cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1655.537 CPU sec, 59.253 real sec
[M::process] read 729066 sequences (100000039 bp) in 1.518 CPU sec, 1.528 real sec...
[M::process] read 728614 sequences (100000038 bp) in 1.732 CPU sec, 1.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 288095, 81, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 541, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (746.46, 652.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.25, 88.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 477, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (638.66, 684.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (317, 736, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3815)
[M::mem_pestat] mean and std.dev: (888.39, 743.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728660 sequences (100000234 bp) in 1.794 CPU sec, 1.792 real sec...
[M::process] read 727862 sequences (100000162 bp) in 1.776 CPU sec, 1.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287964, 67, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 334, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (627.19, 649.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.10, 89.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 1125, 3300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9130)
[M::mem_pestat] mean and std.dev: (2098.61, 2321.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 519, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (655.84, 503.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729066 reads in 209.679 CPU sec, 6.654 real sec
[M::mem_process_seqs] Processed 728614 reads in 140.379 CPU sec, 4.475 real sec
sorting block 0, #reads = 1080240 mem = 536878705 peak = 607047680
[M::process] read 727152 sequences (100000103 bp) in 2.389 CPU sec, 2.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 288306, 74, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 465, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (672.54, 546.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.55, 89.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 822, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4632)
[M::mem_pestat] mean and std.dev: (967.07, 953.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 530, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (621.14, 504.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726472 sequences (100000023 bp) in 1.779 CPU sec, 1.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 288350, 70, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 331, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2329)
[M::mem_pestat] mean and std.dev: (499.85, 473.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.23, 90.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 446, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (613.08, 728.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 363, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (772.79, 856.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728660 reads in 213.842 CPU sec, 6.804 real sec
sorting block 1, #reads = 1078899 mem = 536878888 peak = 764334080
[M::mem_process_seqs] Processed 727862 reads in 243.929 CPU sec, 7.781 real sec
[M::process] read 726076 sequences (100000140 bp) in 2.894 CPU sec, 2.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287896, 56, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 560, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938)
[M::mem_pestat] mean and std.dev: (636.47, 499.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.84, 92.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 528, 1801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4927)
[M::mem_pestat] mean and std.dev: (838.77, 965.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 299, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (395.90, 302.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725702 sequences (100000125 bp) in 1.790 CPU sec, 1.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288245, 67, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 462, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (705.43, 589.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.50, 91.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 400, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (434.90, 411.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 535, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (567.62, 450.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3274)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726472 reads in 214.959 CPU sec, 6.828 real sec
sorting block 2, #reads = 1078494 mem = 536880576 peak = 764334080
[M::mem_process_seqs] Processed 727152 reads in 245.932 CPU sec, 7.845 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287792, 65, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 396, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (572.88, 498.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.82, 93.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 604, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (823.34, 700.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 418, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (613.64, 591.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 3, #reads = 1080849 mem = 536881896 peak = 800477184
[M::process] read 725290 sequences (100000231 bp) in 3.287 CPU sec, 3.462 real sec...
[M::process] read 725144 sequences (100000129 bp) in 2.079 CPU sec, 2.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286729, 62, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 394, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (392.37, 281.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.84, 93.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 734, 1436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (904.64, 868.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 727, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (756.62, 620.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726076 reads in 213.629 CPU sec, 6.787 real sec
[M::mem_process_seqs] Processed 725702 reads in 150.372 CPU sec, 5.133 real sec
sorting block 4, #reads = 1078453 mem = 536881017 peak = 800477184
[M::process] read 724602 sequences (100000233 bp) in 2.754 CPU sec, 2.888 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286911, 84, 127)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 466, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (594.97, 499.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (201.08, 92.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 802, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5310)
[M::mem_pestat] mean and std.dev: (869.72, 914.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7021)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 451, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1997)
[M::mem_pestat] mean and std.dev: (530.04, 399.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724700 sequences (100000124 bp) in 2.102 CPU sec, 2.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286797, 60, 135)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 432, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (635.76, 670.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.93, 92.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 306, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (442.33, 462.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 438, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4580)
[M::mem_pestat] mean and std.dev: (857.00, 909.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725290 reads in 219.617 CPU sec, 7.328 real sec
sorting block 5, #reads = 1078623 mem = 536881103 peak = 800477184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286945, 64, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 586, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4262)
[M::mem_pestat] mean and std.dev: (1033.04, 1123.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.26, 92.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 687, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (742.93, 627.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 418, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (630.75, 574.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724916 sequences (100000145 bp) in 2.195 CPU sec, 2.198 real sec...
[M::mem_process_seqs] Processed 725144 reads in 247.653 CPU sec, 7.877 real sec
[M::mem_process_seqs] Processed 724602 reads in 285.011 CPU sec, 9.108 real sec
sorting block 6, #reads = 1078113 mem = 536879445 peak = 800477184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286735, 76, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 426, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733)
[M::mem_pestat] mean and std.dev: (649.74, 602.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.85, 92.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 575, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (660.52, 548.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3952)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 445, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (633.65, 577.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724790 sequences (100000063 bp) in 3.286 CPU sec, 3.498 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286371, 69, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 406, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (517.81, 402.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.62, 91.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 578, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (954.00, 984.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 532, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (684.30, 569.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724700 reads in 215.729 CPU sec, 6.852 real sec
[M::process] read 724510 sequences (100000006 bp) in 2.610 CPU sec, 2.616 real sec...
[M::mem_process_seqs] Processed 724916 reads in 161.875 CPU sec, 5.154 real sec
sorting block 7, #reads = 1077795 mem = 536881625 peak = 800477184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 286302, 80, 127)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 370, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (597.49, 570.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.75, 92.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 548, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3303)
[M::mem_pestat] mean and std.dev: (649.87, 639.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 474, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3113)
[M::mem_pestat] mean and std.dev: (680.75, 639.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723656 sequences (100000027 bp) in 3.094 CPU sec, 3.320 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 286497, 63, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 310, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (386.36, 284.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.01, 92.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 549, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4115)
[M::mem_pestat] mean and std.dev: (820.22, 781.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 376, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (478.57, 404.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723484 sequences (100000155 bp) in 2.300 CPU sec, 2.302 real sec...
[M::mem_process_seqs] Processed 724790 reads in 223.488 CPU sec, 7.121 real sec
sorting block 8, #reads = 1076527 mem = 536880041 peak = 800477184
[M::mem_process_seqs] Processed 724510 reads in 158.129 CPU sec, 5.392 real sec
sorting block 9, #reads = 1077993 mem = 536879857 peak = 825614336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286260, 78, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 458, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2571)
[M::mem_pestat] mean and std.dev: (609.79, 557.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.19, 93.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 324, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (464.97, 563.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 510, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (692.55, 510.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723074 sequences (100000044 bp) in 3.438 CPU sec, 3.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287112, 83, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 372, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (451.39, 389.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (203.15, 93.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 582, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (625.16, 506.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 501, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3113)
[M::mem_pestat] mean and std.dev: (609.16, 522.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722742 sequences (100000109 bp) in 2.169 CPU sec, 2.169 real sec...
[M::mem_process_seqs] Processed 723656 reads in 224.609 CPU sec, 7.493 real sec
[M::mem_process_seqs] Processed 723484 reads in 151.605 CPU sec, 4.979 real sec
sorting block 10, #reads = 1076179 mem = 536879730 peak = 825614336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 285578, 76, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 533, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (716.64, 650.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.16, 94.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 806, 1683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4111)
[M::mem_pestat] mean and std.dev: (1027.68, 940.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 488, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (638.76, 529.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722102 sequences (100000162 bp) in 2.968 CPU sec, 3.115 real sec...
[M::process] read 722366 sequences (100000021 bp) in 2.240 CPU sec, 2.246 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 286546, 74, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 379, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (463.73, 377.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.56, 94.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 626, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (645.60, 507.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 516, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4049)
[M::mem_pestat] mean and std.dev: (930.16, 1004.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5327)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723074 reads in 217.725 CPU sec, 7.080 real sec
sorting block 11, #reads = 1076703 mem = 536877854 peak = 825614336
[M::mem_process_seqs] Processed 722742 reads in 152.203 CPU sec, 5.005 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (127, 285979, 103, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (468.89, 394.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.27, 95.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 662, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (797.06, 722.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 489, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (575.34, 541.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722590 sequences (100000113 bp) in 3.593 CPU sec, 3.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286614, 68, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 624, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4726)
[M::mem_pestat] mean and std.dev: (1019.62, 1070.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (205.93, 95.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 422, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3807)
[M::mem_pestat] mean and std.dev: (709.02, 674.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 555, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (855.08, 893.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722102 reads in 214.597 CPU sec, 6.958 real sec
[M::process] read 730612 sequences (100000040 bp) in 2.688 CPU sec, 2.698 real sec...
sorting block 12, #reads = 1076981 mem = 536879900 peak = 825614336
[M::mem_process_seqs] Processed 722366 reads in 165.398 CPU sec, 5.257 real sec
sorting block 13, #reads = 1076765 mem = 536881029 peak = 855228416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 286037, 102, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 307, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (514.13, 465.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.85, 95.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 605, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3156)
[M::mem_pestat] mean and std.dev: (727.93, 634.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 327, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (374.01, 292.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729938 sequences (100000224 bp) in 3.404 CPU sec, 3.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 288564, 67, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 381, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (547.79, 483.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (194.28, 88.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 627, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3094)
[M::mem_pestat] mean and std.dev: (707.28, 661.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 404, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (574.86, 478.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728906 sequences (100000037 bp) in 2.370 CPU sec, 2.367 real sec...
