::mem_pestat] mean and std.dev: (1065.44, 755.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 320, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (363.91, 249.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702348 sequences (100000268 bp) in 2.894 CPU sec, 3.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 288465, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 214, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1536)
[M::mem_pestat] mean and std.dev: (351.67, 289.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.93, 124.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (461, 2312, 4090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11348)
[M::mem_pestat] mean and std.dev: (1972.08, 1612.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 334, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (382.97, 204.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694714 reads in 217.228 CPU sec, 6.918 real sec
[M::process] read 700268 sequences (100000218 bp) in 1.927 CPU sec, 1.957 real sec...
[M::mem_process_seqs] Processed 704756 reads in 129.650 CPU sec, 4.102 real sec
sorting block 39, #reads = 1079491 mem = 536880033 peak = 948215808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 287839, 17, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 261, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (392.90, 310.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.77, 128.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 497, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (524.53, 558.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (249.70, 105.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699346 sequences (100000035 bp) in 2.987 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 286887, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 263, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (476.31, 447.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (262.12, 130.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 1101, 2769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7743)
[M::mem_pestat] mean and std.dev: (1327.83, 1192.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 342, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (638.02, 696.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698884 sequences (100000117 bp) in 1.711 CPU sec, 1.720 real sec...
[M::mem_process_seqs] Processed 702348 reads in 188.120 CPU sec, 6.014 real sec
sorting block 40, #reads = 1082523 mem = 536883920 peak = 948215808
[M::mem_process_seqs] Processed 700268 reads in 122.293 CPU sec, 3.886 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 287030, 2, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 335, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (470.85, 397.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 41, #reads = 1086284 mem = 536877329 peak = 968859648
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (265.22, 132.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 320, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (423.48, 374.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 698492 sequences (100000073 bp) in 2.776 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 286702, 14, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 311, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (354.34, 281.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (265.89, 131.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 869, 2695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7377)
[M::mem_pestat] mean and std.dev: (1698.86, 2016.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 294, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (274.96, 154.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697072 sequences (100000075 bp) in 1.955 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 699346 reads in 190.463 CPU sec, 6.093 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286345, 15, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 233, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (347.82, 298.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (265.40, 131.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 475, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2632)
[M::mem_pestat] mean and std.dev: (602.14, 454.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 273, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (357.66, 246.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696638 sequences (100000034 bp) in 2.407 CPU sec, 2.424 real sec...
[M::mem_process_seqs] Processed 698492 reads in 111.176 CPU sec, 3.737 real sec
sorting block 42, #reads = 1083962 mem = 536881270 peak = 968859648
[M::mem_process_seqs] Processed 698884 reads in 275.227 CPU sec, 9.000 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 285762, 19, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 374, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (686.43, 616.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.59, 135.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 905, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4008)
[M::mem_pestat] mean and std.dev: (1026.11, 907.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 286, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (420.21, 384.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1084365 mem = 536879105 peak = 968859648
[M::process] read 695708 sequences (100000045 bp) in 2.991 CPU sec, 3.505 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 285559, 30, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 410, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (656.98, 701.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (270.73, 134.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 941, 2661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7587)
[M::mem_pestat] mean and std.dev: (1349.69, 1430.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 345, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (419.74, 333.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697072 reads in 219.089 CPU sec, 7.237 real sec
[M::process] read 695536 sequences (100000161 bp) in 2.352 CPU sec, 2.432 real sec...
[M::mem_process_seqs] Processed 696638 reads in 134.619 CPU sec, 4.582 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285143, 11, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 335, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (327.39, 154.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.88, 136.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 996, 2577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6925)
[M::mem_pestat] mean and std.dev: (1673.18, 1544.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 245, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (312.37, 238.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1081073 mem = 536883204 peak = 968859648
[M::process] read 708266 sequences (100000239 bp) in 2.659 CPU sec, 3.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285065, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 306, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1635)
[M::mem_pestat] mean and std.dev: (418.92, 352.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.14, 136.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 554, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (790.88, 778.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 292, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (545.85, 489.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695708 reads in 210.782 CPU sec, 7.202 real sec
[M::process] read 705568 sequences (100000188 bp) in 2.292 CPU sec, 2.532 real sec...
[M::mem_process_seqs] Processed 695536 reads in 146.885 CPU sec, 4.765 real sec
sorting block 45, #reads = 1078523 mem = 536878888 peak = 968859648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289722, 18, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 204, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (255.81, 175.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (240.23, 119.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 768, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5071)
[M::mem_pestat] mean and std.dev: (906.82, 875.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 379, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (670.48, 579.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703028 sequences (100000096 bp) in 3.033 CPU sec, 3.422 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 288765, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 257, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (370.52, 354.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.96, 123.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 902, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (787.29, 487.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 288, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (342.80, 213.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700988 sequences (100000080 bp) in 2.166 CPU sec, 2.455 real sec...