[M::mem_process_seqs] Processed 722590 reads in 216.983 CPU sec, 6.877 real sec
[M::mem_process_seqs] Processed 730612 reads in 152.813 CPU sec, 4.839 real sec
sorting block 14, #reads = 1075769 mem = 536881259 peak = 855228416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288994, 62, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 416, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (470.12, 380.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 496)
[M::mem_pestat] mean and std.dev: (195.48, 89.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 619)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 612, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (718.24, 578.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3415)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 450, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1892)
[M::mem_pestat] mean and std.dev: (525.48, 379.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728752 sequences (100000103 bp) in 3.838 CPU sec, 4.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288158, 63, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 331, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (462.82, 406.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.24, 90.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 454, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (511.73, 492.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 342, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (496.35, 480.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729938 reads in 213.228 CPU sec, 6.767 real sec
[M::process] read 727930 sequences (100000018 bp) in 2.418 CPU sec, 2.420 real sec...
sorting block 15, #reads = 1083934 mem = 536883643 peak = 855228416
[M::mem_process_seqs] Processed 728906 reads in 153.887 CPU sec, 5.260 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 288939, 72, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 444, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379)
[M::mem_pestat] mean and std.dev: (802.62, 784.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.08, 90.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 512, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4435)
[M::mem_pestat] mean and std.dev: (927.19, 1092.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 400, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (471.37, 362.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1081480 mem = 536880957 peak = 855228416
[M::process] read 727282 sequences (100000154 bp) in 3.200 CPU sec, 3.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 288387, 71, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 461, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (595.09, 555.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.42, 91.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 562, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (633.69, 553.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 527, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (574.84, 480.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726892 sequences (100000092 bp) in 2.458 CPU sec, 2.453 real sec...
[M::mem_process_seqs] Processed 728752 reads in 219.462 CPU sec, 7.354 real sec
[M::mem_process_seqs] Processed 727930 reads in 150.153 CPU sec, 4.933 real sec
sorting block 17, #reads = 1082877 mem = 536890930 peak = 855228416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288131, 73, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 572, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (853.02, 900.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 507)
[M::mem_pestat] mean and std.dev: (199.18, 92.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 398, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2409)
[M::mem_pestat] mean and std.dev: (582.51, 592.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 370, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (540.07, 446.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726418 sequences (100000165 bp) in 3.152 CPU sec, 3.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 287640, 56, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 324, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (434.74, 385.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (199.65, 92.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 547, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4497)
[M::mem_pestat] mean and std.dev: (866.28, 927.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 452, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (564.67, 486.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726624 sequences (100000130 bp) in 2.368 CPU sec, 2.369 real sec...
[M::mem_process_seqs] Processed 727282 reads in 216.893 CPU sec, 7.064 real sec
[M::mem_process_seqs] Processed 726892 reads in 147.978 CPU sec, 4.822 real sec
sorting block 18, #reads = 1080486 mem = 536881296 peak = 855228416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287353, 68, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 790, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (686.89, 504.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.47, 93.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 498, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095)
[M::mem_pestat] mean and std.dev: (604.89, 660.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 455, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2998)
[M::mem_pestat] mean and std.dev: (636.23, 519.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726520 sequences (100000234 bp) in 3.476 CPU sec, 3.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 287918, 66, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 372, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (510.88, 445.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.16, 92.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 635, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (741.84, 642.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 637, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3746)
[M::mem_pestat] mean and std.dev: (861.26, 823.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726418 reads in 209.109 CPU sec, 6.752 real sec
[M::process] read 726592 sequences (100000007 bp) in 2.567 CPU sec, 2.576 real sec...
[M::mem_process_seqs] Processed 726624 reads in 148.081 CPU sec, 4.724 real sec
sorting block 19, #reads = 1080696 mem = 536884295 peak = 855228416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287578, 60, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 453, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (652.49, 583.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.74, 92.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 799, 1992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5276)
[M::mem_pestat] mean and std.dev: (1104.31, 1188.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6918)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 396, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (456.96, 343.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1080194 mem = 536878367 peak = 878206976
[M::process] read 725528 sequences (100000108 bp) in 3.197 CPU sec, 3.386 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287493, 80, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 348, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (510.54, 485.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (199.82, 92.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 445, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (549.86, 476.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 314, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (545.34, 550.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725580 sequences (100000291 bp) in 2.492 CPU sec, 2.491 real sec...
[M::mem_process_seqs] Processed 726520 reads in 224.559 CPU sec, 7.182 real sec
[M::mem_process_seqs] Processed 726592 reads in 152.836 CPU sec, 4.859 real sec
sorting block 21, #reads = 1079155 mem = 536879359 peak = 878206976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 286706, 59, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 423, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (580.58, 516.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.30, 92.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 460, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (479.52, 414.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 631, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (814.89, 704.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726070 sequences (100000026 bp) in 3.667 CPU sec, 3.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286781, 68, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 498, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (567.08, 426.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.63, 91.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 784, 1953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5523)
[M::mem_pestat] mean and std.dev: (1006.05, 1037.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 386, 1871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5213)
[M::mem_pestat] mean and std.dev: (918.92, 970.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725528 reads in 217.629 CPU sec, 6.926 real sec
[M::process] read 725280 sequences (100000051 bp) in 2.679 CPU sec, 2.710 real sec...
[M::mem_process_seqs] Processed 725580 reads in 155.956 CPU sec, 5.003 real sec
sorting block 22, #reads = 1078442 mem = 536888221 peak = 878206976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 287696, 52, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 478, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616)
[M::mem_pestat] mean and std.dev: (700.61, 530.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.90, 92.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 481, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (672.84, 653.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 340, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3184)
[M::mem_pestat] mean and std.dev: (574.29, 555.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724536 sequences (100000006 bp) in 3.533 CPU sec, 3.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (126, 286860, 65, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 698, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4347)
[M::mem_pestat] mean and std.dev: (1092.15, 1212.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.57, 92.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 360, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (490.58, 528.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 419, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4753)
[M::mem_pestat] mean and std.dev: (957.81, 935.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724554 sequences (100000029 bp) in 2.430 CPU sec, 2.427 real sec...
[M::mem_process_seqs] Processed 726070 reads in 222.771 CPU sec, 7.153 real sec
sorting block 23, #reads = 1076498 mem = 536878985 peak = 878206976
[M::mem_process_seqs] Processed 725280 reads in 156.690 CPU sec, 5.015 real sec
sorting block 24, #reads = 1078256 mem = 536879176 peak = 928116736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287253, 74, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 454, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (726.31, 681.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.55, 92.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 605, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (702.83, 706.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 416, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (731.81, 727.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723930 sequences (100000109 bp) in 2.745 CPU sec, 2.856 real sec...
[M::process] read 724228 sequences (100000254 bp) in 1.961 CPU sec, 1.968 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286873, 81, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 484, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3194)
[M::mem_pestat] mean and std.dev: (692.68, 632.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.90, 92.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 480, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (643.58, 672.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 386, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (534.58, 472.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724536 reads in 217.272 CPU sec, 6.980 real sec
[M::mem_process_seqs] Processed 724554 reads in 154.714 CPU sec, 4.955 real sec
sorting block 25, #reads = 1077380 mem = 536893149 peak = 928116736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 287136, 83, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 527, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (578.00, 418.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.48, 93.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 611, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080)
[M::mem_pestat] mean and std.dev: (1019.48, 1109.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 467, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4319)
[M::mem_pestat] mean and std.dev: (755.12, 809.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723832 sequences (100000189 bp) in 3.224 CPU sec, 3.373 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 286744, 62, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 389, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (631.93, 649.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.43, 93.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 506, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (448.39, 344.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 471, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (540.99, 370.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723788 sequences (100000175 bp) in 2.380 CPU sec, 2.383 real sec...
[M::mem_process_seqs] Processed 723930 reads in 210.186 CPU sec, 6.677 real sec
[M::mem_process_seqs] Processed 724228 reads in 150.708 CPU sec, 4.822 real sec
sorting block 26, #reads = 1077605 mem = 536880207 peak = 928116736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286523, 87, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 448, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (533.29, 441.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.85, 93.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 559, 2213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6147)
[M::mem_pestat] mean and std.dev: (998.33, 1224.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 386, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1681)
[M::mem_pestat] mean and std.dev: (507.14, 337.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724742 sequences (100000231 bp) in 3.476 CPU sec, 3.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286791, 66, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 613, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3823)
[M::mem_pestat] mean and std.dev: (870.79, 787.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.67, 94.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 585, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4545)
[M::mem_pestat] mean and std.dev: (925.22, 1024.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 518, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (560.73, 458.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731532 sequences (100000098 bp) in 2.470 CPU sec, 2.472 real sec...
[M::mem_process_seqs] Processed 723832 reads in 223.183 CPU sec, 7.132 real sec
sorting block 27, #reads = 1077771 mem = 536884698 peak = 928116736
[M::mem_process_seqs] Processed 723788 reads in 157.667 CPU sec, 5.010 real sec
sorting block 28, #reads = 1076577 mem = 536877709 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287152, 71, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 493, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (626.31, 575.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.83, 93.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 555, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (656.44, 566.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 473, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3336)
[M::mem_pestat] mean and std.dev: (703.86, 648.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730686 sequences (100000260 bp) in 3.598 CPU sec, 3.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288834, 68, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 520, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5092)
[M::mem_pestat] mean and std.dev: (1021.93, 1088.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 175, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 489)
[M::mem_pestat] mean and std.dev: (193.43, 88.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 610)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 683, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4128)
[M::mem_pestat] mean and std.dev: (944.55, 881.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 390, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (498.66, 435.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730712 sequences (100000130 bp) in 2.300 CPU sec, 2.293 real sec...
[M::mem_process_seqs] Processed 724742 reads in 221.424 CPU sec, 7.032 real sec
[M::mem_process_seqs] Processed 731532 reads in 153.684 CPU sec, 4.887 real sec
sorting block 29, #reads = 1075812 mem = 536878190 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 289358, 72, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 448, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (490.91, 391.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (194.86, 89.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 772, 1612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4360)
[M::mem_pestat] mean and std.dev: (850.64, 756.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5734)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 314, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (443.34, 372.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729378 sequences (100000252 bp) in 3.349 CPU sec, 3.522 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 289567, 55, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 464, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (670.42, 618.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (194.65, 89.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 334, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2904)
[M::mem_pestat] mean and std.dev: (600.96, 731.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 405, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (492.98, 317.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728162 sequences (100000261 bp) in 2.279 CPU sec, 2.283 real sec...
[M::mem_process_seqs] Processed 730686 reads in 214.037 CPU sec, 6.816 real sec
sorting block 30, #reads = 1080557 mem = 536882368 peak = 985767936
[M::mem_process_seqs] Processed 730712 reads in 152.538 CPU sec, 4.895 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288575, 76, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 322, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (472.60, 414.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.15, 90.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 623, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (745.51, 709.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 307, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2327)
[M::mem_pestat] mean and std.dev: (534.43, 491.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727666 sequences (100000088 bp) in 3.465 CPU sec, 3.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288341, 68, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 418, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (705.05, 643.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (198.38, 91.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 632)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 450, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (488.94, 378.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 775, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4484)
[M::mem_pestat] mean and std.dev: (1040.77, 1076.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726986 sequences (100000043 bp) in 2.540 CPU sec, 2.541 real sec...
[M::mem_process_seqs] Processed 729378 reads in 215.484 CPU sec, 6.882 real sec
sorting block 31, #reads = 1082843 mem = 536878997 peak = 985767936
[M::mem_process_seqs] Processed 728162 reads in 151.789 CPU sec, 4.804 real sec
sorting block 32, #reads = 1080868 mem = 536880773 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288208, 61, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 462, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2926)
[M::mem_pestat] mean and std.dev: (582.86, 496.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.67, 91.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 511, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4806)
[M::mem_pestat] mean and std.dev: (852.00, 1061.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6377)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 519, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (516.07, 398.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726612 sequences (100000101 bp) in 3.709 CPU sec, 3.951 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287889, 89, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 293, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (357.66, 243.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (199.80, 92.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 746, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (956.21, 861.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 384, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (499.50, 528.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727666 reads in 204.089 CPU sec, 6.495 real sec
[M::mem_process_seqs] Processed 726986 reads in 144.972 CPU sec, 4.586 real sec
[M::process] read 726510 sequences (100000164 bp) in 2.908 CPU sec, 3.001 real sec...
sorting block 33, #reads = 1079797 mem = 536888769 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288032, 71, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 347, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (480.10, 410.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.75, 93.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 638, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (718.08, 631.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 333, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (524.84, 485.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725642 sequences (100000116 bp) in 3.388 CPU sec, 3.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287424, 63, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 415, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (543.41, 503.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.41, 92.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 469, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (803.59, 750.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 285, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (461.67, 387.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726612 reads in 212.419 CPU sec, 6.755 real sec
[M::process] read 725584 sequences (100000073 bp) in 2.865 CPU sec, 2.898 real sec...
sorting block 34, #reads = 1080353 mem = 536879568 peak = 985767936
[M::mem_process_seqs] Processed 726510 reads in 152.453 CPU sec, 5.087 real sec
sorting block 35, #reads = 1079340 mem = 536883886 peak = 985767936
[M::process] read 726144 sequences (100000216 bp) in 3.765 CPU sec, 4.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287771, 80, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 366, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2389)
[M::mem_pestat] mean and std.dev: (516.49, 488.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.37, 93.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 690, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (770.79, 603.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 463, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452)
[M::mem_pestat] mean and std.dev: (661.06, 559.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725584 reads in 120.339 CPU sec, 3.792 real sec
[M::process] read 725536 sequences (100000043 bp) in 2.714 CPU sec, 2.749 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286806, 82, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 555, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3199)
[M::mem_pestat] mean and std.dev: (703.15, 601.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.16, 93.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 564, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (675.16, 689.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 365, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (624.00, 624.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287478, 64, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 524, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (609.96, 565.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.88, 92.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 468, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4729)
[M::mem_pestat] mean and std.dev: (833.03, 1011.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 439, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (511.11, 370.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725642 reads in 329.284 CPU sec, 10.725 real sec
[M::process] read 725454 sequences (100000049 bp) in 2.810 CPU sec, 2.882 real sec...
sorting block 36, #reads = 1077757 mem = 536878949 peak = 985767936
[M::mem_process_seqs] Processed 726144 reads in 180.462 CPU sec, 5.916 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287086, 68, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 434, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (565.75, 432.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.94, 92.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 568, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (770.14, 817.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4165)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 345, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (531.18, 461.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1079694 mem = 536883610 peak = 985767936
[M::process] read 725178 sequences (100000145 bp) in 3.522 CPU sec, 3.776 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286706, 100, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 476, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3755)
[M::mem_pestat] mean and std.dev: (765.11, 768.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.24, 91.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 593, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4117)
[M::mem_pestat] mean and std.dev: (838.88, 823.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 447, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (562.34, 433.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725536 reads in 211.410 CPU sec, 6.923 real sec
[M::process] read 724642 sequences (100000287 bp) in 2.752 CPU sec, 2.820 real sec...
[M::mem_process_seqs] Processed 725454 reads in 149.351 CPU sec, 4.965 real sec
sorting block 38, #reads = 1077521 mem = 536884278 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286748, 86, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 367, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (650.59, 680.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.51, 92.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 561, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2832)
[M::mem_pestat] mean and std.dev: (622.44, 540.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 435, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (567.82, 482.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723714 sequences (100000233 bp) in 3.743 CPU sec, 4.207 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287057, 71, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 515, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3313)
[M::mem_pestat] mean and std.dev: (746.51, 700.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.48, 92.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 987, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (881.34, 754.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 745, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521)
[M::mem_pestat] mean and std.dev: (895.98, 757.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725178 reads in 211.634 CPU sec, 6.980 real sec
[M::mem_process_seqs] Processed 724642 reads in 152.437 CPU sec, 4.818 real sec
[M::process] read 724226 sequences (100000007 bp) in 2.824 CPU sec, 2.903 real sec...
sorting block 39, #reads = 1077919 mem = 536878612 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286586, 60, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 510, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (605.92, 523.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (201.83, 92.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 665, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2921)
[M::mem_pestat] mean and std.dev: (727.82, 605.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 363, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1965)
[M::mem_pestat] mean and std.dev: (490.57, 445.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724534 sequences (100000030 bp) in 3.342 CPU sec, 3.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286185, 65, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 574, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (684.01, 677.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.12, 93.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 486, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (665.45, 602.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 490, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (607.58, 465.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723714 reads in 213.091 CPU sec, 6.792 real sec
[M::process] read 724552 sequences (100000202 bp) in 2.623 CPU sec, 2.652 real sec...
sorting block 40, #reads = 1077282 mem = 536876848 peak = 985767936
[M::mem_process_seqs] Processed 724226 reads in 154.905 CPU sec, 5.207 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286933, 75, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 555, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3216)
[M::mem_pestat] mean and std.dev: (686.65, 628.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 41, #reads = 1075089 mem = 536895542 peak = 985767936
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.48, 93.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 604, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (694.71, 606.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 581, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (658.73, 511.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724034 sequences (100000011 bp) in 3.387 CPU sec, 3.681 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 286594, 86, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 410, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2117)
[M::mem_pestat] mean and std.dev: (546.09, 446.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.21, 92.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 629, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3292)
[M::mem_pestat] mean and std.dev: (742.25, 712.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (334, 686, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4126)
[M::mem_pestat] mean and std.dev: (803.21, 640.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725614 sequences (100000129 bp) in 2.550 CPU sec, 2.550 real sec...
[M::mem_process_seqs] Processed 724534 reads in 223.609 CPU sec, 7.408 real sec
[M::mem_process_seqs] Processed 724552 reads in 153.292 CPU sec, 5.029 real sec
sorting block 42, #reads = 1076556 mem = 536885618 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 286794, 83, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 357, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (395.95, 283.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (202.09, 93.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 592, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2992)
[M::mem_pestat] mean and std.dev: (690.88, 573.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 573, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (741.00, 659.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729960 sequences (100000132 bp) in 3.099 CPU sec, 3.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 287099, 69, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 430, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (587.31, 546.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.32, 92.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 432, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (533.86, 416.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 747, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4392)
[M::mem_pestat] mean and std.dev: (994.51, 992.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729482 sequences (100000022 bp) in 2.470 CPU sec, 2.475 real sec...