[M::mem_process_seqs] Processed 708266 reads in 217.879 CPU sec, 7.226 real sec
[M::mem_process_seqs] Processed 705568 reads in 144.800 CPU sec, 4.857 real sec
sorting block 46, #reads = 1076534 mem = 536887038 peak = 968859648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 288262, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 228, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (283.29, 169.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (254.84, 127.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 1404, 2127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5521)
[M::mem_pestat] mean and std.dev: (1336.06, 1179.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 306, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1816)
[M::mem_pestat] mean and std.dev: (416.11, 308.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700742 sequences (100000301 bp) in 2.562 CPU sec, 3.047 real sec...
sorting block 47, #reads = 1082667 mem = 536877786 peak = 972996608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287152, 16, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 356, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (466.32, 316.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (260.63, 130.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (629, 1132, 4672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12758)
[M::mem_pestat] mean and std.dev: (1905.31, 1829.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 323, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1094)
[M::mem_pestat] mean and std.dev: (320.04, 194.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703028 reads in 210.234 CPU sec, 7.530 real sec
[M::process] read 697850 sequences (100000103 bp) in 2.232 CPU sec, 2.725 real sec...
[M::mem_process_seqs] Processed 700988 reads in 141.289 CPU sec, 5.167 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286633, 13, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 384, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254)
[M::mem_pestat] mean and std.dev: (507.26, 448.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.19, 131.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 526, 2611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7331)
[M::mem_pestat] mean and std.dev: (978.08, 1337.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 324, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (341.80, 162.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1082072 mem = 536880110 peak = 972996608
[M::process] read 695994 sequences (100000065 bp) in 2.786 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285951, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 259, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (588.67, 679.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.38, 131.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 1107, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3720)
[M::mem_pestat] mean and std.dev: (1027.70, 766.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 277, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (347.30, 230.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700742 reads in 208.982 CPU sec, 7.053 real sec
[M::process] read 695410 sequences (100000151 bp) in 2.069 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 697850 reads in 140.962 CPU sec, 4.763 real sec
sorting block 49, #reads = 1080033 mem = 536876881 peak = 972996608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284717, 22, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 287, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (284.39, 174.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (270.15, 132.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 532, 1857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5307)
[M::mem_pestat] mean and std.dev: (932.95, 1239.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 307, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (391.95, 300.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694230 sequences (100000127 bp) in 2.688 CPU sec, 3.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285118, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 264, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (388.52, 401.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (269.99, 131.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 1119, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (894.86, 747.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 344, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (664.56, 595.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 498728 sequences (71836125 bp) in 1.776 CPU sec, 1.834 real sec...
[M::mem_process_seqs] Processed 695994 reads in 206.067 CPU sec, 7.129 real sec
[M::mem_process_seqs] Processed 695410 reads in 136.134 CPU sec, 4.503 real sec
sorting block 50, #reads = 1077667 mem = 536876843 peak = 972996608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284404, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 276, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (287.31, 169.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (276.15, 135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 641, 2672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7440)
[M::mem_pestat] mean and std.dev: (874.45, 934.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 407, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (521.58, 449.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 204685, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 598, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (714.21, 605.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.32, 138.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 653, 2677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7503)
[M::mem_pestat] mean and std.dev: (1021.29, 995.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 329, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (292.24, 148.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694230 reads in 168.806 CPU sec, 5.871 real sec
sorting block 51, #reads = 1079327 mem = 536878543 peak = 1041223680
[M::mem_process_seqs] Processed 498728 reads in 97.359 CPU sec, 3.506 real sec
sorting block 52, #reads = 1080159 mem = 536884569 peak = 1041223680
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 57001536
overall: 69982613504 mem 9768.520 user 330.588 sys 346.350 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_5TB-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0002.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0002.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 346.384 sec; CPU: 10099.111 sec
sorting block 53, #reads = 27367 mem = 13716046 peak = 1041223680
uniq header count 1
merging 54 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3326729204
output reads: 57373202
bam_mem_sort: 54 calls 31.101 user 0.796 sys 32.259 real
bam_write: 54 calls 19.299 user 1.202 sys 29.214 real
execute: 1 calls 18.134 user 2.380 sys 370.511 real
merge_files: 1 calls 18.109 user 2.356 sys 24.084 real
parse_chunk: 849 calls 35.619 user 9.565 sys 48.973 real
read_chunk: 2295 calls 21.049 user 16.171 sys 282.446 real
sort_block: 1 calls 13.498 user 15.330 sys 270.899 real
write_chunk: 1444 calls 17.475 user 2.088 sys 22.765 real
overall: 2700562432 mem 852.252 user 41.845 sys 370.532 real
ls: cannot access '*.cram': No such file or directory