[M::mem_process_seqs] Processed 724034 reads in 217.694 CPU sec, 7.079 real sec
sorting block 43, #reads = 1076428 mem = 536880427 peak = 985767936
[M::mem_process_seqs] Processed 725614 reads in 153.584 CPU sec, 5.022 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288829, 68, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 329, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (478.41, 400.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (194.99, 89.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 482, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (638.06, 557.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 302, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2340)
[M::mem_pestat] mean and std.dev: (507.12, 513.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728886 sequences (100000172 bp) in 3.275 CPU sec, 3.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288831, 60, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 463, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (629.21, 587.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.60, 89.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 614, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (627.36, 631.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 597, 1942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5408)
[M::mem_pestat] mean and std.dev: (1079.97, 1217.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729090 sequences (100000297 bp) in 2.640 CPU sec, 2.639 real sec...
[M::mem_process_seqs] Processed 729960 reads in 210.463 CPU sec, 6.824 real sec
sorting block 44, #reads = 1074797 mem = 536884242 peak = 985767936
[M::mem_process_seqs] Processed 729482 reads in 146.460 CPU sec, 4.909 real sec
sorting block 45, #reads = 1082578 mem = 536877950 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 289231, 83, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 687, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (944.94, 870.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.40, 89.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 423, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (623.26, 612.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 488, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3634)
[M::mem_pestat] mean and std.dev: (802.65, 736.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728482 sequences (100000175 bp) in 3.414 CPU sec, 3.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 288961, 61, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 364, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (446.20, 344.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (196.94, 90.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 513, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (527.54, 379.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 723, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (744.82, 603.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727810 sequences (100000013 bp) in 2.570 CPU sec, 2.568 real sec...
[M::mem_process_seqs] Processed 728886 reads in 212.709 CPU sec, 7.007 real sec
[M::mem_process_seqs] Processed 729090 reads in 147.763 CPU sec, 4.841 real sec
sorting block 46, #reads = 1082078 mem = 536880434 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 288395, 82, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 400, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (714.77, 707.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 503)
[M::mem_pestat] mean and std.dev: (197.65, 91.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 628)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 629, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (717.51, 731.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 329, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (456.45, 347.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727336 sequences (100000046 bp) in 3.344 CPU sec, 3.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287786, 59, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 322, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (521.30, 445.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2962)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.47, 91.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 482, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (495.25, 457.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 369, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (645.09, 626.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726886 sequences (100000163 bp) in 2.660 CPU sec, 2.654 real sec...
[M::mem_process_seqs] Processed 728482 reads in 209.379 CPU sec, 6.798 real sec
sorting block 47, #reads = 1082884 mem = 536889933 peak = 985767936
[M::mem_process_seqs] Processed 727810 reads in 146.730 CPU sec, 4.873 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 288582, 82, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 506, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (807.50, 904.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (199.67, 92.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 832, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3728)
[M::mem_pestat] mean and std.dev: (931.12, 744.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 340, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (413.79, 304.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1080114 mem = 536879497 peak = 985767936
[M::process] read 726546 sequences (100000086 bp) in 3.203 CPU sec, 3.304 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288026, 76, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 291, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (368.10, 253.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (200.32, 93.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 641)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 675, 1756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4690)
[M::mem_pestat] mean and std.dev: (860.09, 950.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 340, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (624.74, 534.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726596 sequences (100000066 bp) in 1.950 CPU sec, 1.948 real sec...
[M::mem_process_seqs] Processed 727336 reads in 208.385 CPU sec, 6.853 real sec
[M::mem_process_seqs] Processed 726886 reads in 142.848 CPU sec, 4.712 real sec
sorting block 49, #reads = 1080780 mem = 536879604 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287702, 59, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 397, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2276)
[M::mem_pestat] mean and std.dev: (571.41, 541.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.00, 92.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 443, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (733.00, 792.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 548, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (792.27, 687.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727584 sequences (100000038 bp) in 3.179 CPU sec, 3.326 real sec...
[M::process] read 728168 sequences (100000048 bp) in 1.970 CPU sec, 1.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287740, 69, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 747, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3759)
[M::mem_pestat] mean and std.dev: (794.74, 727.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.47, 93.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 410, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (556.52, 551.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3247)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 396, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (549.26, 440.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726546 reads in 209.009 CPU sec, 6.807 real sec
[M::mem_process_seqs] Processed 726596 reads in 145.431 CPU sec, 4.800 real sec
sorting block 50, #reads = 1079352 mem = 536881642 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 287940, 79, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 546, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (930.91, 987.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 507)
[M::mem_pestat] mean and std.dev: (199.10, 92.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 658, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (579.35, 382.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 408, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (593.79, 543.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726544 sequences (100000271 bp) in 2.588 CPU sec, 2.707 real sec...
[M::process] read 725658 sequences (100000276 bp) in 1.980 CPU sec, 1.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 288016, 61, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 567, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3445)
[M::mem_pestat] mean and std.dev: (783.71, 765.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.76, 88.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 605, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (720.34, 624.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 330, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (536.70, 516.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727584 reads in 212.067 CPU sec, 6.928 real sec
sorting block 51, #reads = 1079750 mem = 536883910 peak = 985767936
[M::mem_process_seqs] Processed 728168 reads in 147.162 CPU sec, 4.920 real sec
sorting block 52, #reads = 1078984 mem = 536876931 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 287881, 71, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 373, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (564.03, 455.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.68, 91.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 511, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (820.85, 806.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 507, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4190)
[M::mem_pestat] mean and std.dev: (874.41, 850.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724848 sequences (100000059 bp) in 3.125 CPU sec, 3.355 real sec...
[M::process] read 725278 sequences (100000121 bp) in 2.340 CPU sec, 2.341 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (136, 286693, 60, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 442, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3227)
[M::mem_pestat] mean and std.dev: (711.45, 639.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.55, 91.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 602, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (715.30, 695.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4478)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 396, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (643.34, 602.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726544 reads in 215.707 CPU sec, 7.054 real sec
[M::process] read 723678 sequences (100000175 bp) in 1.924 CPU sec, 1.933 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 286605, 49, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 438, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (761.94, 757.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.35, 91.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 968, 2832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7762)
[M::mem_pestat] mean and std.dev: (1775.50, 1957.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 514, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (587.74, 459.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724848 reads in 116.688 CPU sec, 3.940 real sec
sorting block 53, #reads = 1077756 mem = 536886315 peak = 985767936
[M::mem_process_seqs] Processed 725658 reads in 304.645 CPU sec, 9.937 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286983, 57, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 389, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (576.01, 503.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.70, 92.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 708, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4012)
[M::mem_pestat] mean and std.dev: (889.04, 895.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 551, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3437)
[M::mem_pestat] mean and std.dev: (778.39, 743.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1075368 mem = 536880424 peak = 985767936
[M::process] read 723304 sequences (100000300 bp) in 3.238 CPU sec, 3.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286180, 77, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 263, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (328.38, 253.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.34, 91.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 732, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4027)
[M::mem_pestat] mean and std.dev: (828.82, 761.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 489, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (546.62, 469.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725278 reads in 240.959 CPU sec, 7.713 real sec
[M::process] read 724006 sequences (100000140 bp) in 2.713 CPU sec, 2.783 real sec...
[M::mem_process_seqs] Processed 723678 reads in 152.783 CPU sec, 5.027 real sec
sorting block 55, #reads = 1075581 mem = 536876488 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286170, 61, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 489, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (529.97, 390.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (202.02, 91.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 636)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 522, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3193)
[M::mem_pestat] mean and std.dev: (711.81, 663.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 439, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4123)
[M::mem_pestat] mean and std.dev: (756.21, 808.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723994 sequences (100000187 bp) in 3.072 CPU sec, 3.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 287019, 54, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 379, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3025)
[M::mem_pestat] mean and std.dev: (560.42, 499.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.82, 92.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 774, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4254)
[M::mem_pestat] mean and std.dev: (933.39, 919.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 433, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (527.45, 402.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724050 sequences (100000180 bp) in 2.370 CPU sec, 2.364 real sec...
[M::mem_process_seqs] Processed 723304 reads in 214.726 CPU sec, 7.025 real sec
sorting block 56, #reads = 1076187 mem = 536880796 peak = 985767936
[M::mem_process_seqs] Processed 724006 reads in 150.070 CPU sec, 4.967 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286563, 80, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 373, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (463.27, 403.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.30, 93.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 671, 1638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4540)
[M::mem_pestat] mean and std.dev: (854.36, 839.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 400, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (632.43, 646.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724206 sequences (100000301 bp) in 2.982 CPU sec, 3.191 real sec...
[M::process] read 735302 sequences (100000200 bp) in 1.870 CPU sec, 1.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286746, 77, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 474, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (603.92, 510.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3451)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.63, 92.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 708, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3296)
[M::mem_pestat] mean and std.dev: (701.64, 592.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 498, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769)
[M::mem_pestat] mean and std.dev: (618.89, 530.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723994 reads in 213.888 CPU sec, 6.995 real sec
sorting block 57, #reads = 1076297 mem = 536884871 peak = 985767936
[M::mem_process_seqs] Processed 724050 reads in 148.797 CPU sec, 4.912 real sec
sorting block 58, #reads = 1075441 mem = 536882169 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286420, 72, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 440, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (565.58, 450.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.41, 93.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 652, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (909.80, 968.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 359, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (628.33, 689.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733776 sequences (100000168 bp) in 3.325 CPU sec, 3.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 290412, 73, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 496, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (559.97, 415.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 169, 234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 454)
[M::mem_pestat] mean and std.dev: (184.65, 80.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 564)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 423, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3659)
[M::mem_pestat] mean and std.dev: (636.57, 735.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 405, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (502.58, 378.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731106 sequences (100000251 bp) in 2.350 CPU sec, 2.357 real sec...
[M::mem_process_seqs] Processed 724206 reads in 215.236 CPU sec, 6.984 real sec
[M::mem_process_seqs] Processed 735302 reads in 151.637 CPU sec, 4.803 real sec
sorting block 59, #reads = 1075591 mem = 536886239 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290361, 57, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (450.76, 389.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 172, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 467)
[M::mem_pestat] mean and std.dev: (188.01, 83.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 581)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 594, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4588)
[M::mem_pestat] mean and std.dev: (884.52, 878.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 417, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (544.24, 464.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730026 sequences (100000010 bp) in 3.150 CPU sec, 3.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 289318, 51, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 364, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (576.38, 505.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (191.49, 86.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 543, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3832)
[M::mem_pestat] mean and std.dev: (823.04, 878.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 315, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (473.56, 456.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728700 sequences (100000197 bp) in 2.240 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 733776 reads in 202.224 CPU sec, 6.407 real sec
sorting block 60, #reads = 1080890 mem = 536877431 peak = 985767936
[M::mem_process_seqs] Processed 731106 reads in 138.805 CPU sec, 4.726 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 289216, 56, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 315, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (419.82, 379.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (192.99, 87.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 768, 1556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4016)
[M::mem_pestat] mean and std.dev: (868.78, 761.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 545, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (723.62, 626.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728372 sequences (100000137 bp) in 3.310 CPU sec, 3.462 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 288720, 84, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 347, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2289)
[M::mem_pestat] mean and std.dev: (490.93, 429.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.66, 88.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 573, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (790.20, 749.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 506, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651)
[M::mem_pestat] mean and std.dev: (763.66, 817.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728392 sequences (100000051 bp) in 2.390 CPU sec, 2.391 real sec...
[M::mem_process_seqs] Processed 730026 reads in 207.187 CPU sec, 6.889 real sec
sorting block 61, #reads = 1081911 mem = 536882472 peak = 985767936
[M::mem_process_seqs] Processed 728700 reads in 142.189 CPU sec, 4.667 real sec
sorting block 62, #reads = 1081379 mem = 536881687 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288657, 62, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 580, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (595.24, 515.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.00, 89.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 567, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4005)
[M::mem_pestat] mean and std.dev: (769.38, 783.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 368, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (506.12, 422.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728264 sequences (100000140 bp) in 3.205 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 288093, 77, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 329, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (399.64, 340.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.54, 90.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 674, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (706.27, 589.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 549, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551)
[M::mem_pestat] mean and std.dev: (657.03, 509.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727548 sequences (100000069 bp) in 2.000 CPU sec, 2.006 real sec...
[M::mem_process_seqs] Processed 728372 reads in 205.237 CPU sec, 6.674 real sec
[M::mem_process_seqs] Processed 728392 reads in 142.582 CPU sec, 4.678 real sec
sorting block 63, #reads = 1078137 mem = 536877132 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 288543, 94, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 551, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (593.15, 474.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.74, 90.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 602, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (569.82, 484.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 541, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (573.49, 458.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727168 sequences (100000057 bp) in 3.004 CPU sec, 3.084 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287641, 78, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 445, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3709)
[M::mem_pestat] mean and std.dev: (897.34, 957.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.41, 90.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 469, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4841)
[M::mem_pestat] mean and std.dev: (1153.00, 1321.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 456, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2044)
[M::mem_pestat] mean and std.dev: (542.78, 422.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726678 sequences (100000241 bp) in 2.580 CPU sec, 2.581 real sec...
[M::mem_process_seqs] Processed 728264 reads in 209.771 CPU sec, 6.779 real sec
sorting block 64, #reads = 1078215 mem = 536880023 peak = 985767936
[M::mem_process_seqs] Processed 727548 reads in 144.448 CPU sec, 4.719 real sec
sorting block 65, #reads = 1079409 mem = 536882346 peak = 985767936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (127, 287595, 90, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 432, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (621.74, 553.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.18, 91.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 692, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (758.93, 650.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 449, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (652.08, 596.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726408 sequences (100000131 bp) in 3.129 CPU sec, 3.203 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287616, 84, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 404, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (496.90, 456.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.80, 91.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 589, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (636.33, 588.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 665, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4355)
[M::mem_pestat] mean and std.dev: (973.29, 990.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5734)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726398 sequences (100000224 bp) in 2.650 CPU sec, 2.656 real sec...
[M::mem_process_seqs] Processed 727168 reads in 211.516 CPU sec, 6.861 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287319, 83, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 406, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (680.04, 704.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.82, 91.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 622, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (816.38, 795.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 455, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (520.90, 420.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725488 sequences (100000108 bp) in 2.695 CPU sec, 2.702 real sec...
[M::mem_process_seqs] Processed 726408 reads in 122.054 CPU sec, 4.037 real sec
sorting block 66, #reads = 1077036 mem = 536883492 peak = 985767936
[M::mem_process_seqs] Processed 726678 reads in 307.666 CPU sec, 9.941 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 287021, 79, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 347, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (403.97, 280.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (198.29, 90.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 503, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (529.17, 475.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 550, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3604)
[M::mem_pestat] mean and std.dev: (869.75, 895.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1076591 mem = 536881287 peak = 998518784
[M::process] read 725428 sequences (100000006 bp) in 3.161 CPU sec, 3.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286849, 88, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 396, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (742.93, 774.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.77, 91.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 631, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (551.17, 423.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 566, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3326)
[M::mem_pestat] mean and std.dev: (742.26, 698.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726398 reads in 230.428 CPU sec, 7.322 real sec
[M::process] read 725618 sequences (100000138 bp) in 2.406 CPU sec, 2.476 real sec...
[M::mem_process_seqs] Processed 725488 reads in 143.136 CPU sec, 4.708 real sec
sorting block 68, #reads = 1075248 mem = 536879666 peak = 998518784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 286932, 73, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 488, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (741.70, 674.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.68, 91.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 896, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5037)
[M::mem_pestat] mean and std.dev: (974.23, 832.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 510, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (548.45, 414.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725034 sequences (100000274 bp) in 3.190 CPU sec, 3.321 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286868, 77, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 479, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (546.00, 461.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.93, 91.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 634, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3766)
[M::mem_pestat] mean and std.dev: (852.72, 866.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 458, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (647.37, 616.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724668 sequences (100000013 bp) in 2.580 CPU sec, 2.581 real sec...
[M::mem_process_seqs] Processed 725428 reads in 213.400 CPU sec, 6.960 real sec
sorting block 69, #reads = 1075196 mem = 536883885 peak = 998518784
[M::mem_process_seqs] Processed 725618 reads in 148.093 CPU sec, 4.857 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286543, 69, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 368, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4030)
[M::mem_pestat] mean and std.dev: (663.95, 672.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.36, 91.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 534, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (549.58, 411.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 432, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (595.96, 496.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725610 sequences (100000249 bp) in 2.960 CPU sec, 3.089 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287123, 72, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 498, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (683.14, 607.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.94, 92.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 453, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3339)
[M::mem_pestat] mean and std.dev: (547.00, 494.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 458, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (578.81, 542.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724882 sequences (100000204 bp) in 2.450 CPU sec, 2.441 real sec...
[M::mem_process_seqs] Processed 725034 reads in 208.733 CPU sec, 6.772 real sec
sorting block 70, #reads = 1075891 mem = 536878822 peak = 998518784
[M::mem_process_seqs] Processed 724668 reads in 144.425 CPU sec, 4.878 real sec
sorting block 71, #reads = 1075930 mem = 536880983 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 287248, 86, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 360, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (401.90, 314.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.37, 92.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 635, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (834.70, 738.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 583, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2842)
[M::mem_pestat] mean and std.dev: (674.11, 598.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725194 sequences (100000107 bp) in 3.704 CPU sec, 3.859 real sec...
[M::process] read 736688 sequences (100000295 bp) in 2.140 CPU sec, 2.136 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 287179, 81, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 339, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (495.09, 455.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.67, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 533, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4825)
[M::mem_pestat] mean and std.dev: (993.68, 1162.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 442, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186)
[M::mem_pestat] mean and std.dev: (521.55, 368.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725610 reads in 218.777 CPU sec, 7.219 real sec
[M::mem_process_seqs] Processed 724882 reads in 243.623 CPU sec, 8.209 real sec
sorting block 72, #reads = 1075255 mem = 536883161 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 286872, 52, 130)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 632, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4205)
[M::mem_pestat] mean and std.dev: (927.06, 903.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (201.10, 92.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 577, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2584)
[M::mem_pestat] mean and std.dev: (678.67, 562.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 568, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3508)
[M::mem_pestat] mean and std.dev: (752.71, 644.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 736460 sequences (100000003 bp) in 3.211 CPU sec, 3.320 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 291062, 56, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 410, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (545.85, 506.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 168, 233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 451)
[M::mem_pestat] mean and std.dev: (183.72, 80.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 560)
[M::process] read 734886 sequences (100000072 bp) in 2.520 CPU sec, 2.520 real sec...
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 1031, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4030)
[M::mem_pestat] mean and std.dev: (1055.43, 977.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 409, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (578.33, 494.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725194 reads in 221.321 CPU sec, 7.184 real sec
sorting block 73, #reads = 1075126 mem = 536880933 peak = 1059422208
[M::mem_process_seqs] Processed 736688 reads in 156.690 CPU sec, 4.965 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 291466, 74, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 439, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (662.89, 623.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 169, 234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 454)
[M::mem_pestat] mean and std.dev: (184.45, 80.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 564)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 585, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (755.46, 728.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 292, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (415.93, 332.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733050 sequences (100000159 bp) in 3.573 CPU sec, 3.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290632, 65, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 395, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (629.91, 554.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 170, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 458)
[M::mem_pestat] mean and std.dev: (186.03, 81.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 569)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 498, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (757.85, 750.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 356, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (780.54, 798.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732504 sequences (100000274 bp) in 2.470 CPU sec, 2.472 real sec...
[M::mem_process_seqs] Processed 736460 reads in 221.971 CPU sec, 7.031 real sec
sorting block 74, #reads = 1078040 mem = 536879624 peak = 1059422208
[M::mem_process_seqs] Processed 734886 reads in 157.539 CPU sec, 5.382 real sec
sorting block 75, #reads = 1079057 mem = 536882502 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 290097, 87, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 402, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2262)
[M::mem_pestat] mean and std.dev: (523.14, 509.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 172, 240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 468)
[M::mem_pestat] mean and std.dev: (189.16, 84.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 582)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 438, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (597.43, 527.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 525, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (647.91, 660.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731670 sequences (100000165 bp) in 3.242 CPU sec, 3.430 real sec...
[M::process] read 731024 sequences (100000161 bp) in 1.920 CPU sec, 1.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 289883, 73, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 365, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (465.40, 452.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (190.20, 85.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 563, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (730.23, 762.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 490, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (780.05, 698.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 733050 reads in 221.922 CPU sec, 7.417 real sec
sorting block 76, #reads = 1077311 mem = 536880268 peak = 1059422208
[M::mem_process_seqs] Processed 732504 reads in 154.308 CPU sec, 5.024 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 289777, 75, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 422, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (496.82, 441.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.08, 87.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 400, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (541.33, 516.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 362, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (599.79, 543.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730976 sequences (100000256 bp) in 3.412 CPU sec, 3.532 real sec...
[M::process] read 730262 sequences (100000130 bp) in 2.420 CPU sec, 2.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 289988, 53, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 373, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (471.72, 396.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 477)
[M::mem_pestat] mean and std.dev: (191.05, 86.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 578, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (640.00, 511.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 500, 1613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4393)
[M::mem_pestat] mean and std.dev: (1008.57, 1165.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731024 reads in 218.532 CPU sec, 7.013 real sec
sorting block 77, #reads = 1077356 mem = 536887617 peak = 1059422208
[M::mem_process_seqs] Processed 731670 reads in 243.907 CPU sec, 8.024 real sec
sorting block 78, #reads = 1077206 mem = 536879951 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 289825, 50, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 371, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (481.31, 399.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.27, 87.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 500, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (603.15, 453.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 336, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (354.09, 261.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729814 sequences (100000065 bp) in 2.689 CPU sec, 2.792 real sec...
[M::process] read 728890 sequences (100000010 bp) in 2.519 CPU sec, 2.522 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 289327, 69, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 457, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (631.43, 561.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (194.36, 88.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 600, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (672.41, 570.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 368, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (592.36, 538.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730976 reads in 206.808 CPU sec, 6.737 real sec
[M::mem_process_seqs] Processed 730262 reads in 140.410 CPU sec, 4.644 real sec
sorting block 79, #reads = 1079426 mem = 536883523 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 288878, 69, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 392, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (620.44, 567.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (195.21, 89.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 1067, 1969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (1179.13, 1047.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 453, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (569.77, 441.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728388 sequences (100000257 bp) in 2.985 CPU sec, 3.124 real sec...
[M::process] read 727252 sequences (100000195 bp) in 2.030 CPU sec, 2.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288044, 60, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 359, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (423.57, 331.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.71, 89.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 427, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (640.82, 636.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 379, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1921)
[M::mem_pestat] mean and std.dev: (492.55, 415.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729814 reads in 210.192 CPU sec, 6.867 real sec
[M::mem_process_seqs] Processed 728890 reads in 144.045 CPU sec, 4.730 real sec
sorting block 80, #reads = 1078944 mem = 536878570 peak = 1059422208
[M::process] read 726918 sequences (100000135 bp) in 3.107 CPU sec, 3.203 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287389, 66, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 552, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (597.27, 480.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.93, 90.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 521, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (694.59, 732.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 386, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (661.65, 598.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726858 sequences (100000174 bp) in 2.490 CPU sec, 2.490 real sec...
[M::mem_process_seqs] Processed 727252 reads in 123.369 CPU sec, 3.892 real sec
sorting block 81, #reads = 1078228 mem = 536878993 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288040, 73, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 363, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (562.51, 569.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.47, 89.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 592, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (705.91, 655.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 268, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (452.78, 431.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287661, 76, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 607, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (664.90, 599.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.12, 90.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 693, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959)
[M::mem_pestat] mean and std.dev: (816.59, 836.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 533, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (591.69, 486.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726332 sequences (100000230 bp) in 2.113 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 728388 reads in 329.323 CPU sec, 10.586 real sec
[M::mem_process_seqs] Processed 726918 reads in 175.993 CPU sec, 5.639 real sec
sorting block 82, #reads = 1075059 mem = 536878732 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287236, 74, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 397, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (514.96, 482.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.06, 90.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 387, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2178)
[M::mem_pestat] mean and std.dev: (444.13, 396.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 607, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3524)
[M::mem_pestat] mean and std.dev: (816.17, 759.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726098 sequences (100000287 bp) in 3.094 CPU sec, 3.215 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (130, 287476, 67, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 381, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2338)
[M::mem_pestat] mean and std.dev: (498.10, 392.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.61, 90.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 499, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (603.86, 579.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 503, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (695.16, 690.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724758 sequences (100000080 bp) in 2.399 CPU sec, 2.401 real sec...
[M::mem_process_seqs] Processed 726858 reads in 212.886 CPU sec, 6.776 real sec
sorting block 83, #reads = 1076745 mem = 536879368 peak = 1059422208
[M::mem_process_seqs] Processed 726332 reads in 146.239 CPU sec, 4.745 real sec
sorting block 84, #reads = 1076202 mem = 536881162 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286849, 62, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 344, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (604.54, 606.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.71, 90.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 530, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (533.42, 470.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 441, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (647.44, 533.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724966 sequences (100000219 bp) in 3.387 CPU sec, 3.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286739, 57, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 561, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3529)
[M::mem_pestat] mean and std.dev: (822.93, 739.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.97, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 499, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3373)
[M::mem_pestat] mean and std.dev: (611.33, 635.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 587, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4175)
[M::mem_pestat] mean and std.dev: (873.07, 943.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725448 sequences (100000168 bp) in 2.440 CPU sec, 2.436 real sec...
[M::mem_process_seqs] Processed 726098 reads in 211.512 CPU sec, 6.820 real sec
[M::mem_process_seqs] Processed 724758 reads in 145.353 CPU sec, 4.805 real sec
sorting block 85, #reads = 1074677 mem = 536882043 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286768, 84, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 469, 1806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994)
[M::mem_pestat] mean and std.dev: (888.51, 1084.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.76, 92.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 445, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (623.94, 597.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 594, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (725.85, 640.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729126 sequences (100000224 bp) in 3.287 CPU sec, 3.468 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286535, 73, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 370, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (497.64, 465.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.24, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 753, 1962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5192)
[M::mem_pestat] mean and std.dev: (1065.94, 1130.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 510, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (703.70, 641.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734934 sequences (100000292 bp) in 2.440 CPU sec, 2.436 real sec...
[M::mem_process_seqs] Processed 724966 reads in 210.738 CPU sec, 6.869 real sec
sorting block 86, #reads = 1076316 mem = 536878443 peak = 1059422208
[M::mem_process_seqs] Processed 725448 reads in 147.319 CPU sec, 4.820 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287624, 66, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 391, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (670.79, 676.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485)
[M::mem_pestat] mean and std.dev: (193.91, 87.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 604)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 677, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5849)
[M::mem_pestat] mean and std.dev: (1191.15, 1325.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 441, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (673.98, 670.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3878)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733550 sequences (100000286 bp) in 2.965 CPU sec, 3.050 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 290785, 66, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 429, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (632.31, 604.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 170, 237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 463)
[M::mem_pestat] mean and std.dev: (186.70, 82.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 576)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 564, 2560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7168)
[M::mem_pestat] mean and std.dev: (1337.84, 1677.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 631, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (826.56, 767.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732768 sequences (100000277 bp) in 2.440 CPU sec, 2.438 real sec...
[M::mem_process_seqs] Processed 729126 reads in 221.079 CPU sec, 7.146 real sec
sorting block 87, #reads = 1073603 mem = 536878438 peak = 1059422208
[M::mem_process_seqs] Processed 734934 reads in 145.439 CPU sec, 4.760 real sec
sorting block 88, #reads = 1072185 mem = 536882473 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290453, 47, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 470, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (570.05, 453.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 172, 240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 470)
[M::mem_pestat] mean and std.dev: (189.11, 84.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 585)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 663, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3489)
[M::mem_pestat] mean and std.dev: (842.27, 779.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 336, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (489.12, 447.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730864 sequences (100000074 bp) in 2.816 CPU sec, 3.002 real sec...
[M::process] read 730294 sequences (100000125 bp) in 1.860 CPU sec, 1.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 289904, 85, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 511, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074)
[M::mem_pestat] mean and std.dev: (928.47, 958.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 477)
[M::mem_pestat] mean and std.dev: (190.71, 85.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 412, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2294)
[M::mem_pestat] mean and std.dev: (459.23, 465.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 682, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (668.27, 522.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 733550 reads in 197.716 CPU sec, 6.434 real sec
[M::mem_process_seqs] Processed 732768 reads in 135.744 CPU sec, 4.476 real sec
sorting block 89, #reads = 1082730 mem = 536880082 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 289937, 53, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 370, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (449.27, 378.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.52, 86.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 351, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3897)
[M::mem_pestat] mean and std.dev: (754.83, 875.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 477, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (814.06, 731.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729398 sequences (100000188 bp) in 3.303 CPU sec, 3.547 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 290052, 85, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 383, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (487.46, 435.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.67, 87.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 415, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (494.43, 447.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 408, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (594.10, 525.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729120 sequences (100000190 bp) in 2.257 CPU sec, 2.255 real sec...
[M::mem_process_seqs] Processed 730864 reads in 198.702 CPU sec, 6.467 real sec
sorting block 90, #reads = 1083623 mem = 536882700 peak = 1059422208
[M::mem_process_seqs] Processed 730294 reads in 137.311 CPU sec, 4.548 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 289141, 38, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 637, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (716.45, 607.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (194.96, 88.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 292, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (379.28, 352.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 337, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2676)
[M::mem_pestat] mean and std.dev: (511.24, 525.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1082525 mem = 536881061 peak = 1059422208
[M::process] read 729506 sequences (100000113 bp) in 3.325 CPU sec, 3.470 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 289428, 44, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 357, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (509.76, 460.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.43, 90.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 620, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3992)
[M::mem_pestat] mean and std.dev: (911.27, 963.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 409, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (596.18, 558.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729344 sequences (100000049 bp) in 2.470 CPU sec, 2.473 real sec...
[M::mem_process_seqs] Processed 729398 reads in 222.426 CPU sec, 7.250 real sec
[M::mem_process_seqs] Processed 729120 reads in 162.894 CPU sec, 5.364 real sec
sorting block 92, #reads = 1080611 mem = 536885207 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 289595, 64, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 494, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (564.28, 467.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.01, 88.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 595, 1924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5298)
[M::mem_pestat] mean and std.dev: (1171.41, 1219.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 391, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3199)
[M::mem_pestat] mean and std.dev: (543.13, 530.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728102 sequences (100000069 bp) in 3.013 CPU sec, 3.145 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 289163, 54, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 361, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2794)
[M::mem_pestat] mean and std.dev: (570.29, 643.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.68, 89.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 616, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (857.28, 826.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 589, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2610)
[M::mem_pestat] mean and std.dev: (703.18, 566.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727756 sequences (100000167 bp) in 2.529 CPU sec, 2.531 real sec...
[M::mem_process_seqs] Processed 729506 reads in 207.454 CPU sec, 6.749 real sec
[M::mem_process_seqs] Processed 729344 reads in 141.580 CPU sec, 4.620 real sec
sorting block 93, #reads = 1079643 mem = 536881769 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 288968, 77, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 563, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (719.40, 548.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.27, 90.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 789, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (874.47, 773.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4909)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 352, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (624.53, 612.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728782 sequences (100000178 bp) in 3.171 CPU sec, 3.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288369, 89, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 425, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (510.59, 448.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.45, 90.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 716, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3890)
[M::mem_pestat] mean and std.dev: (931.94, 786.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 381, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (596.29, 552.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728102 reads in 169.211 CPU sec, 5.487 real sec
sorting block 94, #reads = 1079719 mem = 536880316 peak = 1059422208
[M::mem_process_seqs] Processed 727756 reads in 122.816 CPU sec, 3.869 real sec
[M::process] read 727412 sequences (100000186 bp) in 2.838 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288531, 65, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 554, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (693.04, 583.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.56, 89.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 492, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (658.56, 623.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 463, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (537.55, 452.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3031)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1078815 mem = 536886329 peak = 1059422208
[M::process] read 727688 sequences (100000069 bp) in 3.412 CPU sec, 3.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 287812, 64, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 345, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (652.79, 697.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.94, 90.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 719, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4966)
[M::mem_pestat] mean and std.dev: (962.76, 955.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 404, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (661.10, 610.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728782 reads in 205.789 CPU sec, 6.552 real sec
[M::mem_process_seqs] Processed 727412 reads in 148.675 CPU sec, 4.696 real sec
[M::process] read 727516 sequences (100000207 bp) in 3.487 CPU sec, 3.619 real sec...
sorting block 96, #reads = 1078390 mem = 536879446 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 287862, 89, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 418, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (558.16, 518.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.91, 90.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 465, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074)
[M::mem_pestat] mean and std.dev: (750.79, 943.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 327, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (490.66, 444.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727470 sequences (100000261 bp) in 3.291 CPU sec, 3.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287427, 72, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 318, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (513.67, 506.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.95, 91.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 674, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3302)
[M::mem_pestat] mean and std.dev: (690.11, 676.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 315, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (388.86, 284.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727688 reads in 194.406 CPU sec, 6.191 real sec
[M::process] read 726530 sequences (100000221 bp) in 2.189 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 727516 reads in 134.882 CPU sec, 4.449 real sec
sorting block 97, #reads = 1076435 mem = 536884864 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287598, 65, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 399, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (580.69, 494.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.76, 89.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 535, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (593.84, 548.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 397, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (544.33, 484.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726152 sequences (100000231 bp) in 2.624 CPU sec, 2.755 real sec...
[M::process] read 725986 sequences (100000227 bp) in 1.848 CPU sec, 1.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (134, 287314, 82, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 454, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (586.43, 508.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.44, 90.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 735, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4477)
[M::mem_pestat] mean and std.dev: (961.68, 1097.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 433, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2728)
[M::mem_pestat] mean and std.dev: (649.62, 603.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727470 reads in 197.631 CPU sec, 6.483 real sec
sorting block 98, #reads = 1077754 mem = 536876647 peak = 1059422208
[M::mem_process_seqs] Processed 726530 reads in 143.123 CPU sec, 4.552 real sec
sorting block 99, #reads = 1074969 mem = 536878757 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287426, 61, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 425, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (532.44, 417.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (198.31, 90.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 512, 2185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6063)
[M::mem_pestat] mean and std.dev: (1270.21, 1571.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 409, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (685.21, 627.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725804 sequences (100000258 bp) in 3.557 CPU sec, 3.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286962, 71, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 286, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (515.34, 470.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.85, 91.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 702, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4778)
[M::mem_pestat] mean and std.dev: (901.56, 867.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 552, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (688.26, 605.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726710 sequences (100000228 bp) in 2.550 CPU sec, 2.544 real sec...
[M::mem_process_seqs] Processed 726152 reads in 217.059 CPU sec, 7.063 real sec
[M::mem_process_seqs] Processed 725986 reads in 154.416 CPU sec, 5.081 real sec
sorting block 100, #reads = 1076442 mem = 536880120 peak = 1059422208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286877, 63, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 498, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (652.61, 589.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.91, 91.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 520, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (607.68, 572.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 402, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2826)
[M::mem_pestat] mean and std.dev: (663.15, 628.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 735772 sequences (100000020 bp) in 3.515 CPU sec, 3.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286837, 92, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 461, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (575.91, 501.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.13, 90.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 550, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3930)
[M::mem_pestat] mean and std.dev: (852.49, 887.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 470, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2857)
[M::mem_pestat] mean and std.dev: (781.68, 735.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 737588 sequences (100000197 bp) in 2.530 CPU sec, 2.527 real sec...
[M::mem_process_seqs] Processed 725804 reads in 230.782 CPU sec, 7.483 real sec
sorting block 101, #reads = 1071437 mem = 536880223 peak = 1059422208
[M::mem_process_seqs] Processed 726710 reads in 167.033 CPU sec, 5.290 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 289931, 75, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 502, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (545.76, 428.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 169, 234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 454)
[M::mem_pestat] mean and std.dev: (185.06, 81.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 564)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 490, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (775.96, 727.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 415, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (627.07, 544.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 735934 sequences (100000296 bp) in 3.629 CPU sec, 3.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 291463, 48, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 397, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (625.94, 641.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (123, 168, 232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 450)
[M::mem_pestat] mean and std.dev: (183.16, 79.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 559)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 689, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (790.86, 644.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 379, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (531.14, 486.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734494 sequences (100000222 bp) in 2.417 CPU sec, 2.420 real sec...
[M::mem_process_seqs] Processed 735772 reads in 234.227 CPU sec, 7.414 real sec
sorting block 102, #reads = 1068206 mem = 536879316 peak = 1059422208
[M::mem_process_seqs] Processed 737588 reads in 156.553 CPU sec, 4.956 real sec
sorting block 103, #reads = 1072887 mem = 536878550 peak = 1117683712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 290874, 55, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 473, 1861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5073)
[M::mem_pestat] mean and std.dev: (1125.05, 1214.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 170, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 460)
[M::mem_pestat] mean and std.dev: (185.99, 82.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 572)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 387, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4043)
[M::mem_pestat] mean and std.dev: (661.43, 852.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 373, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (535.70, 422.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733608 sequences (100000186 bp) in 3.124 CPU sec, 3.312 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 290523, 57, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 471, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4494)
[M::mem_pestat] mean and std.dev: (894.94, 1186.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 171, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 467)
[M::mem_pestat] mean and std.dev: (188.19, 84.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 581)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 598, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231)
[M::mem_pestat] mean and std.dev: (826.02, 787.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 574, 2005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5505)
[M::mem_pestat] mean and std.dev: (949.78, 1056.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732454 sequences (100000068 bp) in 2.029 CPU sec, 2.023 real sec...
[M::mem_process_seqs] Processed 735934 reads in 190.442 CPU sec, 6.211 real sec
[M::mem_process_seqs] Processed 734494 reads in 120.695 CPU sec, 3.989 real sec
sorting block 104, #reads = 1078345 mem = 536879969 peak = 1117683712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 290128, 71, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 641, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4060)
[M::mem_pestat] mean and std.dev: (798.07, 820.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5343)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 172, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 473)
[M::mem_pestat] mean and std.dev: (189.73, 85.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 589)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 660, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (605.92, 501.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2961)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 540, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (607.42, 527.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731694 sequences (100000095 bp) in 2.802 CPU sec, 2.918 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 289844, 68, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 420, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (455.64, 342.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 477)
[M::mem_pestat] mean and std.dev: (191.02, 86.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 589, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (675.60, 615.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 542, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (828.73, 789.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730916 sequences (100000147 bp) in 2.150 CPU sec, 2.145 real sec...
[M::mem_process_seqs] Processed 733608 reads in 192.108 CPU sec, 6.248 real sec
sorting block 105, #reads = 1076269 mem = 536880459 peak = 1117683712
[M::mem_process_seqs] Processed 732454 reads in 133.790 CPU sec, 4.252 real sec
sorting block 106, #reads = 1077534 mem = 536881634 peak = 1117683712
[M::process] read 731582 sequences (100000224 bp) in 2.794 CPU sec, 2.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 289677, 67, 127)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 482, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782)
[M::mem_pestat] mean and std.dev: (624.27, 553.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.52, 88.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 576, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (720.97, 632.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 523, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (603.58, 432.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731328 sequences (100000084 bp) in 2.059 CPU sec, 2.057 real sec...
[M::mem_process_seqs] Processed 730916 reads in 104.049 CPU sec, 3.283 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 289694, 54, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 307, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (413.92, 304.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 483)
[M::mem_pestat] mean and std.dev: (192.37, 87.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 602)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 502, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (629.55, 578.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 387, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (580.98, 461.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 289039, 65, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 463, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (505.46, 401.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 480)
[M::mem_pestat] mean and std.dev: (191.90, 87.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 598)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 808, 1954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5492)
[M::mem_pestat] mean and std.dev: (923.30, 853.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 360, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (557.97, 487.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731656 sequences (100000211 bp) in 2.221 CPU sec, 2.223 real sec...
[M::mem_process_seqs] Processed 731694 reads in 290.106 CPU sec, 9.188 real sec
sorting block 107, #reads = 1078363 mem = 536883758 peak = 1117683712
[M::mem_process_seqs] Processed 731582 reads in 152.652 CPU sec, 5.165 real sec
sorting block 108, #reads = 1076740 mem = 536887861 peak = 1117683712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 289440, 70, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 324, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (536.38, 482.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (192.94, 88.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 828, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4350)
[M::mem_pestat] mean and std.dev: (989.88, 879.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 505, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (540.89, 401.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729244 sequences (100000067 bp) in 2.812 CPU sec, 2.967 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 289545, 66, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 344, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (573.88, 632.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 480)
[M::mem_pestat] mean and std.dev: (191.68, 86.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 598)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 811, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3469)
[M::mem_pestat] mean and std.dev: (749.55, 693.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 720, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5038)
[M::mem_pestat] mean and std.dev: (1068.32, 1163.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727640 sequences (100000042 bp) in 1.879 CPU sec, 1.873 real sec...
[M::mem_process_seqs] Processed 731328 reads in 173.848 CPU sec, 5.811 real sec
[M::mem_process_seqs] Processed 731656 reads in 119.349 CPU sec, 3.944 real sec
sorting block 109, #reads = 1078393 mem = 536879666 peak = 1117683712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288098, 68, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 389, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (583.32, 601.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (194.89, 88.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 520, 2070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5948)
[M::mem_pestat] mean and std.dev: (1022.54, 1240.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 418, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (597.70, 585.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727172 sequences (100000242 bp) in 2.959 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287441, 62, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 349, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (426.03, 354.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.48, 90.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 656, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4603)
[M::mem_pestat] mean and std.dev: (972.56, 1058.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 369, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (616.01, 602.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725972 sequences (100000026 bp) in 1.810 CPU sec, 1.818 real sec...
[M::mem_process_seqs] Processed 729244 reads in 184.455 CPU sec, 6.018 real sec
sorting block 110, #reads = 1077040 mem = 536881037 peak = 1117683712
[M::mem_process_seqs] Processed 727640 reads in 123.336 CPU sec, 4.048 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 287223, 71, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 471, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (608.43, 544.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.70, 91.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 594, 1738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4868)
[M::mem_pestat] mean and std.dev: (984.34, 1041.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 480, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3322)
[M::mem_pestat] mean and std.dev: (703.92, 662.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725494 sequences (100000166 bp) in 2.814 CPU sec, 2.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286648, 76, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 417, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (575.36, 545.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.91, 90.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 447, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (504.60, 492.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 497, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3198)
[M::mem_pestat] mean and std.dev: (688.82, 637.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724636 sequences (100000169 bp) in 2.080 CPU sec, 2.081 real sec...
[M::mem_process_seqs] Processed 727172 reads in 174.735 CPU sec, 5.668 real sec
sorting block 111, #reads = 1074455 mem = 536881054 peak = 1117683712
[M::mem_process_seqs] Processed 725972 reads in 117.964 CPU sec, 3.880 real sec
sorting block 112, #reads = 1075805 mem = 536881170 peak = 1150779392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287176, 63, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 348, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (597.62, 588.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.79, 89.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 557, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (729.27, 696.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 381, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (505.90, 396.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724160 sequences (100000144 bp) in 3.168 CPU sec, 3.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286608, 64, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 626, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (664.57, 497.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.51, 91.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 519, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3937)
[M::mem_pestat] mean and std.dev: (798.97, 749.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 441, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3578)
[M::mem_pestat] mean and std.dev: (762.46, 680.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725494 reads in 163.789 CPU sec, 5.334 real sec
[M::process] read 724874 sequences (100000196 bp) in 2.102 CPU sec, 2.133 real sec...
[M::mem_process_seqs] Processed 724636 reads in 113.974 CPU sec, 3.745 real sec
sorting block 113, #reads = 1075068 mem = 536879178 peak = 1150779392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (122, 286446, 59, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 402, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (650.43, 588.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.62, 91.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 278, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3094)
[M::mem_pestat] mean and std.dev: (654.25, 731.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 531, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (707.43, 700.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724206 sequences (100000283 bp) in 2.629 CPU sec, 2.747 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286829, 72, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 640, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3545)
[M::mem_pestat] mean and std.dev: (800.28, 695.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.94, 92.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 383, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (536.61, 564.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 578, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3431)
[M::mem_pestat] mean and std.dev: (732.93, 657.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724376 sequences (100000224 bp) in 1.870 CPU sec, 1.870 real sec...
[M::mem_process_seqs] Processed 724160 reads in 166.934 CPU sec, 5.454 real sec
sorting block 114, #reads = 1074108 mem = 536882899 peak = 1150779392
[M::mem_process_seqs] Processed 724874 reads in 112.157 CPU sec, 3.596 real sec
[M::process] read 286108 sequences (39422069 bp) in 1.436 CPU sec, 1.515 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286246, 74, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 407, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (548.48, 479.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.64, 92.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 591, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (772.67, 887.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 434, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (708.47, 700.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 115, #reads = 1075083 mem = 536883350 peak = 1150779392
[M::mem_process_seqs] Processed 724206 reads in 90.234 CPU sec, 2.992 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 286495, 79, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 452, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (617.78, 536.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.61, 92.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 387, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233)
[M::mem_pestat] mean and std.dev: (575.62, 635.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 359, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (628.85, 655.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 113065, 35, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 392, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (702.39, 693.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.29, 92.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 635, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (797.91, 749.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (370, 599, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (720.00, 507.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724376 reads in 138.933 CPU sec, 4.529 real sec
[M::mem_process_seqs] Processed 286108 reads in 57.503 CPU sec, 1.857 real sec
sorting block 116, #reads = 1077232 mem = 536883948 peak = 1150779392
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 125416616
overall: 70256340992 mem 21509.568 user 407.456 sys 723.766 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 723.805 sec; CPU: 21917.027 sec
sorting block 117, #reads = 716746 mem = 358437260 peak = 1153540096
uniq header count 1
merging 118 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7004458428
output reads: 126823024
bam_mem_sort: 118 calls 66.783 user 2.261 sys 69.254 real
bam_write: 118 calls 38.162 user 2.528 sys 41.099 real
execute: 1 calls 35.610 user 2.602 sys 770.571 real
merge_files: 1 calls 35.574 user 2.575 sys 46.194 real
parse_chunk: 1883 calls 103.893 user 24.374 sys 130.285 real
read_chunk: 5114 calls 56.533 user 39.898 sys 679.084 real
sort_block: 1 calls 39.966 user 39.271 sys 656.907 real
write_chunk: 3229 calls 35.162 user 2.204 sys 45.088 real
overall: 3829952512 mem 1851.741 user 96.799 sys 770.594 real
ls: cannot access '*.cram': No such file or directory